Navigation Links
Positive Results Prompt US National Cancer Institute to Make,Gleevec Available To Patients in Post-Surgical Gist Study

- Gleevec found to dramatically reduce the risk of cancer returning after surgery for Kit-positive gastrointestinal stromal tumors (GIST)

EAST HANOVER, N.J., April 12, 2007 /PRNewswire/ -- Investigators will begin offering Gleevec(R) (imatinib mesylate)* tablets to patients receiving placebo in a major North American clinical trial after an interim analysis showed participants with Kit-positive gastrointestinal stromal tumors treated with Gleevec following surgery were significantly less likely to experience a return of their cancer compared to those not taking this innovative therapy.

The interim analysis showed no recurrence of cancer in approximately 97% of patients given Gleevec for a year after surgery to remove tumors, compared to approximately 83% of those who underwent surgery but received a placebo. The investigators made these results public because the study had met its primary endpoint in terms of rate of recurrence-free survival.

The study involving more than 600 patients was sponsored by the National Cancer Institute (NCI), part of the US National Institutes of Health (NIH). It was conducted at multiple cancer centers in the US and Canada, and was led by the of Surgeons Oncology Group. Novartis supplied Gleevec for use in the study, and also provided partial funding under a Cooperative Research and Development Agreement with NCI to support the clinical development of Gleevec.

Gleevec has already been confirmed as an effective therapy in its approved use for patients with advanced metastatic or unresectable (inoperable) Kit- positive GIST. In a statement issued today by the NIH, the new findings were heralded as excellent news, with major implications for patients with primary disease.

"With these new data, we see that Gleevec may help patients with early GIST," said Diane Young, MD, Head of Global Medical Affairs at Novartis Oncology. "We will now work with the investig
'"/>




Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
2. Positive Aggrastat Results Featured in the Journal of the American College of Cardiology
3. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Protox Announces Positive Clinical Data from Prostate Cancer Study
5. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
6. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ESMO Conference
7. TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment
8. Positive ZIO-201 Interim Phase II Sarcoma Data Presented at European Society for Medical Oncology
9. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
10. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
11. Chi-Med Announces Positive Phase II Proof-of-Concept Data for HMPL-004 in Ulcerative Colitis
Post Your Comments:
(Date:8/28/2015)... According to a new market ... Prostate) Type (Protein & Genetic Biomarkers) Profiling Technology (Proteomics, ... Geography - Global Forecast to 2020", published by MarketsandMarkets, ... 17,689.0 Million USD by 2020 at a CAGR of ... Browse 191 Tables and 38 F ...
(Date:8/28/2015)... Research and Markets ( http://www.researchandmarkets.com/research/jq34zf/investigation ) ... on China,s Tobramycin Market, 2010-2019" report to their ... eye drop and ointment are the most common prescription ... caused by eye infection. Currently, dozens of enterprises in ... tobramycin, among which the Top 5 are s.a. Alcon- ...
(Date:8/28/2015)... Research and Markets ( ... "Investigation Report on China,s Insulin Aspart Market, ... Developed by Novo Nordisk, insulin aspart (under the ... for the treatment of diabetes. Compared with human ... analog, starts working fast and reports higher peak ...
Breaking Medicine Technology:Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 2Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 3Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 4Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 5Investigation Report on China's Tobramycin Market, 2015-2019 2China Insulin Aspart Market Report 2010-2019 - Developed by Novo Nordisk 2
... Oct. 31, 2011 Rock Creek Pharmaceuticals, a wholly owned ... today announced the second presentation of research findings related to ... a Tobacco Alkaloid, Ameliorates Disease in a Mouse Model of ... meeting of the American Thyroid Association in Indian Wells, CA ...
... SYDNEY, Oct. 31, 2011  To successfully irradiate a moving lung ... the tumor from moving or a means to compensate for ... Hospital Cancer Centre (Randwick, New South Wales) chose the second ... for the first time to treat a 75-year-old male patient ...
Cached Medicine Technology:Rock Creek Pharmaceuticals Announces Completion of Medical Conferences on Anatabloc™ Research, Comments on Research Presentation at American Thyroid Association Annual Meeting 2Rock Creek Pharmaceuticals Announces Completion of Medical Conferences on Anatabloc™ Research, Comments on Research Presentation at American Thyroid Association Annual Meeting 3Rock Creek Pharmaceuticals Announces Completion of Medical Conferences on Anatabloc™ Research, Comments on Research Presentation at American Thyroid Association Annual Meeting 4Australia's Prince of Wales Hospital Launches New Era of Targeted Lung Cancer Treatments with Elekta's Advanced 4D Motion Management Technology 2Australia's Prince of Wales Hospital Launches New Era of Targeted Lung Cancer Treatments with Elekta's Advanced 4D Motion Management Technology 3
(Date:8/29/2015)... ... , ... On September 30, 2015, the Career and Transfer Center (CTC) at ... Maricopa Community Colleges , will be hosting a Job Expo to provide a professional, ... , The Expo has expanded to much more than just a typical job and ...
(Date:8/29/2015)... Raleigh, NC (PRWEB) , ... August 29, 2015 ... ... about how mesothelioma develops, may extend and improve the lives of patients, according ... its website. Click here to read the full article. , The ...
(Date:8/29/2015)... ... August 29, 2015 , ... People who have heart or ... or asthma, are at higher risk from wildfire smoke especially in Calgary, Alberta.Those ... heart-rhythm problems (arrhythmia or irregular heartbeat) are also sensitive to air pollution. ...
(Date:8/28/2015)... Madre, CA (PRWEB) , ... August 28, 2015 ... ... solutions to wound center management, Decatur County Memorial Hospital recently transitioned management companies ... model of Wound Center Management for their outpatient wound center. , Transitioning ...
(Date:8/28/2015)... ... August 28, 2015 , ... With the goal of furthering music education ... year to the Adams County Fairgrounds in Mendon, IL on May 30th, 2015. Backed ... support music education in the underfunded school districts of Mendon and its neighboring town ...
Breaking Medicine News(10 mins):Health News:Estrella Mountain Community College Expo Offers ‘One-Stop’ for Employers and Students Seeking Internships, Jobs, Careers and Service Learning Opportunities 2Health News:Top Mesothelioma Researchers Highlight Targeted Therapies in New Report, According to Surviving Mesothelioma 2Health News:Heart Fit Clinic Sounds the Alarm on Forest Fire Smoke and Chronic Heart Disease in Calgary Area 2Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 2Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 3Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 4Health News:Best Drug Rehabilitation Interviews Country-Rock Duo Highway Run at the 2015 "Music With A Mission" Benefit Concert 2
... Sept. 24 The American Society of,Transplantation (AST) is ... to a unique target audience -- human resource professionals., ... of the Society of Human,Resource Management (SHRM) nationwide to ... program is designed to encourage,employers to adopt paid leave ...
... nationwide who have received 2008 New Innovator Awards ... are designed "to enable recipients to pursue exceptionally ... science." , The grants, which provide $1.5 million ... to Yuriy Kirichok, PhD, assistant professor of physiology, ...
... the Swiss Institute of,Bioinformatics in Berne, Switzerland, its director ... story". He said that he was,proud that as pioneers ... 25 working,groups was today able to announce the completion ... head of the SIB,s Swiss-Prot group said: "If human,DNA ...
... for People with Diabetes to Join,Him to Take the ... N.J., Sept. 24 Tony,Award-winning actor and Broadway star ... diabetes care, to launch Take the Stage,for Diabetes Awareness, ... diabetes about their condition. Since he was diagnosed,with type ...
... CHICAGO, Sept. 24 For the first ... a reproductive cancer, especially,ovarian and uterine (endometrial) ... a gynecologic oncologist. The 2008 State of ... to the Women of America,published by the ...
... Childhood ED ... Visits in US -, ROCKVILLE, ... a journey that parents dread making, but with,approximately 30 million children,s visits ... point in their lives. To help,parents and caregivers prepare, the Child Life ...
Cached Medicine News:Health News:AST to Address Human Resources Groups Nationwide to Encourage them to Adopt a Paid Leave Plan for Organ Donors 2Health News:2 UCSF scientists recognized for transformative research 2Health News:2 UCSF scientists recognized for transformative research 3Health News:Swiss Institute of Bioinformatics announces major breakthrough 2Health News:Swiss Institute of Bioinformatics announces major breakthrough 3Health News:Ben Vereen, Tony Award-Winning Actor, Strives to Raise Awareness of Diabetes and Treatment 2Health News:Ben Vereen, Tony Award-Winning Actor, Strives to Raise Awareness of Diabetes and Treatment 3Health News:Ovarian and Endometrial Cancer Patients Experience Improved Outcomes When Treated First by a Gynecologic Oncologist 2Health News:Ovarian and Endometrial Cancer Patients Experience Improved Outcomes When Treated First by a Gynecologic Oncologist 3Health News:Child Life Council Urges Parents to Think Ahead to Ease Child's Hospital Visit 2Health News:Child Life Council Urges Parents to Think Ahead to Ease Child's Hospital Visit 3Health News:Child Life Council Urges Parents to Think Ahead to Ease Child's Hospital Visit 4Health News:Child Life Council Urges Parents to Think Ahead to Ease Child's Hospital Visit 5Health News:Child Life Council Urges Parents to Think Ahead to Ease Child's Hospital Visit 6
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: