Navigation Links
Poniard Pharmaceuticals Announces Promising Data From Interim,Safety Analysis of Phase 1 Combination Trials of Picoplatin in,Colorectal and Prostate Cancers

- Company Planning to Initiate Phase 2 Trials in Colorectal Cancer and in Hormone-Refractory Prostate Cancer in Q307 -

SOUTH SAN FRANCISCO, Calif., June 01, 2007 /PRNewswire-FirstCall/ -- Poniard Pharmaceuticals, Inc. , a biopharmaceutical company focused on oncology, today announced promising results from an interim safety analysis of two Phase 1 dose-escalating trials of picoplatin, a new generation platinum for the potential first-line treatment of metastatic colorectal cancer (CRC) and metastatic hormone-refractory prostate cancer (HRPC). Initial safety data from the Phase 1 trial in CRC demonstrated that picoplatin can be safely administered with fluorouracil and leucovorin, and initial safety data from the Phase 1 trial in HRPC demonstrated that picoplatin can be safely combined with the dose of docetaxel (Taxotere(R)) used in current practice for HRPC.

The data were included in abstracts published in the 2007 American Society of Clinical Oncology (ASCO) Annual Meeting Proceedings.

    -- Abstract #14510. Gladkov Jr O, Manikhas G, Biakhov M, Tjulandin S,

       Karlin D. Phase 1 study of picoplatin in combination with 5-

       fluorouracil and leucovorin as initial therapy in subjects with

       metastatic colorectal cancer.

    -- Abstract #15546. Roman L, Karlov P, Kaprin A, Gladkov Jr O, Breitz H.

       Phase 1 study of picoplatin and docetaxel with prednisone in patients

       with chemotherapy-naïve metastatic hormone refractory prostate cancer.


"Our new data indicate that picoplatin can be safely combined with established cancer therapeutics. In 66 patients treated up to 10 months, we have observed reversible myelosuppression that is non-cumulative and has not led to any treatment-related mortality," said Jerry McMahon, Ph.D., chairman and CEO of Poniard. "These Phase 1 studies have explored different doses of picoplatin and different dosing schedu
'"/>




Page: 1 2 3 4 5 6

Related medicine technology :

1. Poniard Pharmaceuticals Announces Clinical Data from Picoplatin Phase 2 Small Cell Lung Cancer Trial To Be Presented at American Society of Clinical Oncology Annual Meeting
2. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
3. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
5. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
6. Sunesis Pharmaceuticals to Present at the C. E. Unterberg, Towbin Emerging Growth Conference
7. EPIX Pharmaceuticals to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
8. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
9. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
10. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
11. Cyclacel Pharmaceuticals Announces Results of Phase II Seliciclib Combination Studies
Post Your Comments:
(Date:4/30/2015)...  DURECT Corporation (Nasdaq: DRRX ) announced today ... revenues were $4.8 million and net loss was $4.9 ... as compared to total revenues of $6.3 million and ... ended March 31, 2014.At March 31, 2015, we had ... and investments of $34.9 million at December 31, 2014.  ...
(Date:4/30/2015)... -- Pharmacists at Osco Drug have voted to become members ... . The newly organized group consists of 20 pharmacists ... throughout Maine . "We ... them the powerful representation that Teamsters Local 340 can bring ... Local 340. "We will work tirelessly, providing them with the ...
(Date:4/30/2015)... , April 30, 2015  Isis Pharmaceuticals, Inc. ... earned a $10 million milestone payment from Biogen ... to treat a neurological disorder.  This is the ... in development, under Isis, and Biogen,s broad strategic ... treat neurological and neuromuscular disorders.  ...
Breaking Medicine Technology:DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 2DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 3DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 4DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 5DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 6DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 7DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 8DURECT Corporation Announces First Quarter 2015 Financial Results and Update of Programs 9Isis Pharmaceuticals Earns $10 Million Milestone Payment From Biogen 2Isis Pharmaceuticals Earns $10 Million Milestone Payment From Biogen 3
(Date:5/2/2015)... 02, 2015 On Tuesday April 7th, ... (ELCH) gathered to celebrate improvements in patient care. In ... Partners (RVHP), had zero acquired ventilator associated infections, zero ... infections. ELCH was also recently named a Top Performer ... at ELCH credited the teamwork of staff from all ...
(Date:5/2/2015)... ZoomCare, the Portland-based innovator of on-demand healthcare ... its new healthcare insurance to individuals and small businesses ... System is the nation’s first health insurance system built ... Personal Health Insurance was ZoomCare’s first such filing including ... to review and regulation by the Oregon Insurance Division. ...
(Date:5/1/2015)... Caicos Islands, BWI (PRWEB) May 02, 2015 ... website! It is http://www.thevenetiangracebay.com , and it ... it incorporates the stunning white and attractive turquoise hues ... study of Google, sixty seven percent of leisure travelers ... study showed that smartphones were used in the planning ...
(Date:5/1/2015)... 01, 2015 Royal River Natural Foods, ... reports on a new study that found two natural ... and improved physical function as well as standard drug ... of the knee. , The report is part of ... Well Being® ,” which Royal River Natural Foods publishes ...
(Date:5/1/2015)... DC (PRWEB) May 01, 2015 It’s raining ... and House introducing proposals to expand federal support for telemedicine. ... years that ATA has been working with Congress,” said Jonathan ... actions signify how the nation is poised to embrace the ... is one more step in fulfilling ATA’s mission to improve ...
Breaking Medicine News(10 mins):Health News:East Liverpool City Hospital Celebrates Patient Care Improvements 2Health News:ZoomCare Applies to be on Oregon Exchange 2Health News:Turks and Caicos Resort, The Venetian on Grace Bay, Launches New Web Presence 2Health News:New Study Finds Nutrients Ease Arthritis Pain, Retailer Reports 2Health News:ATA: Congress Floods the Halls with Telemedicine Proposals 2
... (Nasdaq: ALTH ) today announced the appointment ... this position, Mr. Bennett,will lead the Company,s manufacturing ... of Allos, product candidates., "We are delighted ... Berns,President and CEO. "Bruce,s experience in all aspects ...
... Jan. 28 In a reversal of what has,become ... online interactive training coupled with two hours of live ... all EZM Web,customers., EZM Web tracks and controls ... vehicle plus inventory control via the Web. It is ...
... (NYSE: NTY ), (http://www.NBTY.com ), a leading global ... the fiscal first quarter ended,December 31, 2007., For ... sales were,$511 million compared to $506 million for the ... $5 million or 1%., Net income for the ...
... Advocates for Women,s Health and Rights call for an ... Government Funding for Failed Abstinence-Only Programs, NEW ... Sexuality Information and Education Council of the United States,(SIECUS) ... will hold,panel discussions at Bowdoin College (January 29) and ...
... Shazaaam! LLC, an integrated,marketing communications agency headquartered ... and Marketing Communications Agency of,Record for Enuresis ... social marketing, proactive and reactive,blogging, traditional and ... and visibility among its target market., ...
... of caffeine in coffee, tea or soft drinks increases ... and may undermine efforts to control their disease, say ... new technology that measured participants glucose (sugar) levels on ... a psychologist at Duke and the lead author of ...
Cached Medicine News:Health News:Allos Therapeutics Appoints Bruce K. Bennett as Vice President, Manufacturing 2Health News:Allos Therapeutics Appoints Bruce K. Bennett as Vice President, Manufacturing 3Health News:Maintenance Software Company Bucks Trend, Offers Unlimited No-Charge Product Tech Support 2Health News:NBTY Reports First Quarter Results 2Health News:NBTY Reports First Quarter Results 3Health News:NBTY Reports First Quarter Results 4Health News:NBTY Reports First Quarter Results 5Health News:NBTY Reports First Quarter Results 6Health News:NBTY Reports First Quarter Results 7Health News:NBTY Reports First Quarter Results 8Health News:NBTY Reports First Quarter Results 9Health News:NBTY Reports First Quarter Results 10Health News:NBTY Reports First Quarter Results 11Health News:NBTY Reports First Quarter Results 12Health News:NBTY Reports First Quarter Results 13Health News:NBTY Reports First Quarter Results 14Health News:Harm of Abstinence-Only Programs in U.S. and Abroad Subject of Panel Discussion at Two Maine College Campuses 2Health News:Harm of Abstinence-Only Programs in U.S. and Abroad Subject of Panel Discussion at Two Maine College Campuses 3Health News:Shazaaam! Named PR Agency of Record for Enuresis Treatment Center 2Health News:Cutting caffeine may help control diabetes 2
Cushing Flat Drill, only Component Parts and Accessories for HUDSON Cranial Drill. 14 mm...
Hudson brace only. Component parts and accessories for Hudson cranial drill....
Greenberg micro instrument holder is a flexbar arm used to hold micro instruments used repeatedly within retracted fields. Holds instruments with shafts up to 1/8 in diameter....
Length-9 (229 mm) Tapered retractor blades....
Medicine Products: