Navigation Links
Prana Biotechnology Presents New Key Findings on PBT2

PBT2 Alters Biomarkers and Rapidly Improves Cognition in two distinct models of Alzheimer's Disease

MELBOURNE, Australia - June 7, 2007 - Prana Biotechnology Limited (NASDAQ: PRAN / ASX: PBT), a biopharmaceutical company focused on the research and development of treatments for neurodegenerative disorders, announced today that it will present new data on Prana's lead Alzheimer's disease (AD) drug PBT2 at the Alzheimer's Association International Conference on Prevention of Dementia, in Washington D.C.

Professor Colin Masters MD, Executive Director and Laureate Professor Mental Health Research Institute and The National Neuroscience Facility University of Melbourne and Director of the Company will present the findings on June 9, in a lecture entitled "Alzheimer's Disease: Abeta amyloid as the principal molecular therapeutic and diagnostic target." The presentation will include data from manuscripts currently under preparation for publication by scientists from Prana, The Mental Health Research Institute and The University of Melbourne.

While PBT2 is currently in Phase IIa development, the presentation will detail the results of the expansive mouse cognitive and biomarker studies recently completed on PBT2, including several key findings such as:

* PBT2 potently inhibits synthetic Abeta forming toxic soluble oligomers in vitro; * PBT2 reduces Abeta oligomer levels detected in secretions from the brains of conscious, freely-moving AD transgenic mice within 4hrs of oral administration. This observation was reproduced in two genetically distinct mouse models. * PBT2 sharply improves cognitive performance in the Morris Water Maze for two genetically distinct mouse models of AD within 5 to 7 days of treatment; and * The brains of the mice with improved cognition showed a substantial reduction in the biomarkers phosphorylated tau and Abeta, while simultaneously raising the level of the neuronal mar
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Generex Biotechnology to Make Presentations At 46th Annual Meeting of the European Society of Pediatric Endocrinology
2. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ESMO Conference
3. Cytos Biotechnology Reports Results from Phase IIa Study with CYT003-QbG10 in Patients Suffering from Atopic Dermatitis
4. Beike Biotechnology Study Suggests Adult Stem Cells Show Promise for Peripheral Vascular Disease
5. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ASCO Annual Meeting
6. Generex Biotechnology Vaccine Strategy Presented at International Conference in London
7. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at AUA Annual Meeting
8. Cougar Biotechnology Presents Positive CB7630 Clinical Data at AACR Annual Meeting Late-Breaking Clinical Trials Session
9. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
10. European Society for Medical Oncology (ESMO) Presents Data from the Clinical Trial of MediGenes Cancer-Killing Virus in Press Conference
11. Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity and Safety Profile of Quadramet at International Myeloma Workshop
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Prana Biotechnology Presents New Key Findings PBT2
(Date:5/28/2015)... HOUSTON , May 28, 2015 /PRNewswire/ - ... reported financial results for the second quarter and three and ... are expressed in Canadian dollars and in accordance with International ... ESSA recorded a net loss of $5.9 million ... 31, 2015 (Q2-2015), compared to a net loss of $0.4 ...
(Date:5/28/2015)... 2015 Research and ... of Jain PharmaBiotech,s new report  "RNAi - ... offering.       (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ... involves the use of double stranded RNA ... is processed into short 21-23 nucleotide RNAs ...
(Date:5/28/2015)... MELVILLE, N.Y. , May 28, 2015 /PRNewswire/ ... ), the world,s largest provider of health care ... and medical practitioners, today reminded its customers that ... for dentists, physicians and veterinarians who experience operational, ... the disastrous storms in the South Central region ...
Breaking Medicine Technology:Essa Pharma Inc. Reports Second Quarter 2015 Financial Results 2Essa Pharma Inc. Reports Second Quarter 2015 Financial Results 3Essa Pharma Inc. Reports Second Quarter 2015 Financial Results 4Essa Pharma Inc. Reports Second Quarter 2015 Financial Results 5Global RNAi Market Report 2015-2024 - Technologies, Markets and Companies 2Global RNAi Market Report 2015-2024 - Technologies, Markets and Companies 3Henry Schein Disaster Relief Hotline Is Open To Support Customers Affected By Storms In South Central, U.S. 2Henry Schein Disaster Relief Hotline Is Open To Support Customers Affected By Storms In South Central, U.S. 3
... Aug. 8, 2011 Symphony Corporation, a global ... of JGI, a New Jersey-based Human Capital Management ... in the healthcare industry nationally.  Symphony,s acquisition of ... to provide the highest level of benefits to ...
... 2011 Auxilium Pharmaceuticals, Inc. (NASDAQ: AUXL ... James P. Tursi has been promoted to Chief Medical ... Executive Officer and President of Auxilium, and sit on ... (Logo: http://photos.prnewswire.com/prnh/20101202/MM10881LOGO) Dr. Tursi has been ...
