Navigation Links
Poniard Pharmaceuticals Announces Promising Data From Interim,Safety Analysis of Phase 1 Combination Trials of Picoplatin in,Colorectal and Prostate Cancers

- Company Planning to Initiate Phase 2 Trials in Colorectal Cancer and in Hormone-Refractory Prostate Cancer in Q307 -

SOUTH SAN FRANCISCO, Calif., June 01, 2007 /PRNewswire-FirstCall/ -- Poniard Pharmaceuticals, Inc. , a biopharmaceutical company focused on oncology, today announced promising results from an interim safety analysis of two Phase 1 dose-escalating trials of picoplatin, a new generation platinum for the potential first-line treatment of metastatic colorectal cancer (CRC) and metastatic hormone-refractory prostate cancer (HRPC). Initial safety data from the Phase 1 trial in CRC demonstrated that picoplatin can be safely administered with fluorouracil and leucovorin, and initial safety data from the Phase 1 trial in HRPC demonstrated that picoplatin can be safely combined with the dose of docetaxel (Taxotere(R)) used in current practice for HRPC.

The data were included in abstracts published in the 2007 American Society of Clinical Oncology (ASCO) Annual Meeting Proceedings.

    -- Abstract #14510. Gladkov Jr O, Manikhas G, Biakhov M, Tjulandin S,

       Karlin D. Phase 1 study of picoplatin in combination with 5-

       fluorouracil and leucovorin as initial therapy in subjects with

       metastatic colorectal cancer.

    -- Abstract #15546. Roman L, Karlov P, Kaprin A, Gladkov Jr O, Breitz H.

       Phase 1 study of picoplatin and docetaxel with prednisone in patients

       with chemotherapy-naïve metastatic hormone refractory prostate cancer.


"Our new data indicate that picoplatin can be safely combined with established cancer therapeutics. In 66 patients treated up to 10 months, we have observed reversible myelosuppression that is non-cumulative and has not led to any treatment-related mortality," said Jerry McMahon, Ph.D., chairman and CEO of Poniard. "These Phase 1 studies have explored different doses of picoplatin and different dosing schedu
'"/>




Page: 1 2 3 4 5 6

Related medicine technology :

1. Poniard Pharmaceuticals Announces Clinical Data from Picoplatin Phase 2 Small Cell Lung Cancer Trial To Be Presented at American Society of Clinical Oncology Annual Meeting
2. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
3. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
5. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
6. Sunesis Pharmaceuticals to Present at the C. E. Unterberg, Towbin Emerging Growth Conference
7. EPIX Pharmaceuticals to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
8. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
9. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
10. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
11. Cyclacel Pharmaceuticals Announces Results of Phase II Seliciclib Combination Studies
Post Your Comments:
(Date:5/27/2015)... Delaware , May 27, 2015 ... corporation engaged in the development and commercialization ... new and novel electrotherapy for the noninvasive treatment of ... May 19, 2015, Zacks Small Cap Research http://scr.zacks.com ... here . According to Zacks, research update, E-QURE ...
(Date:5/27/2015)... N.J. , May 27, 2015  The ... LLC, utilizes a Motion Systems Corporation ball drive ... freedom. Motion Systems manufactures the industry,s largest selection ... to a wide array of industries, including medical ... help people who are wheelchair-bound as well as ...
(Date:5/27/2015)... SINGAPORE , LONDON and ... - http://www.abmrg.com/Indonesia-Respiratory-Devices-and-Respiratory-Diagnostics-Market-through-2020---Detailed-analysis-of-Hospital-and-Retail-market.html ... smokers - Around 400,000 Indonesians die annually ... smokers - Three-fourths of 6.5 million vehicles ... the emission test Indonesia ...
Breaking Medicine Technology:Zacks Investment Small Cap Research Issues Quarterly Update on E-QURE 2Zacks Investment Small Cap Research Issues Quarterly Update on E-QURE 3Innovative Technology Liberates the Wheelchair-Bound 2Indonesia Respiratory Devices Market is Expected to Grow at a CAGR of 9% - Boosting Growth for Respiratory Disposables 2Indonesia Respiratory Devices Market is Expected to Grow at a CAGR of 9% - Boosting Growth for Respiratory Disposables 3Indonesia Respiratory Devices Market is Expected to Grow at a CAGR of 9% - Boosting Growth for Respiratory Disposables 4
(Date:5/27/2015)... (PRWEB) May 27, 2015 Difass USA, ... in the U.S. with its first three flagship products, ... for purchase nationwide through http://www.difassusa.com . , ... health and productivity, but some people struggle with getting ... Dormiva™ is a sleep aid designed to help you ...
(Date:5/27/2015)... Tx (PRWEB) May 27, 2015 ... germline pharmacogenomic and somatic genomic analysis in personalized cancer ... published by the American Society of Clinical Oncology (ASCO) ... June 2 in Chicago. , The molecular and clinical ... Cancer Genome Atlas (TCGA) database. The study reports improved ...
(Date:5/27/2015)... 2015 Coco Libre announced today that artists ... reach for Organic Coconut Water to quench their thirst during ... at VIP areas, artist greenrooms, corporate skyboxes and concessions areas ... hotels and on festival shuttle buses. , “We’re excited ... Noa Elan, Director of Strategic Partnerships for Latitude 38 Entertainment, ...
(Date:5/27/2015)... May 27, 2015 On June 5, ... agency, will partner with LifeSource to host Donate Your ... take place in a LifeSource donor coach outside of ... 4:00 p.m. , Demand for whole blood units is ... during the summer months. LifeSource requires approximately 1,000 donations ...
(Date:5/27/2015)... Cincinnati Veterans Affairs Women’s Health Clinic in ... Foundation is proud to host the first annual Women Veterans ... 11 at the Freedom Center from 6 p.m. to 10 ... emcee. , This event honors and celebrates women tri-state ... The banquet is free to the first 150 women Veterans ...
Breaking Medicine News(10 mins):Health News:Supplement Brand Difass USA Launches in the U.S. with Three Flagship Products Designed to Bring Balance Back to Your Life 2Health News:CompanionDx® Analyzes Non-small Cell Lung Cancer Data for Personalized Cancer Therapy 2Health News:CompanionDx® Analyzes Non-small Cell Lung Cancer Data for Personalized Cancer Therapy 3Health News:Coco Libre Puts Organic Coconut Water on the Line-up at BottleRock Napa 2Health News:Donate Your Break and Save Lives at the River North Blood Drive 2Health News:Cincinnati VA Women’s Health Clinic Celebrates Women Veterans at Awards Banquet 2
... Tools & Functional Architecture Dynamically Render Personalized Care for ... Mass. and SAN DIEGO, June 3 Casenet, Inc., ... unveiled TruCare(TM) 4.0, its next generation care management software ... years of exclusive care management software development specifically for ...
... breathing, researchers say , WEDNESDAY, June 3 (HealthDay News) ... have sleep-disordered breathing, a condition that,s associated with behavioral ... research shows. , In the study, researchers examined 700 ... chosen from 18 public elementary schools in Pennsylvania. Each ...
... Food & Drug Stores donated $837,043.00 to Primary Children,s Medical ... over the past several weeks. , , Smith,s ... been hosting a variety of fundraising events like hot dog ... raise money for the children,s hospital. Smith,s customers, associates and ...
... ... 28 - 30th in Chicago, IL USA and IntertechPira,s green alternative to the paper ... Portland, ... 2009 conference and exhibit, taking place September 28 - 30, 2009 at the Embassy ...
... gift-giving strategy if you,re a woman trying to figure out how to ... give him the gift you really want for yourself. , , ... , OK, that probably rules out the ,65 Mustang and the even-bigger ... best present for millions of women - one that would actually be ...
... Health insurer chooses Cincom Eloquence to streamline policy generation ... provider Cincom Systems announces that Medica ( www.medica.com ... more than 1.5 million members, has chosen Cincom Eloquence(R) ... automation processes. , , Key considerations for Medica,s ...
Cached Medicine News:Health News:Casenet Unveils TruCare 4.0 - New Care Management Platform Delivers Personalized, Member-Centric Care 2Health News:Casenet Unveils TruCare 4.0 - New Care Management Platform Delivers Personalized, Member-Centric Care 3Health News:Many Overweight Kids Not Getting a Good Night's Sleep 2Health News:Smith's Donates $837,000 to Primary Children's Medical Center in Utah 2Health News:Biopolymers Symposium 2009 Announces Final Program and Interactive Green Brochure 2Health News:Perfect Father's Day Gift: The Sound of Silence 2Health News:Perfect Father's Day Gift: The Sound of Silence 3Health News:Medica Selects Cincom's Document Automation Software 2Health News:Medica Selects Cincom's Document Automation Software 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: