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Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results

, the plasma moves into the reaction chamber and reacts with fluorescent-conjugated antibodies to all three markers. After incubation, the sample-reagent mixture flows through the device detection lane where complexes of analyte and conjugates are captured. The level of fluorescence is directly proportional to the concentration of the analyte. The device is read in the Triage MeterPlus, which is a multifunctional reader also utilized for other Triage assays. The test yields simultaneous results for all three markers in approximately 15 minutes. Data can be managed using Triage Census data management software and uploaded quickly to laboratory information systems. The system contains both internal and external quality controls that are user-friendly. The reader is compact and portable, with a self-contained power source.

Response Biomedical Corp. offers the RAMP Cardiac Marker System, with separate test kits for CK-MB, myoglobin and troponin I. It is also a quantitative immunofluorescence assay for EDTA whole blood specimens. To perform the test, a diluted blood sample is added to the sample well of the test cartridge, the red blood cells are retained, and the plasma migrates. Fluorescent-dyed latex particles coated with antigen specific antibodies bind to antigen in the sample. Antigen-bound particles are captured in the detection zone and excess particles are captured at the internal control zone by anti-immunoglobins. The fluorescence of the detection and internal control zones is measured by the RAMP Clinical Reader, which is a multifunctional reader utilized for the RAMP platform technology. The ratio of the values is calculated and the analyte is quantified by interpolation from a lot-specific standard curve supplied in the test kit. The tests for CK-MB and Troponin I yield results in 10 and 12 minutes respectively. Data can be uploaded quickly to laboratory information systems. The reader is compact and portable, with a self-contained p
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