Cached Medicine Technology:Symphony Corporation Acquires JGI to Provide End-to-End Services for Healthcare IT 2Auxilium Pharmaceuticals, Inc. Announces Promotion of Dr. James P. Tursi to Chief Medical Officer 2Auxilium Pharmaceuticals, Inc. Announces Promotion of Dr. James P. Tursi to Chief Medical Officer 3
(Date:5/28/2015)... (PRWEB) May 29, 2015 Recently, KORT Richmond, ... helping amputees regain their quality of life. The program works ... have had one for years, but are still having difficulty. ... nearly 2 million people living with limb loss in the ... (54%) – including diabetes and peripheral arterial disease – trauma ...
(Date:5/28/2015)... 2015 Today the National Resident Matching ... the 2015 Main Residency Match®. A record-number 30,212 ... filled when the matching algorithm was processed. Of ... the Match Week Supplemental Offer and Acceptance Program® (SOAP®) ... pleased with the outcome of the 2015 Main Residency ...
(Date:5/28/2015)... May 28, 2015 AMVETS National Executive ... the Commission on Care established by Congress to examine ... veterans. , Appointed to the commission by Mitch McConnell, ... be one of only 15 voting members on the ... and Accountability Act of 2014. The goal of the ...
(Date:5/28/2015)... VA (PRWEB) May 28, 2015 ... the 351(k) Application Process, **FDAnews Webinar**, June 23, ... [http://www.fdanews.com/BiosimilarsApproval , On June 23, 2015, ... of two leading intellectual property attorneys from the ... Success Strategies for Biosimilars Approval: A Roadmap to ...
(Date:5/28/2015)... 2015 Restricting access to firearms for ... policies that more clearly define alcohol misuse should be ... existing research and public policies by the UC Davis ... April 30 in the peer-reviewed journal Preventive Medicine ... of alcohol misuse in association with firearm access and ...
Breaking Medicine News(10 mins):Health News:KORT Richmond Physical Therapy Adds New Program to Help Amputees 2Health News:NRMP Releases Results and Data: 2015 Residency Match: Record Number of Positions Filled 2Health News:NRMP Releases Results and Data: 2015 Residency Match: Record Number of Positions Filled 3Health News:AMVETS Executive Director Stewart Hickey Appointed to Congressional Commission on Care 2Health News:FDAnews Announces — Success Strategies for Biosimilars Approval: A Roadmap to the 351(k) Application Process Webinar, June 23, 2015 2Health News:FDAnews Announces — Success Strategies for Biosimilars Approval: A Roadmap to the 351(k) Application Process Webinar, June 23, 2015 3Health News:UC Davis Research Finds That Restricting Firearms Access for People who Misuse Alcohol May Prevent Violence 2Health News:UC Davis Research Finds That Restricting Firearms Access for People who Misuse Alcohol May Prevent Violence 3Health News:UC Davis Research Finds That Restricting Firearms Access for People who Misuse Alcohol May Prevent Violence 4
... difficult economic times, when people,s stress levels - both ... essential than ever, according to the experts at the ... many are today, we need all the help we ... and ADA Spokesperson Amy Jamieson-Petonic. "While eating healthfully is ...
... an affiliate member of ACA International – the Association of Credit ... , ... (Vocus) March 10, 2009 -- Prosodie Interactive, ... 33324-3223, was accepted as an affiliate member of ACA International – ...
... solutions for managing scientific R&D knowledge, information and processes, proudly ... Board of Directors. , ... Cork, ... LTD ("KineMatik"), providers of software solutions for managing scientific ...
... Amilpar ( BOVESPA: AMIL3, Bloomberg: AMIL3 BZ e Reuters: ... today its consolidated results for the periods ended on December ... at 3.2 million at the end of December, 18.4% up ... the previous quarter. , Adjusted Operating Revenues totaled ...
... 11 , New research released to ... (36%) of the nine million smokers in Great Britain are thinking,about ... of the economic,downturn. The poll also shows that one in ten ... on No Smoking Day. , No Smoking ...
... after treatment stops -SAN FRANCISCO, March 10 ... formulation of liquor carbonis distillate (LCD), known as ... cream in improving and controlling the symptoms of ... the American Academy of Dermatology,s 2009 Annual Meeting. ...
Cached Medicine News:Health News:A Registered Dietitian Can Help You Weather Economic Troubles Through Nutrition and Health, Says American Dietetic Association 2Health News:Business Becomes Affiliate Member of International Trade Association 2Health News:Mr. Ruben Jose King-Shaw Jr. to Join KineMatik Board of Directors 2Health News:Mr. Ruben Jose King-Shaw Jr. to Join KineMatik Board of Directors 3Health News:Amilpar - Revenues Increase by 26.5% and Adjusted Net Income Climbs 28.7% in 2008 2Health News:Recession leads 1 in 3 Smokers to cut Down or Quit 2Health News:Recession leads 1 in 3 Smokers to cut Down or Quit 3Health News:Study Shows Nonprescription LCD Topical Solution is More Effective than Prescription-Strength Calcipotriol Cream for Moderate Plaque Psoriasis 2Health News:Study Shows Nonprescription LCD Topical Solution is More Effective than Prescription-Strength Calcipotriol Cream for Moderate Plaque Psoriasis 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: