NEWTON, Mass.--(BUSINESS WIRE)--May 17, 2007 - Pro-Pharmaceuticals,
Inc. (Amex: PRW), a developer of novel, first-in-class carbohydrate
compounds today announced that Eliezer Zomer, Ph.D., Executive Vice
President, Product Development and Manufacturing will present,
"Pharmacokinetic Translational Study in Advanced Solid Tumors of
5-FU with an Admixture of a Galactomannan Derivative," at the
International Society of Oncodevelopmental Biology and Medicine
(ISOBM) Conference to be held in Prague, Czech Republic, September
15-19, 2007.
"The pharmacokinetic profile of 5-FU co-administered with
DAVANAT(R) in mouse models has translated well in patients with
solid tumors," said Dr. Eliezer Zomer. "The patient data revealed
varied increases of 5-FU exposure in individual patients with no
corresponding effects on safety measurements. These findings
warrant further investigation to determine whether the increased
efficacy of 5-FU with DAVANAT(R) in animal models translate into
clinical benefit for patients. We are encouraged with the clinical
data of DAVANAT(R) /5-FU as observed in our Phase I and Phase II
trials and look forward to confirming the benefit of this
combination therapy in our ongoing Phase II trials for colorectal
and biliary cancer."
ISOBM Conference
The International Society of Oncodevelopmental Biology and
Medicine (ISOBM) is a leading society for scientists, clinicians
and company members developing and validating assays for tumor
diagnostics and management of cancer therapy. The scientific
program will present new discoveries in the research of tumor cell
biology (carcinogenesis, oncogenes and tumor suppressor genes,
metastasis formation/invasion, angiogenesis) as well as clinical
applications of tumor markers - established and new ones - for
tumor diagnostics and therapy guiding for various cancers (breast,
ovary, prostate, colon, melanoma, others).
Phase II, First Line, Colorecta
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