Navigation Links
Pieris Progresses Proprietary Asthma Program: Validation of,Pulmonary Delivery of Anticalin-Based Protein Product Candidate

FREISING-WEIHENSTEPHAN, Germany, July 10, 2007 /PRNewswire/ -- Pieris AG, a bio-pharmaceutical company developing Anticalins(R), a novel class of targeted human protein therapeutics, today announced significant progress in validating novel, effective products for the potential treatment of asthma. In studies of its proprietary PRS-060 Anticalin(R) candidate, the Company reports that the protein can be effectively delivered to its target of action via the lungs.

PRS-060 has been selected by Pieris as being specific for a target implicated in a mechanism underlying asthma and other atopic diseases. The mode of action of the Anticalin(R) candidate is via modulation of the site of binding for multiple ligands.

"This important milestone demonstrates the exciting potential of Anticalin(R)-based products for the treatment of respiratory disease," said Dr Andreas Hohlbaum, Director of Science and Preclinical Development of Pieris. "In a simple preclinical biodistribution study quantitating PRS-060 Anticalin(R) delivered via a microspray device, we have already observed about 10-fold higher PRS-060 uptake than that typically obtained with monoclonal antibodies. Our findings have demonstrated the potential to deliver Anticalins(R) through alternative routes to injection and thereby exploit their intrinsic robustness and stability."

"This study confirms the ability of PRS-060 to be formulated in a way ideally suited to its application in asthma, namely in an inhaled preparation for home use," noted Evert Kueppers, Pieris Chief Executive Officer. "These findings continue to support the view that our Anticalin(R) platform, including its recent validation for dual targeting purposes, has enormous potential for application to human diseases that are currently inadequately treated."

The data will be presented for the first time on August 9th 2007 at IBC's Drug Discovery Technology Conference in Bost
'"/>




Page: 1 2

Related medicine technology :

1. Pieris Progresses Development of its Proprietary Biotherapeutics Platform: Successful Demonstration of Dual Targeting With Duocalin(R) Technology
2. Pieris Demonstrates Potent Anti-Tumor Activity of a VEGF-Specific Anticalin in Preclinical Studies
3. Neurogen Announces Positive Results for Proprietary Insomnia Drug in Two Chronic Insomnia Clinical Trials
4. Modigene Announces Successful Completion of Pharmacokinetic & Pharmacodynamic Pre-Clinical Experiments for Proprietary Long-Acting Human Growth Hormone, Long-acting Interferon Beta and Long-acting Erythropoietin
5. Neurogen Proprietary Insomnia Compound Data for Two Studies Presented at Associated Professional Sleep Societies Annual Meeting
6. Neurogen Proprietary Insomnia Compound Data Presented at Associated Professional Sleep Societies Annual Meeting
7. Neurogen Proprietary Insomnia Compound Data Presented at American Psychiatric Association Annual Meeting
8. Cytogen Reports Publication Validating the Utility of its Proprietary ProChart Database
9. Seattle Genetics Highlights Data on its Proprietary Antibody-Drug Conjugate Technology at AACR
10. Helix BioMedix to Discuss Potential of Its Proprietary Peptides at the BIO International Convention
11. Integrated Biopharmas Proprietary Vaccine Technology Achieves Strong Positive Results
Post Your Comments:
(Date:3/31/2015)... PARK, N.C. , March 31, 2015  Dr. ... will be attending the World Orphan Drug Congress in April ... regulatory approval process and orphan drugs below: ... (DTAB) has recommended to the Ministry of Health that if ... country, marketing authorization can be obtained in India ...
(Date:3/31/2015)...  On May 2, 2015 global experts on ... Santa Monica, CA at the 5th ... Pleural Mesothelioma (MPM), a rare form of cancer ... affects the lining of the chest– the pleura. ... Pacific Mesothelioma Center (PMC). ...
(Date:3/31/2015)... BC , March 31, 2015 /CNW/ - T-Bird Pharma ... focused on developing premium quality medical marijuana products and ... Marihuana for Medical Purposes Regulations ( Canada ... received notice from The Corporation of the District of ... approval of the Company,s premises which now allows for ...
Breaking Medicine Technology:Max Neeman to Discuss India's Orphan Drug Regulations at WOD 2015 2Cutting-Edge Research to Be Presented at 5th Annual International Symposium on Lung-Sparing Therapies for Malignant Pleural Mesothelioma in Santa Monica 2Cutting-Edge Research to Be Presented at 5th Annual International Symposium on Lung-Sparing Therapies for Malignant Pleural Mesothelioma in Santa Monica 3Cutting-Edge Research to Be Presented at 5th Annual International Symposium on Lung-Sparing Therapies for Malignant Pleural Mesothelioma in Santa Monica 4T-Bird Pharma Inc. Announces Final Municipal Rezoning Approval 2T-Bird Pharma Inc. Announces Final Municipal Rezoning Approval 3
... Bionovo, Inc.,(Nasdaq: BNVI ) announced today that its ... Phase 2 clinical testing after the,successful completion of a ... clinical trial was conducted to identify the maximum,tolerated dose ... of the,company,s novel, oral, anticancer treatment. A total of ...
... MedImmune today announced,that it has initiated a Phase ... healthy children one month to 12 months of age ... is,the most common respiratory infection in infants and can ... is a serious respiratory disease that can have significant ...
Cached Medicine Technology:Bionovo Advances BZL101 to Phase 2 Clinical Trials After Positive Phase 1 Results for Metastatic Breast Cancer 2Bionovo Advances BZL101 to Phase 2 Clinical Trials After Positive Phase 1 Results for Metastatic Breast Cancer 3Bionovo Advances BZL101 to Phase 2 Clinical Trials After Positive Phase 1 Results for Metastatic Breast Cancer 4MedImmune Advances Pediatric Disease Prevention Program With Start of Phase 1/2a Clinical Trial for Respiratory Syncytial Virus Vaccine 2
(Date:3/31/2015)... (PRWEB) March 31, 2015 The American ... events. The schedule for April will include interesting workshops, ... New Student Orientation, 9-11 a.m. April 6, ACTCM welcomes ... Room D at the Pioneer Square Campus located at ... Aid, 12:30-1:30 p.m. April 14, Students will be updated ...
(Date:3/31/2015)... Many people, including the ones with ... and cycling are only for able-bodied participants. , ... Institute aims to change that thinking. , The ... an Adaptive Sports Expo on Saturday, April 11 (10 ... in Hollywood. , The event will showcase a ...
(Date:3/31/2015)... (PRWEB) March 31, 2015 On March 26, ... Go Down the Silicone Slope?” provides a look into the ... filler , and laser treatments . The article suggests ... reality TV stars such as Kim Kardashian and Kylie Jenner ... media are increasingly seen as significant influences on the self-esteem ...
(Date:3/31/2015)... NJ (PRWEB) March 31, 2015 Dr. Russell ... for Advanced Reconstruction. He was recently quoted in an ... caused by lymphatic issues, causing fluid retention and tissue swelling. ... procedure to relieve and / or improve lymphedema symptoms. ... improve or alleviate the symptoms of lymphedema. The goal ...
(Date:3/31/2015)... March 31, 2015 Beckman Coulter is sponsoring ... USP 787: “Subvisible Particulate Matter in Therapeutic Protein Injections”,” an ... new demands in counting particles in liquids, with a focus ... webinar is free to attend and will be broadcast live ... posted a new test for protein-based materials, known as ...
Breaking Medicine News(10 mins):Health News:ACTCM Announces April Event Schedule 2Health News:Memorial Healthcare System's Adaptive Sports Expo Encourages Physically Challenged To Go Beyond Perceived Limitations 2Health News:Cosmetic Surgery: Does Social Media Pressure Young Girls to Get Botox and Fillers? 2Health News:The Physicians at Plastic Surgery Center Each Have Something to Celebrate This March 2Health News:The Physicians at Plastic Surgery Center Each Have Something to Celebrate This March 3Health News:The Physicians at Plastic Surgery Center Each Have Something to Celebrate This March 4Health News:Beckman Coulter Webinar Series Presents Insight into New Demands in Counting Particles in Liquids 2Health News:Beckman Coulter Webinar Series Presents Insight into New Demands in Counting Particles in Liquids 3
... ban on junk food in school canteens following a report ... its report// has shown concern about the increasing number of ... out by DDRC in 38 schools showed that one in ... food rampant in the school canteens contributed towards this cause. ...
... the source or inspiration of most new drugs created in the ... work in the natural// products branch of the National Cancer ... all new drugs approved from January 1981 through June 2006 for ... wide range of conditions. ,Only thirty percent of the ...
... the high during weekends. This is attributed to the quality ... patients. This study was conducted by William J. Kostis and ... New Jersey in New Brunswick. ,Kostis ... between the years 1987 and 2002. These were patients suffering ...
... Former Chhattisgarh's chief minister Ajit Jogi was hospitalized here ... arrested in connection// with the murder of Nationalist Congress ... was brought to Raipur at 4.10 a.m. Monday and ... chest pain," Jogi's family sources told IANS. ...
... A new study that was published in Britain indicates that the ... still more than the desired// level. Health experts opine that cardiac ... salt intake. ,According to the report, there is a ... last measured in 2001. Men have cut down their salt intake ...
... hormone that is important in the control of blood pressure ... way to prevent or treat the deadly cancer, according to ... scientists said that in mice treated with the hormone, angiotensin-(1-7), ... not receive the treatment, the tumor size more than doubled. ...
Cached Medicine News:Health News:Drug for Blood Pressure also Treats Lung Cancer 2
... valve is enclosed in a ... the valve from being accidentally ... or reclining positions. The valve ... free ensuring uninterrupted flow and ...
Intermittent catheter - Ready-to-Use Sterile, Enclosed System...
... The VerifyNow (Ultegra) System is ... which measures platelet induced aggregation as ... system consists of an instrument, a ... assay device contains reagents based on ...
... The Model 700 Whole Blood/Optical Lumi-Aggregometer available ... This new Aggregometer measures platelet function on ... blood or optical density in plasma with ... method. The Model 700 Aggregometer also has ...
Medicine Products: