Navigation Links
Positive Results Using Affitech-Identified Human Antibody That,Blocks VEGF Binding to VEGF Receptor 2 in Preclinical Cancer Model,Reported by Peregrine

OSLO, Norway--(BUSINESS WIRE)--Apr 23, 2007 - Affitech AS, the human antibody therapeutics company announced today that Peregrine Pharmaceuticals, Inc. reported positive in vivo test results of R3, a fully human monoclonal antibody developed by Affitech, in a pancreatic cancer model at the recently concluded Centennial Annual Meeting of the American Association for Cancer Research (AACR). R3 has been designed by the two companies for selective blocking of VEGF (vascular endothelial growth factor) binding to VEGF receptor 2, as opposed to other anti-angiogenic agents which block activity of both VEGF receptors.

The R3 antibody, which was generated by Affitech's phagemid antibody library screening method, when tested by Peregrine on a pancreatic cancer model, showed significant reduction of the growth, vascularization and macrophage infiltration of pancreatic tumors in mice. This is the first antibody from Affitech's library that has been tested in a preclinical development model. Peregrine announced that the positive results of R3 antibody support the Company's intent to progress its anti-VEGF program towards clinical trials.

"We are delighted with this in vivo result, " commented Martin Welschof, Ph.D., Chief Executive Officer of Affitech. "Affitech and Peregrine have several collaborative antibody projects. The quality of the antibody and excellent collaborative research by the scientists of our two organizations are contributing to advancing Peregrine's anti-VEGF portfolio. This success also has important implications for accelerating our own human therapeutic antibody program "

Editors notes

Affitech AS is a privately held human therapeutic antibody discovery and development company with headquarters and R&D facilities in Oslo, Norway and its US subsidiary in the San Francisco Bay Area. The Company's current disease focus is oncology and it utilizes two discrete but unique approaches
'"/>




Page: 1 2

Related medicine technology :

1. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
2. Positive Aggrastat Results Featured in the Journal of the American College of Cardiology
3. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Protox Announces Positive Clinical Data from Prostate Cancer Study
5. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
6. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ESMO Conference
7. TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment
8. Positive ZIO-201 Interim Phase II Sarcoma Data Presented at European Society for Medical Oncology
9. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
10. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
11. Chi-Med Announces Positive Phase II Proof-of-Concept Data for HMPL-004 in Ulcerative Colitis
Post Your Comments:
(Date:7/24/2014)... PARK, Kan. , July 24, 2014 /PRNewswire/ ... of two compounds that will be added to ... with Australian-based CIMTECH Pty Ltd, a biotechnology company. ... PAR 122 have shown promise in bone regeneration ... license to develop the compounds for the veterinary ...
(Date:7/24/2014)... MARSEILLE , Frankreich, July ... , Weltweite Exklusivlizenz der Universität ... Entwicklung von Tests auf SF3B1-Mutationen, einschließlich von ... Neuer Test weist Mutationen des SF3B1-Gens nach, ... einen günstigen Krankheitsverlauf vermuten lassen  ...
(Date:7/24/2014)... Calif., July 24, 2014  Abaxis, Inc. (NasdaqGS: ... blood analysis systems, today reported financial results for the ... First quarter overview: , Revenues of $47.5 million, ... Diluted EPS of $0.21, up 50% over last year,s ... market revenues of $7.2 million, up 20% over last ...
Breaking Medicine Technology:Parnell Acquires License for Intellectual Property and Rights to Develop Compounds for Bone and Dermal Regeneration 2Parnell Acquires License for Intellectual Property and Rights to Develop Compounds for Bone and Dermal Regeneration 3Parnell Acquires License for Intellectual Property and Rights to Develop Compounds for Bone and Dermal Regeneration 4QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 2QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 3QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 4QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 5Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 2Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 3Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 4Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 5Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 6Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 7Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 8Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 9Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 10Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 11
... (Nasdaq: ERES ), a global provider of ... device industries, today announced that Michael McKelvey will be ... Officer and a director of ERT.  The Company,s Board ...  Dr. McKelvey will continue in his current position until ...
... Sept. 10 Covance Inc. (NYSE: CVD ) ... Global Healthcare Conference on Tuesday, September 14, 2010 at 2:10 ... presentation at www.covance.com .  In order to register and ... Covance, with headquarters in Princeton, New Jersey, is ...
Cached Medicine Technology:ERT Announces Upcoming Retirement of Michael McKelvey as Chief Executive Officer 2ERT Announces Upcoming Retirement of Michael McKelvey as Chief Executive Officer 3
(Date:7/25/2014)... 25, 2014 The American Brain Tumor ... Talent Development Trainer of Distinguished Events, and Corporate and ... American Cancer Society, will be joining the ABTA in ... Ward will oversee the roll out of a nationwide ... , The recently launched volunteer network will provide the ...
(Date:7/25/2014)... Chicago, IL (PRWEB) July 25, 2014 “You ... of more than 500 people and their loved ones across ... Association (ABTA), a brain tumor diagnosis is typically met with ... learn a new and difficult vocabulary, and make critical decisions ... a brain tumor diagnosis is accompanied by a sense of ...
(Date:7/25/2014)... IL (PRWEB) July 25, 2014 Today, nearly ... tumor, and yet, when it comes to pinpointing causes or ... now, we don’t know who, we don’t know when, and ... M. Wilson, MNA, president & CEO, American Brain Tumor Association. ... the American Brain Tumor Association funds research to pursue answers ...
(Date:7/25/2014)... July 25, 2014 The North America Artificial ... in North America with analysis and forecast of revenue. The ... from around $4.7 billion in 2013 to around $7 billion ... 2018. , Browse through the TOC of North America ... analysis provided. This also provides a glimpse of the segmentation ...
(Date:7/25/2014)... 25, 2014 The report, "Wireless ... Wi-Fi, Wireless Gigabit Alliance, Access Points, Routers, Residential ... Technology Roadmap and Analysis (2014 - 2019)," provides ... overall market, segmented by WiGig enabled products, and ... segments of the WiGig market, and provides the ...
Breaking Medicine News(10 mins):Health News:American Brain Tumor Association Recruits Director to Lead New Volunteer Network 2Health News:American Brain Tumor Association to Expand Service Reach with Launch of Nationwide Volunteer Network 2Health News:American Brain Tumor Association to Expand Service Reach with Launch of Nationwide Volunteer Network 3Health News:Brain Tumor Causes and Risk Factors Elude Scientists 2Health News:Brain Tumor Causes and Risk Factors Elude Scientists 3Health News:Brain Tumor Causes and Risk Factors Elude Scientists 4Health News:North America Artificial Lift Services Market is Expected to Reach $7 Billion in 2018 - New Report by MicroMarket Monitor 2Health News:North America Artificial Lift Services Market is Expected to Reach $7 Billion in 2018 - New Report by MicroMarket Monitor 3Health News:North America Artificial Lift Services Market is Expected to Reach $7 Billion in 2018 - New Report by MicroMarket Monitor 4Health News:Wireless Gigabit (WiGig) Market Projected to $10.53 Billion by 2019 - New Report by MarketsandMarkets 2Health News:Wireless Gigabit (WiGig) Market Projected to $10.53 Billion by 2019 - New Report by MarketsandMarkets 3Health News:Wireless Gigabit (WiGig) Market Projected to $10.53 Billion by 2019 - New Report by MarketsandMarkets 4
... Jan. 10 Beginning Sunday, Jan. 10 and continuing through ... Disease Control (CDC) to promote National Influenza Vaccination Week. , ... nationwide effort to remind individuals it,s not too late to ... a serious disease. The Centers for Disease Control and Prevention ...
... ... (with over 65 clients in 24 states) announced today that several radiology practices in the ... Santa Fe Imaging in Santa Fe, NM, have signed contracts for billing and practice management ... Columbus, ...
... ... running plastic surgery practice in the nation is launching an expansive new ... Plastic Surgical Group, PC, a practice offering reconstructive and cosmetic surgery ... to provide web visitors with a thorough virtual tour of its facilities ...
... WASHINGTON, Jan. 8 Speaker Nancy Pelosi released the following statement on ... b y the Center for American Progress that ... over the next decade than would be created without reform. The report finds ... States by about 250,000 to 400,000 per year over the coming decade. ...
... ... , Health and Development Groups Applaud Clinton ... coalition of organizations representing millions of Americans applauded today,s statement by Secretary ... consensus that achieving universal access to reproductive health is critical for individual ...
... , , SILVER SPRING, Md., Jan. ... to stop producing and distributing its medical products used in ... compliance with FDA quality standards. The products are considered to ... review and approval for safety and effectiveness. The agreement was ...
Cached Medicine News:Health News:Highmark Supports National Influenza Vaccination Week 2Health News:Highmark Supports National Influenza Vaccination Week 3Health News:ADVOCATE Announces New Partnerships With Centers in the Western U.S. 2Health News:ADVOCATE Announces New Partnerships With Centers in the Western U.S. 3Health News:Long Island Plastic Surgical Practice - the Largest in the U.S. - Opens Virtual Doors on a New, State-of-the-Art Website 2Health News:Long Island Plastic Surgical Practice - the Largest in the U.S. - Opens Virtual Doors on a New, State-of-the-Art Website 3Health News:Long Island Plastic Surgical Practice - the Largest in the U.S. - Opens Virtual Doors on a New, State-of-the-Art Website 4Health News:U.S. Government Rejoins Worldwide Consensus on Reproductive Health 2Health News:U.S. Government Rejoins Worldwide Consensus on Reproductive Health 3Health News:U.S. Government Rejoins Worldwide Consensus on Reproductive Health 4Health News:U.S. Government Rejoins Worldwide Consensus on Reproductive Health 5Health News:U.S. Government Rejoins Worldwide Consensus on Reproductive Health 6Health News:U.S. Government Rejoins Worldwide Consensus on Reproductive Health 7Health News:FDA Requires Sybaritic, Inc. to Stop Producing Unapproved Medical Devices 2Health News:FDA Requires Sybaritic, Inc. to Stop Producing Unapproved Medical Devices 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: