Navigation Links
Pieris Progresses Proprietary Asthma Program: Validation of,Pulmonary Delivery of Anticalin-Based Protein Product Candidate

FREISING-WEIHENSTEPHAN, Germany, July 10, 2007 /PRNewswire/ -- Pieris AG, a bio-pharmaceutical company developing Anticalins(R), a novel class of targeted human protein therapeutics, today announced significant progress in validating novel, effective products for the potential treatment of asthma. In studies of its proprietary PRS-060 Anticalin(R) candidate, the Company reports that the protein can be effectively delivered to its target of action via the lungs.

PRS-060 has been selected by Pieris as being specific for a target implicated in a mechanism underlying asthma and other atopic diseases. The mode of action of the Anticalin(R) candidate is via modulation of the site of binding for multiple ligands.

"This important milestone demonstrates the exciting potential of Anticalin(R)-based products for the treatment of respiratory disease," said Dr Andreas Hohlbaum, Director of Science and Preclinical Development of Pieris. "In a simple preclinical biodistribution study quantitating PRS-060 Anticalin(R) delivered via a microspray device, we have already observed about 10-fold higher PRS-060 uptake than that typically obtained with monoclonal antibodies. Our findings have demonstrated the potential to deliver Anticalins(R) through alternative routes to injection and thereby exploit their intrinsic robustness and stability."

"This study confirms the ability of PRS-060 to be formulated in a way ideally suited to its application in asthma, namely in an inhaled preparation for home use," noted Evert Kueppers, Pieris Chief Executive Officer. "These findings continue to support the view that our Anticalin(R) platform, including its recent validation for dual targeting purposes, has enormous potential for application to human diseases that are currently inadequately treated."

The data will be presented for the first time on August 9th 2007 at IBC's Drug Discovery Technology Conference in Bost
'"/>




Page: 1 2

Related medicine technology :

1. Pieris Progresses Development of its Proprietary Biotherapeutics Platform: Successful Demonstration of Dual Targeting With Duocalin(R) Technology
2. Pieris Demonstrates Potent Anti-Tumor Activity of a VEGF-Specific Anticalin in Preclinical Studies
3. Neurogen Announces Positive Results for Proprietary Insomnia Drug in Two Chronic Insomnia Clinical Trials
4. Modigene Announces Successful Completion of Pharmacokinetic & Pharmacodynamic Pre-Clinical Experiments for Proprietary Long-Acting Human Growth Hormone, Long-acting Interferon Beta and Long-acting Erythropoietin
5. Neurogen Proprietary Insomnia Compound Data for Two Studies Presented at Associated Professional Sleep Societies Annual Meeting
6. Neurogen Proprietary Insomnia Compound Data Presented at Associated Professional Sleep Societies Annual Meeting
7. Neurogen Proprietary Insomnia Compound Data Presented at American Psychiatric Association Annual Meeting
8. Cytogen Reports Publication Validating the Utility of its Proprietary ProChart Database
9. Seattle Genetics Highlights Data on its Proprietary Antibody-Drug Conjugate Technology at AACR
10. Helix BioMedix to Discuss Potential of Its Proprietary Peptides at the BIO International Convention
11. Integrated Biopharmas Proprietary Vaccine Technology Achieves Strong Positive Results
Post Your Comments:
(Date:5/23/2013)... May 23, 2013  A recently published clinical study ... Houston, Texas , demonstrates that 3D mammography (breast ... detection. The study, "Implementation of Breast ... was led by Stephen L. Rose ... the American Journal of Roentgenology (AJR). The ...
(Date:5/23/2013)... , May 23, 2013  The need to ... treatment continuum was highlighted prominently at the 108 ... Association (AUA), in San Diego.  According to SonaCare ... focused ultrasound (HIFU) technology, the need for image-guided ... for urologists to consider minimally invasive ablative treatments, ...
(Date:5/23/2013)... , May 23, 2013  Hologic, Inc. (Hologic ... a leading developer, manufacturer and supplier of premium ... an emphasis on serving the healthcare needs of ... study in a U.S. clinical practice comparing breast ... tomosynthesis) with conventional 2D mammography alone showed a ...
Breaking Medicine Technology:First Large-Scale U.S. Study Validates the Benefits of 3D Mammography (Breast Tomosynthesis) Exams 2First Large-Scale U.S. Study Validates the Benefits of 3D Mammography (Breast Tomosynthesis) Exams 3Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 2Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 3Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 4Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 5Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 6First Large-Scale Population-Based Study in the U.S. Shows Hologic's 3D Mammography (Breast Tomosynthesis) Significantly Reduces Recall Rates While Simultaneously Improving Cancer Detection 2First Large-Scale Population-Based Study in the U.S. Shows Hologic's 3D Mammography (Breast Tomosynthesis) Significantly Reduces Recall Rates While Simultaneously Improving Cancer Detection 3First Large-Scale Population-Based Study in the U.S. Shows Hologic's 3D Mammography (Breast Tomosynthesis) Significantly Reduces Recall Rates While Simultaneously Improving Cancer Detection 4
...  UCB today announced new findings for Vimpat® (lacosamide) ... effects of the antiepileptic drug (AED) as an ...  The data demonstrate reduced seizure severity and improvements ...  These and other Vimpat® data were presented at ...
... 5, 2011 ForteBio®, Inc., a leading supplier of ... pharmaceutical products, today announced the launch of BLItz™, a ... the first time – to conduct label-free analyses of ... their lab bench. The new platform was unveiled today ...
Cached Medicine Technology:Long-term Use of Antiepileptic Drug Vimpat® (Lacosamide) C-V Reduced Seizure Frequency and Severity and Improved Health-related Quality of Life Measures 2Long-term Use of Antiepileptic Drug Vimpat® (Lacosamide) C-V Reduced Seizure Frequency and Severity and Improved Health-related Quality of Life Measures 3Long-term Use of Antiepileptic Drug Vimpat® (Lacosamide) C-V Reduced Seizure Frequency and Severity and Improved Health-related Quality of Life Measures 4Long-term Use of Antiepileptic Drug Vimpat® (Lacosamide) C-V Reduced Seizure Frequency and Severity and Improved Health-related Quality of Life Measures 5Long-term Use of Antiepileptic Drug Vimpat® (Lacosamide) C-V Reduced Seizure Frequency and Severity and Improved Health-related Quality of Life Measures 6Long-term Use of Antiepileptic Drug Vimpat® (Lacosamide) C-V Reduced Seizure Frequency and Severity and Improved Health-related Quality of Life Measures 7Long-term Use of Antiepileptic Drug Vimpat® (Lacosamide) C-V Reduced Seizure Frequency and Severity and Improved Health-related Quality of Life Measures 8Long-term Use of Antiepileptic Drug Vimpat® (Lacosamide) C-V Reduced Seizure Frequency and Severity and Improved Health-related Quality of Life Measures 9Long-term Use of Antiepileptic Drug Vimpat® (Lacosamide) C-V Reduced Seizure Frequency and Severity and Improved Health-related Quality of Life Measures 10ForteBio Introduces BLItz™, a Revolutionary, Micro-volume Label-free Analysis Platform for Personal Assays 2ForteBio Introduces BLItz™, a Revolutionary, Micro-volume Label-free Analysis Platform for Personal Assays 3
(Date:5/26/2013)... May 26, 2013 In the five years ... China has been growing at an average annualized rate ... due to rises in poultry prices as well as output ... people's diets as a healthier alternative to other meats. Additionally, ... China, much lower than the world average. And although pork ...
(Date:5/25/2013)... According to an article in the June 2013 issue ... million Americans tan indoors each year and an unknown number ... health risks. New research suggests that UV rays may ... brains of some tanners (Go to goo.gl/hdwnz). , “There ... say that I fully support this contention from a scientific ...
(Date:5/25/2013)... 2013 An experienced Chandler dentist has ... with JD Media Surge, LLC. , http://www.ChandlerDentalExcellence.com/Teeth-Whitening.php ... and, depending on the treatment, can be performed in ... the best method will be chosen for the individual ... visit. A special peroxide-based whitening gel is used along ...
(Date:5/25/2013)... (HealthDay News) -- Many viruses and parasites that affect ... -- a bacteria-borne illness than can result in liver ... parks, according to a veterinarian. These germs ... the air, said Dr. Susan Nelson, a clinical associate ... of these serious diseases can be fatal, even with ...
(Date:5/25/2013)... (PRWEB) May 25, 2013 Providing patients with ... Diet Doc team of weight management professionals. But, aside from ... and effectively, Diet Doc’s hCG diets also provide ... abuse during childhood like bullying, more control over their lives ... of dealing with the underlying factors of weight gain derived ...
Breaking Medicine News(10 mins):Health News:Poultry Farming Industry in China Industry Research Report – Now Available from IBISWorld 2Health News:Poultry Farming Industry in China Industry Research Report – Now Available from IBISWorld 3Health News:Sun Damage – Are UV Rays Addictive? 2Health News:Chandler Dentist Launches Teeth Whitening Service Page on Website in Partnership with JD Media Surge, LLC 2Health News:Hidden Dangers Dog Dog Parks 2Health News:hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Announces hCG Diet Plans for Those Suffering from Abuse-Related Weight Gain 2Health News:hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Announces hCG Diet Plans for Those Suffering from Abuse-Related Weight Gain 3
... By Alan Mozes HealthDay Reporter , WEDNESDAY, ... suicide risk appears to be significantly higher among people ... The latest observation seems to confirm the findings of ... fully explained relationship between higher than average suicide rates ...
... hemorrhagic fever in humans, has no known cure or vaccine. ... scientists has uncovered a family of small molecules which appear ... inhibit its entry into human cells. The results are ... and are now online. Previous studies have shown ...
... Inserm research team in Toulouse, led by Dr Stein ... working with the "Modelling tissue and nociceptive stress" Host ... illusions described by many patients under regional anaesthetic. In ... Anesthesiology , the researchers demonstrated that anaesthetising an arm ...
... News) -- Many U.S. transplant surgeons unnecessarily shun organs ... safeguards that would protect and inform transplant recipients, a ... in the nation "overreacted" to a 2007 case in ... organs from a single donor unknowingly infected with HIV, ...
... January 20, 2011) Cancer scientists led by ... and collaborators at St Jude Children,s Research Hospital (Memphis) ... cells that carry them are organized in a more ... published today in Nature (DOI:10.1038/nature09733), challenge the ...
... By Charnicia Huggins HealthDay Reporter , ... tongue piercing as a form of self-expression, know that ... metal or plastic makes a difference when it comes ... collect more bacteria than plastic studs, potentially increasing the ...
Cached Medicine News:Health News:High Altitude Linked to Higher Suicide Risk -- Again 2Health News:High Altitude Linked to Higher Suicide Risk -- Again 3Health News:High Altitude Linked to Higher Suicide Risk -- Again 4Health News:Small molecules may prevent ebola infection 2Health News:How does anesthesia disturb self-perception? 2Health News:Cancer scientists discover genetic diversity in leukemic propagating cells 2Health News:Cancer scientists discover genetic diversity in leukemic propagating cells 3Health News:Metal Tongue Piercings Linked to Raised Infection Risks 2Health News:Metal Tongue Piercings Linked to Raised Infection Risks 3
This double-up gel dryer system, 200-240 V, includes 2 Model 583 gel dryers, HydroTech™ vacuum pump, and double-up rack....
... The GelAir™ drying system utilizes a hot ... Gels are dried on a clear cellophane support ... to provide a smooth, flat assembly surface for ... four drying frames at once. This 115 V, ...
The GelAir™ dryer is a component of the GelAir drying system. Supplied as a 115 V, 60 Hz gel drying oven....
... The 1000-90 is the most versatile power ... up to 1000 volts or 1250 milliamps ... competition. No other 1000 volt power supply ... for large protein gels or small focusing ...
Medicine Products: