Navigation Links
Pivotal Phase III Trial Showed Promacta (eltrombopag olamine),Raised Platelet Counts and Reduced Bleeding in Patients With,Chronic ITP

p>

ITP is characterized by increased autoimmune platelet destruction and/or inadequate platelet production. Its cause is currently unknown. Some patients with ITP are asymptomatic or have mild bruising while others develop more serious bleeding that can be life-threatening.(6) A normal blood platelet count is greater than or equal to 150,000/microliter and less than or equal to 400,000/microliter.(7) A reduction in platelet count (to a level <150,000/microliter) is the defining characteristic of any type of thrombocytopenia which can be confirmed following a routine blood test. An endpoint of 50,000/microliter was selected because at a platelet count of <50,000/microliter there is a higher risk of developing bleeding complications from low platelet counts. At a platelet count of >50,000/microliter there is a lower risk of bleeding and bruising. This is consistent with products previously approved to treat ITP and is considered as a target platelet count in ITP treatment guidelines.(8)

Other Forms of Thrombocytopenia

Thrombocytopenia can occur as a consequence of an autoimmune abnormality, bone marrow insufficiency, chemotherapy treatment, interferon treatment, viral infection or chronic liver disease.(9,10) Thrombocytopenia can impede a variety of diagnostic and/or medical treatments. It can prevent cancer patients from receiving their full dose of chemotherapy on schedule, preclude patients with hepatitis C infection from receiving interferon therapy or lead to dose reductions or discontinuation of therapy, and complicate surgical or dental procedures.(11,12)

About GlaxoSmithKline

GlaxoSmithKline -- one of the world's leading research-based pharmaceutical and healthcare companies -- is committed to improving the quality of human life by enabling people to do more, feel better, and live longer. For company information, visit GlaxoSmithKline at http://www.gsk.com.

For further inf
'"/>




Page: 1 2 3 4 5 6

Related medicine technology :

1. NexMed Announces Completion of Patient Enrollment in Two Pivotal Phase 3 Studies for Anti-Fungal Product
2. Advanced Life Sciences Announces Supplemental Efficacy Data from First Pivotal Phase 3 Pneumonia Clinical Trial
3. Based on Up to 6 Years of Follow-Up, Biovest Announces Favorable Interim Blinded Data for Fast-Tracked Pivotal Phase 3 Clinical Trial of BiovaxID Anti-Cancer Vaccine for Non-Hodgkins Lymphoma
4. Accentia Biopharmaceuticals Announces Favorable Interim Blinded Data on SinuNase in Its Fast-Tracked Pivotal Phase 3 Clinical Trial for Chronic Sinusitis
5. Novagali Pharma Presents at AACO the Results of its Pivotal Phase III Clinical Trial of Vekacia in Children Suffering From Vernal Keratoconjunctivitis
6. Cethromycin Achieves Primary Endpoint in Pivotal Phase 3 Pneumonia Clinical Trial
7. Javelin Pharmaceuticals Announces Successful Pivotal Phase 3 Trial Data
8. Organons Sugammadex Demonstrated a 9-12 Times Faster Recovery in Phase III Pivotal Trial as Compared to Neostigmine
9. Organons Sugammadex Demonstrated a 9-12 Times Faster Recovery in Phase III Pivotal Trial Compared to Neostigmine
10. Updated Overall Survival Data From Pivotal Herceptin Adjuvant Studies in HER2-Positive Breast Cancer
11. GenVec Announces Update of Safety and Efficacy Data from Pivotal Phase II/III PACT Study of TNFerade at ASCO
Post Your Comments:
(Date:1/22/2015)... Jan. 22, 2015 /PRNewswire/ - Pivotal Therapeutics Inc. (OTCQX:PVTTF; CSE:PVO), ("Pivotal" ... on Omega-3 therapies for cardiovascular disease and overall health is ... accomplishments in 2014 and its outlook for 2015 from the ... Shareholders, We would like to take this opportunity ...
(Date:1/22/2015)...  Bio-Techne Corporation (NASDAQ: TECH ) announced today ... the new Simple Plex platform through its Proteins Platform ... re-branding of the previously acquired CyPlex instrument platform from ... transformative immunoassay technology which integrates an innovatively designed microfluidic ...
(Date:1/22/2015)... 2015 Increasing sophistication among enterprise buyers of language ... in 2015, says Moravia CMO, Renato ... by market research firm Common Sense Advisory, 15 percent ... translation and localization needs. "From a language industry perspective, ...
Breaking Medicine Technology:Pivotal Therapeutics: Year in Review and CEO Update 2Pivotal Therapeutics: Year in Review and CEO Update 3Pivotal Therapeutics: Year in Review and CEO Update 4Pivotal Therapeutics: Year in Review and CEO Update 5Pivotal Therapeutics: Year in Review and CEO Update 6Pivotal Therapeutics: Year in Review and CEO Update 7Bio-Techne Launches Simple Plex Platform 2Bio-Techne Launches Simple Plex Platform 3Moravia Sees Single-Sourcing as Key Localization Trend in 2015 2
... 29, 2011 Laboratory Supply Company (LABSCO), the largest ... products to hospitals, physician office laboratories, reference labs and ... to expand its executive leadership team with the new ... financial officer. Willett,s career has included over ...
... 2011 Masimo (NASDAQ: ... & Welfare (MHLW) and Health Canada regulatory clearances of Masimo ... conveniently measure total hemoglobin (SpHb®), SpO2, perfusion index, and pulse ... Hemoglobin is one of the most commonly ordered tests in ...
Cached Medicine Technology:LABSCO Hires George Willett as New Vice President and Chief Financial Officer 2Masimo Pronto-7™ Receives Japanese and Canadian Regulatory Clearances 2Masimo Pronto-7™ Receives Japanese and Canadian Regulatory Clearances 3Masimo Pronto-7™ Receives Japanese and Canadian Regulatory Clearances 4Masimo Pronto-7™ Receives Japanese and Canadian Regulatory Clearances 5
(Date:1/22/2015)... Deer Path of Huntley -- a ... Happy Hour from 3 p.m. to 4 p.m. on Feb. 13. ... Huntley, Illinois, serves adults with physical disabilities between the ages of ... Day treats, games and sweetheart-themed karaoke. , For more information about ...
(Date:1/22/2015)... January 22, 2015 Woodloch Pines, an ... been selected by TripAdvisor as the number one best large ... best in the world for their annual Travelers’ Choice Awards. ... community . The website is home to millions of unbiased ...
(Date:1/22/2015)... 23, 2015 Angelweddingdress is a famous wedding ... its customers to follow it on Facebook, Twitter, and Pinterest. ... Day gift. Angelweddingdress draws a lottery every week. , Moreover, ... Feb. 28, 2015. Click Angelweddingdress homepage for more ...
(Date:1/22/2015)... TX (PRWEB) January 22, 2015 A ... issue of experience and person-centeredness in the long-term care ... towards action across the continuum. The paper, “The Power ... Continuum,” engages perspectives and practices of the patient, resident ...
(Date:1/22/2015)... Joan Lunden, award-winning American journalist, beloved television host, ... 32nd Annual Miami Breast Cancer Conference planned and ... , shares that “a fast-growing, virulent” cancer in her ... not followed up her clean mammogram with an ultrasound. ...
Breaking Medicine News(10 mins):Health News:Deer Path of Huntley Affordable Assisted Living to Host Valentine's Day Happy Hour 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 3Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6
... generic drug names. Unregulated continuing medical education ... of the strategies used by some in the ... doctors, according to a Georgetown University Medical Center ... at increasing physician access to unbiased information about ...
... Veteran Will Focus on Broader Product Distribution, Revenue ... DecisionView, Inc., the leading provider of Clinical Optimization ... that its Board of Directors has appointed James ... and CEO of DecisionView, effective immediately. Most recently, ...
... Nearly 60% of Americans Age 40 to 79 ... Loss, Divorce, Death of a Spouse or Major ... Affected Both Financially and EmotionallyAARP Financial Inc. President ... to Successfully Managing Your Finances in a Life ...
... 31 Conseco, Inc. (NYSE: CNO ), reported today that it ... made to the credit agreement include:, , ... June 30, 2010 to 32.5%, returning to 30% thereafter; , ... June 30, 2010, returning to 2.0x thereafter; , ...
... a series of informational custom printing product videos. The laser membership ... insights into the product uses, materials and options. , ... ... membership cards video includes a quality mix of visuals supported by ...
... Through Simple IngredientsLA JOLLA, Calif., March 31 ... announced the launch of Island Vanilla(TM), a wheat ... to create a wholesome, naturally sweet breakfast paradise.(Logo: ... unique flavor that Island Vanilla brings ...
Cached Medicine News:Health News:GUMC researcher creates first Web-interactive CME course for physicians on pharmaceutical marketing 2Health News:GUMC researcher creates first Web-interactive CME course for physicians on pharmaceutical marketing 3Health News:DecisionView Board of Directors Appoints James P. Scullion as CEO and President 2Health News:AARP Financial Inc. Survey Finds: Vast Majority of Families Struggle With Financial Implications of a Life Crisis 2Health News:AARP Financial Inc. Survey Finds: Vast Majority of Families Struggle With Financial Implications of a Life Crisis 3Health News:AARP Financial Inc. Survey Finds: Vast Majority of Families Struggle With Financial Implications of a Life Crisis 4Health News:AARP Financial Inc. Survey Finds: Vast Majority of Families Struggle With Financial Implications of a Life Crisis 5Health News:AARP Financial Inc. Survey Finds: Vast Majority of Families Struggle With Financial Implications of a Life Crisis 6Health News:AARP Financial Inc. Survey Finds: Vast Majority of Families Struggle With Financial Implications of a Life Crisis 7Health News:Conseco Closes Amendment to Credit Facility 2Health News:Conseco Closes Amendment to Credit Facility 3Health News:Conseco Closes Amendment to Credit Facility 4Health News:My1Stop.com Launches Suite of Online Custom Printing Videos Beginning with Laser Membership Cards 2Health News:Kashi Company Expands With New Island Vanilla(TM) Biscuit Cereal 2
... IMMULITE 2500 is a high-throughput immunoassay system ... the IMMULITE 2000 with the important addition ... ,allows assays to be designed for optimal ... ,This allows for critical assays such as ...
AxSYM Myoglobin is a Microparticle Enzyme Immunoassay (MEIA) for the quantitative determination of myoglobin in human serum or plasma on the AxSYM System....
IRMA kit for detection of the cardiac marker Myoglobin...
... is an immunometric ('sandwich') EIA ... Prolactin in human serum or ... is bound by 2 anti-Prolactin ... One antibody is attached to ...
Medicine Products: