Navigation Links
Positive Results Prompt US National Cancer Institute to Make,Gleevec Available To Patients in Post-Surgical Gist Study

- Gleevec found to dramatically reduce the risk of cancer returning after surgery for Kit-positive gastrointestinal stromal tumors (GIST)

EAST HANOVER, N.J., April 12, 2007 /PRNewswire/ -- Investigators will begin offering Gleevec(R) (imatinib mesylate)* tablets to patients receiving placebo in a major North American clinical trial after an interim analysis showed participants with Kit-positive gastrointestinal stromal tumors treated with Gleevec following surgery were significantly less likely to experience a return of their cancer compared to those not taking this innovative therapy.

The interim analysis showed no recurrence of cancer in approximately 97% of patients given Gleevec for a year after surgery to remove tumors, compared to approximately 83% of those who underwent surgery but received a placebo. The investigators made these results public because the study had met its primary endpoint in terms of rate of recurrence-free survival.

The study involving more than 600 patients was sponsored by the National Cancer Institute (NCI), part of the US National Institutes of Health (NIH). It was conducted at multiple cancer centers in the US and Canada, and was led by the of Surgeons Oncology Group. Novartis supplied Gleevec for use in the study, and also provided partial funding under a Cooperative Research and Development Agreement with NCI to support the clinical development of Gleevec.

Gleevec has already been confirmed as an effective therapy in its approved use for patients with advanced metastatic or unresectable (inoperable) Kit- positive GIST. In a statement issued today by the NIH, the new findings were heralded as excellent news, with major implications for patients with primary disease.

"With these new data, we see that Gleevec may help patients with early GIST," said Diane Young, MD, Head of Global Medical Affairs at Novartis Oncology. "We will now work with the investig
'"/>




Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
2. Positive Aggrastat Results Featured in the Journal of the American College of Cardiology
3. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Protox Announces Positive Clinical Data from Prostate Cancer Study
5. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
6. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ESMO Conference
7. TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment
8. Positive ZIO-201 Interim Phase II Sarcoma Data Presented at European Society for Medical Oncology
9. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
10. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
11. Chi-Med Announces Positive Phase II Proof-of-Concept Data for HMPL-004 in Ulcerative Colitis
Post Your Comments:
(Date:3/27/2015)... WINNIPEG , March 27, 2015 /PRNewswire/ - Medicure ... Board of Directors has approved the grant of an ... management company employees and consultants of the Company pursuant ... 181,070 are set to expire on the tenth anniversary ... expire on the third anniversary of the date of ...
(Date:3/27/2015)... , March 27, 2015 /CNW Telbec/ - Russell ... Research-Based Pharmaceutical Companies (Rx&D), welcomes the 2015-2016 Quebec Budget, ... working group on the biopharmaceutical industry. However, the association ... "We commend the government,s intent to strive ... of measures to promote Quebec,s ...
(Date:3/27/2015)... March 27, 2015 Biopharmaceutical Industry Leads ... industry comes out on top as the country,s manufacturing ... new report  from ndp│analytics. According to the  analysis , ... investment over the last decade, accounting for 27 percent ... A Short Video on Medicare Part D ...
Breaking Medicine Technology:Quebec 2015-2016 Budget: Rx&D welcomes fiscal discipline and biopharma working group, but the decrease in government spending on medicines is questioned 2Quebec 2015-2016 Budget: Rx&D welcomes fiscal discipline and biopharma working group, but the decrease in government spending on medicines is questioned 3Week in Review: The Latest from PhRMA 2
... NEW YORK, Oct. 25, 2011 Reportlinker.com ... is available in its catalogue: ... http://www.reportlinker.com/p090623/Global-Eyeglasses-Industry.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Ophthalmic_Devices This report ... Million Units and US$ Million by the ...
... SAN DIEGO, Oct. 25, 2011 Aethlon ... developing therapeutic filtration devices to address infectious disease ... A. Joyce will present a company overview, discuss ... medical device partnering conference: Investment-In-Innovation (IN3) SUMMIT on ...
Cached Medicine Technology:Global Eyeglasses Industry 2Global Eyeglasses Industry 3Global Eyeglasses Industry 4Global Eyeglasses Industry 5Global Eyeglasses Industry 6Global Eyeglasses Industry 7Global Eyeglasses Industry 8Global Eyeglasses Industry 9Global Eyeglasses Industry 10Global Eyeglasses Industry 11Global Eyeglasses Industry 12Global Eyeglasses Industry 13Aethlon Medical to Present at IN3 Medical Innovation Summit on October 27th 2
(Date:3/28/2015)... 28, 2015 Take a bite of ... into action. Acids tumble into the stomach, ready to ... valve-like structure lets these acids run amok, triggering a ... common symptom. More than 60 million Americans have heartburn ... where heartburn starts, and how it can be stopped. ...
(Date:3/28/2015)... March 28, 2015 Emergency Medical Care ... care in Manhattan, recently commemorated its three-year anniversary of ... Manhattan. In addition to 24-hour urgent care, Emergency Medical ... , At this time, Emergency Medical Care’s Urgent ... asthma, chest pain, eye injuries, ear infections, fevers, insect ...
(Date:3/28/2015)... 28, 2015 Pitching speed, player’s height, and ... shoulder and elbow injuries, according to new research released today ... ) Specialty Day. , “Our findings indicate that a 10 ... in likelihood of a history of injury, a 10 mile ... increase likelihood of a history of injury, and playing for ...
(Date:3/28/2015)... Las Vegas, NV (PRWEB) March 28, 2015 ... option for patients with Type V AC joint injuries, ... The study, presented today at the American Orthopaedic Society ... military personnel returned to duty faster when surgery was ... 24 patients, with 7 receiving surgical treatment and 17 ...
(Date:3/28/2015)... March 28, 2015 Aureus Medical ... staffing, including physical therapy jobs, has announced that ... Ohio Physical Therapy Association Annual Conference to be ... Downtown Hotel in Columbus, OH. , The ... and exhibits with products and services. , ...
Breaking Medicine News(10 mins):Health News:Bypass Your Heartburn Worries This Easter With Tylers Coffee 2Health News:Emergency Medical Care Celebrates Three Years of 24/7 Walk-In Urgent Care Services 2Health News:Researchers Highlight Shoulder and Elbow Injury Possibility in Youth Players 2Health News:For Type V AC Joint Injuries, Early Surgery May Not Be the Best Approach 2Health News:Healthcare Staffing Leader, Aureus Medical Group, to Exhibit at the Ohio Physical Therapy Association Annual Conference 2
... of ,Proud to be GI Awards, Honored for Commitment to Patient ... ... 26 Today, Procter and Gamble,Pharmaceuticals (P&G) is encouraging GI and Endoscopy ... patients through its support of the Society of Gastroenterology,Nurses and Associates, Inc. ...
... The apples and apple juice you consume may have ... in the body in the colon. New ... apple juice components actually enhance biological mechanisms that produce ... Using human fecal matter as the test substance, German ...
... March 26, 2008 Silver Spring, MD: Artemisinins in Malaria Therapy, ... Milhous, and Dr. (COL) Peter J. Weina (Division of Experimental ... overview of the historical use and recent developments in the ... the most prevalent scourges of mankind malaria. , WRAIR, ...
... Launches Totally Light2Go(TM) Vitamin Stix Drink Mix, BROOKLYN, ... way to take your vitamins, 4C Totally Light2Go(TM) Vitamin ... on-the-go drink,mixes are quickly becoming a staple for the ... indulge as all three flavors of the 4C,Totally Light2Go(TM) ...
... ... -, - Removal of the Going Concern Qualification by its Independent Registered ... Public Accountants - - ... XELR8 Holdings, Inc. (Amex:,BZI), a provider of functional foods, beverages and nutritional,supplements, today announced its financial ...
... China, March 26 /Xinhua-PRNewswire-FirstCall/ -- Linkwell,Corporation ... leading developer,manufacturer and distributor of healthcare ... its wholly owned subsidiary Shanghai LiKang,Disinfection ... agreement with Shanghai,Disinfection Association (SDA), to ...
Cached Medicine News:Health News:Nationwide Awards Recognize Nurses, Associates and Nursing Teams That Specialize in Gastroenterology and Endoscopy 2Health News:Nationwide Awards Recognize Nurses, Associates and Nursing Teams That Specialize in Gastroenterology and Endoscopy 3Health News:WRAIR investigators pioneering work on an exciting new class of antimalarial compounds 2Health News:Flavor and Vitamins on the Go 2Health News:XELR8 Holdings Announces Fiscal 2007 Financial Results 2Health News:XELR8 Holdings Announces Fiscal 2007 Financial Results 3Health News:XELR8 Holdings Announces Fiscal 2007 Financial Results 4Health News:XELR8 Holdings Announces Fiscal 2007 Financial Results 5Health News:XELR8 Holdings Announces Fiscal 2007 Financial Results 6Health News:XELR8 Holdings Announces Fiscal 2007 Financial Results 7Health News:XELR8 Holdings Announces Fiscal 2007 Financial Results 8Health News:Shanghai Disinfection Association and Linkwell Corporation Co-Establish the 'Shanghai Disinfection Association Laboratory Center' 2Health News:Shanghai Disinfection Association and Linkwell Corporation Co-Establish the 'Shanghai Disinfection Association Laboratory Center' 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: