Navigation Links
Progenics Announces Positive Results in Clinical Trial of Novel HIV,Therapy

TARRYTOWN, N.Y.--(BUSINESS WIRE)--May 1, 2007 - Progenics Pharmaceuticals, Inc. (NASDAQ: PGNX) today announced positive results from the first clinical trial of its investigational drug, PRO 140, in individuals infected with the human immunodeficiency virus (HIV), the causative agent of AIDS. Patients receiving a single 5.0 mg/kg dose of PRO 140 achieved an average maximum decrease of viral concentrations in the blood of 98.5% (1.83 log10), with individual reductions ranging up to 99.7% (2.5 log10). In these patients, reductions in viral load of greater than 90% (1.0 log10) on average persisted for two to three weeks after dosing. In addition, PRO 140 was generally well tolerated in this phase 1b proof-of-concept study. PRO 140 was granted Fast Track status from the U.S. Food and Drug Administration (FDA), and Progenics plans to initiate additional clinical testing in the second half of 2007.

"This study establishes clear proof of concept for PRO 140 as a potent antiretroviral agent with extended activity following a single dose," said Scott M. Hammer, M.D., Chief, Division of Infectious Diseases and Harold C. Neu Professor of Medicine, Columbia University College of Physicians and Surgeons, New York City. "The primary goal of HIV therapy is to provide maximal and durable suppression of viral replication. Based on this study, PRO 140 has the potential to add to the armamentarium of drugs that can help achieve this goal in patients living with HIV, including those whose treatment options are limited by drug resistance."

PRO 140 is a humanized monoclonal antibody that binds CCR5, the principal portal used by HIV to enter cells. Viral-entry inhibition using a long-lived antibody represents a promising novel approach to treating HIV infection. Unlike currently available antiretroviral drugs, PRO 140 does not target the virus, but rather binds to the CCR5 receptor on healthy immune system cells and thereby pr
'"/>




Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Progenics and Wyeth Announce Positive Results from Three-Month Clinical-Extension Study of Subcutaneous Methylnaltrexone for the Treatment of Opioid-Induced Constipation in Patients with Advanced Illness
2. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
3. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
5. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
6. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
7. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
8. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
9. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
10. Protox Announces Positive Clinical Data from Prostate Cancer Study
11. Inspire Announces Webcast of Presentation at C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
Post Your Comments:
(Date:9/16/2014)... 16, 2014   Evana Automation Specialists , a ... and test systems, recently received a contract to provide ... manufacturer. The Evana solution will help error-proof the process ... well as reduce labor. A catheter ... robotic assembly cell. The robot will pick the adapter, ...
(Date:9/16/2014)... Conn. , Sept. 16, 2014   ... owned subsidiary of TriStar Wellness Solutions(R), Inc. ... marketer of advanced medical products, announced today that ... has grown by 39 percent, and microdispersed oxidized ... though August 2014.  Overall, TWSI expects third quarter ...
(Date:9/16/2014)... On September 25 to 26, 2014, China,s ... manufacturing - MEDTEC China  - will mark its 10th ... Center, bringing together close to 300 leading global suppliers ... medical-grade raw materials, parts and processing technologies. ... visitor pre-registration to be completed. To date, more than ...
Breaking Medicine Technology:Evana Automation to Supply Robotic Assembly Cell to Leading Medical Device Manufacturer 2Evana Automation to Supply Robotic Assembly Cell to Leading Medical Device Manufacturer 3HemCon Medical Technologies, Inc. Projects Strong Third Quarter Revenues 2HemCon Medical Technologies, Inc. Projects Strong Third Quarter Revenues 3HemCon Medical Technologies, Inc. Projects Strong Third Quarter Revenues 4MEDTEC China 2014: Seven Highlights Not to Miss! 2MEDTEC China 2014: Seven Highlights Not to Miss! 3MEDTEC China 2014: Seven Highlights Not to Miss! 4
...  Bionovo, Inc. (Nasdaq: BNVI, BNVID) announced today that it ... effective with the opening of trading on August 31, 2010. ... this time is to better enable the company to maintain ... Market. The company,s common stock will continue trading on The ...
... Laerdal Medical has been at the cutting ... launched its famous Resusci Anne in 1960. Fifty ... as it launches its latest SimMan patient simulator, ... ) (Photo: http://www.newscom.com/cgi-bin/prnh/20100830/NY56743 ) ...
Cached Medicine Technology:Bionovo Announces Reverse Stock Split 2Bionovo Announces Reverse Stock Split 3Laerdal Introduces SimMan Essential 2Laerdal Introduces SimMan Essential 3
(Date:9/16/2014)... Terminsurancevirginia.com has released a new blog post ... insurance for obese clients. , Obese clients can ... It is unlikely for applicants to be denied coverage ... insurance costs. , Having life insurance is important ... insurance is available as temporary or permanent coverage and ...
(Date:9/16/2014)... Insuranceservicecompany.com has released a new blog ... investment tool. , Whole life insurance can provide financial ... used as an investment tool. Clients can save money for ... , A whole life insurance plan features a savings ... order for this policy to be profitable, clients should purchase ...
(Date:9/16/2014)... adage that warns against passing judgment based on ... species, apparently don,t share such human wisdom when ... University Polytechnic School of Engineering found that female ... fin color: yellow. The preference for yellow was ... , The reason may lie in the engineering-based, ...
(Date:9/16/2014)... According to a report by iData Research ( ... market research, the market for enteral feeding devices is ... U.S . and Europe combined. The market ... tubes, DPEJ tubes, PEG/J tubes. The enteral feeding replacement ... non-balloon tubes, nasogastric and nasojejunal tubes, enteral feeding pumps ...
(Date:9/16/2014)... 2014 Care Logistics® announced the ... of the Hospital Operating System™ that allows hospitals ... with staff capacity. For the first time, bed ... nursing and other staff capacity. , “The Demand ... anticipated admissions, discharges and transfers, real staff capacity ...
Breaking Medicine News(10 mins):Health News:Obese Clients Can Find Affordable No Exam Term Life Insurance at Terminsurancevirginia.com! 2Health News:Whole Life Insurance Can Be A Good Investment Tool for Retirement! 2Health News:Judging a fish by its color: for female bluefin killifish, love is a yellow mate 2Health News:Judging a fish by its color: for female bluefin killifish, love is a yellow mate 3Health News:Over 17 Million Enteral Feeding Device Placement Procedures is Expected to be Performed in the U.S. and Europe in 2020: Market Led by Covidien, Kimberly-Clark and Abbott 2Health News:Over 17 Million Enteral Feeding Device Placement Procedures is Expected to be Performed in the U.S. and Europe in 2020: Market Led by Covidien, Kimberly-Clark and Abbott 3Health News:Care Logistics Launches Demand Logistics as Part of the Hospital Operating System 2
... ) launches the GlaceComplete product suite which seamlessly integrates EMR ... billing process. The product has been designed to reduce the ... for the average office based medical practice. , ... ...
... piezoelectric transducers in industrial applications, and to facilitate transducer evaluation in ... ... 26, 2009 -- Piezoelectric elements have a myriad of uses. They ... in a structure. They can be used to acoustically cancel noise, ...
... that is responsible for maintaining the health of the light-sensing ... retina for the first time. , The ability to see ... of many diseases of the eye long before a patient ... Investigative Ophthalmology and Visual Science ., "Our goal is to ...
... Feb. 25 PharmaNet Development Group, Inc. (the "Company") ... clinical development services, today reported preliminary net income for ... million, or $0.08 per diluted share, compared to net ... per diluted share, in the fourth quarter 2007. All ...
... for February 26, 2009 at 10:00 a.m. EST , EAST ... SVNT ) today reported financial results for the three months and ... 2008, the Company had a net loss of $24.2 million, or ... the year ended December 31, 2008, the Company had a net ...
... with record bookings and continued positive cash flow ... AMCS ), a leader in radiology ... reported unaudited financial results for the fourth quarter ... http://www.newscom.com/cgi-bin/prnh/20060202/AMICASLOGO ) Q4 Financial Highlights Revenue ...
Cached Medicine News:Health News:Glenwood Systems, LLC Improves Medical Billing Process with GlaceComplete 2Health News:Glenwood Systems, LLC Improves Medical Billing Process with GlaceComplete 3Health News:Amped Up Piezos Are On The Move - Driving Piezos with an Affordable High Voltage Piezo Amplifier QPA200 2Health News:Amped Up Piezos Are On The Move - Driving Piezos with an Affordable High Voltage Piezo Amplifier QPA200 3Health News:'Dark cells' of living retina imaged for the first time 2Health News:'Dark cells' of living retina imaged for the first time 3Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 2Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 3Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 4Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 5Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 6Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 7Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 8Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 9Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 10Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 11Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 12Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 13Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 14Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 15Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 16Health News:PharmaNet Development Group Reports Fourth Quarter and Full Year 2008 Preliminary Financial Results 17Health News:Savient Pharmaceuticals Reports Fourth Quarter and Year-End 2008 Financial Results 2Health News:Savient Pharmaceuticals Reports Fourth Quarter and Year-End 2008 Financial Results 3Health News:Savient Pharmaceuticals Reports Fourth Quarter and Year-End 2008 Financial Results 4Health News:Savient Pharmaceuticals Reports Fourth Quarter and Year-End 2008 Financial Results 5Health News:Savient Pharmaceuticals Reports Fourth Quarter and Year-End 2008 Financial Results 6Health News:Savient Pharmaceuticals Reports Fourth Quarter and Year-End 2008 Financial Results 7Health News:Savient Pharmaceuticals Reports Fourth Quarter and Year-End 2008 Financial Results 8Health News:Savient Pharmaceuticals Reports Fourth Quarter and Year-End 2008 Financial Results 9Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 2Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 3Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 4Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 5Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 6
Ruschelit® PVC. Siliconized. Stainless steel spiral reinforced. High volume/low pressure cuff. Permanent connector. X-ray opaque. Single use. Sterile...
Tube for Right Bronchus - Ruschelit™ PVC. Color coded for easy identification of ports, balloons and 15mm connectors. High volume/low pressure cuffs. With Carina hook. X-ray opaque line. Gradua...
... For Laryngotracheal Instillation of Topical Anesthetic, ... populations, this cuffed tube incorporates an ... spray application of topical anesthetic above ... offers three endotracheal tubes designs which ...
SPIRAL-FLEX® Reinforced Oral/Nasal Uncuffed Endotracheal Tubes...
Medicine Products: