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Reaction to Avandia Warnings Stronger Among Internists Than,Endocrinologists, According to Study by GfK Market Measures

Measures research also identified Januvia and Januvamet as the therapies most likely to benefit from the Avandia switches implemented by all groups of physicians treating type 2 patients.

"While the news of Avandia's cardiovascular risk may provide a barrier for some physicians to any oral medications, on the other hand it could also expedite patients to insulin," said Napolitano. "About 30 percent of both internists and endocrinologists report a high likelihood to switch patients to insulin sooner due to the Avandia news."

200 Physicians Reveal Anticipated Actions

Reflecting views from 200 physicians who see no fewer than 10 type 2 diabetes patients per week, GfK Market Measures' Event Flash, Physicians' Reactions to NEJM's Results on Avandia's Increased CV Risk, provides an immediate read of physicians' reaction to the NEJM report. Using an Internet methodology, general/family practitioners, internists and endocrinologists expressed their expectations by responding to a survey that was self administered.

Both Avandia and ACTOS have been asked to add "black box" warnings on their labels while the FDA continues to investigate. On July 30, 2007, the FDA's Endocrinologic and Metabolic Drugs Advisory Committee and Drug Safety and Risk Management Advisory Committee will meet to discuss the cardiovascular ischemic and thrombotic (heart-related) risks of thiazolidinediones, focusing particularly on rosiglitazone (Avandia).

About GfK Market Measures

GfK Market Measures provides healthcare clients with a unique mix of custom and syndicated solutions to support the full marketing continuum, including market assessment, brand tracking, sales force effectiveness, healthcare consumer and product launch applications. GfK Market Measures is a member of the GfK U.S. Healthcare Companies, the largest provider of custom healthcare marketing research services in the United States. For further information please visit www.gfkmarketmeasures.co
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