Navigation Links
Pieris Progresses Proprietary Asthma Program: Validation of,Pulmonary Delivery of Anticalin-Based Protein Product Candidate

FREISING-WEIHENSTEPHAN, Germany, July 10, 2007 /PRNewswire/ -- Pieris AG, a bio-pharmaceutical company developing Anticalins(R), a novel class of targeted human protein therapeutics, today announced significant progress in validating novel, effective products for the potential treatment of asthma. In studies of its proprietary PRS-060 Anticalin(R) candidate, the Company reports that the protein can be effectively delivered to its target of action via the lungs.

PRS-060 has been selected by Pieris as being specific for a target implicated in a mechanism underlying asthma and other atopic diseases. The mode of action of the Anticalin(R) candidate is via modulation of the site of binding for multiple ligands.

"This important milestone demonstrates the exciting potential of Anticalin(R)-based products for the treatment of respiratory disease," said Dr Andreas Hohlbaum, Director of Science and Preclinical Development of Pieris. "In a simple preclinical biodistribution study quantitating PRS-060 Anticalin(R) delivered via a microspray device, we have already observed about 10-fold higher PRS-060 uptake than that typically obtained with monoclonal antibodies. Our findings have demonstrated the potential to deliver Anticalins(R) through alternative routes to injection and thereby exploit their intrinsic robustness and stability."

"This study confirms the ability of PRS-060 to be formulated in a way ideally suited to its application in asthma, namely in an inhaled preparation for home use," noted Evert Kueppers, Pieris Chief Executive Officer. "These findings continue to support the view that our Anticalin(R) platform, including its recent validation for dual targeting purposes, has enormous potential for application to human diseases that are currently inadequately treated."

The data will be presented for the first time on August 9th 2007 at IBC's Drug Discovery Technology Conference in Bost on, MA, USA.

Pieris is now actively seeking development partners for this program with specialization in product development for respiratory diseases, including asthma.

    Further information is available at http://www.pieris-ag.com

    Anticalin(R) and Duocalin(R) are registered trademarks of Pieris AG.


    For further information, please contact:


    Pieris AG

    Dr Birgit Zech, Senior Manager Business Development

    Phone +49-(0)-8161-1411-400



CONTACT: For further information, please contact: Pieris AG, Dr BirgitZech, Senior Manager Business Development, Phone +49-(0)-8161-1411-400

Terms and conditions of use apply
Copyright © 2007 PR Newswire Association LLC. All rights reserved.
A United Business Media Company


'"/>




Related medicine technology :

1. Pieris Progresses Development of its Proprietary Biotherapeutics Platform: Successful Demonstration of Dual Targeting With Duocalin(R) Technology
2. Pieris Demonstrates Potent Anti-Tumor Activity of a VEGF-Specific Anticalin in Preclinical Studies
3. Neurogen Announces Positive Results for Proprietary Insomnia Drug in Two Chronic Insomnia Clinical Trials
4. Modigene Announces Successful Completion of Pharmacokinetic & Pharmacodynamic Pre-Clinical Experiments for Proprietary Long-Acting Human Growth Hormone, Long-acting Interferon Beta and Long-acting Erythropoietin
5. Neurogen Proprietary Insomnia Compound Data for Two Studies Presented at Associated Professional Sleep Societies Annual Meeting
6. Neurogen Proprietary Insomnia Compound Data Presented at Associated Professional Sleep Societies Annual Meeting
7. Neurogen Proprietary Insomnia Compound Data Presented at American Psychiatric Association Annual Meeting
8. Cytogen Reports Publication Validating the Utility of its Proprietary ProChart Database
9. Seattle Genetics Highlights Data on its Proprietary Antibody-Drug Conjugate Technology at AACR
10. Helix BioMedix to Discuss Potential of Its Proprietary Peptides at the BIO International Convention
11. Integrated Biopharmas Proprietary Vaccine Technology Achieves Strong Positive Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/6/2017)... , Sept. 6, 2017  Medical ... knowledge and skills while treating their patients. ... hands-on experience without involving patients. Simulation provides ... Clinicians can carry out procedures, refine techniques ... risk. Integration of new technology, such as ...
(Date:9/5/2017)... -- Xyntek Inc. has announced another milestone in their continued growth and success of ... growing demands of customer engagements regionally.  ... Midwest office is located at 318 West Adams Street, Suite 1528, Chicago, IL ... Xyntek's recently opened Midwest ... In ...
(Date:9/1/2017)... , Sept. 1, 2017  Explorers Like Us ( ... America,s greatest aural experiences — and deliver these experiences as ... to help people feel and heal better. ... While nothing beats a walk, ... refresh your mind, Life Environments™ is the next best thing ...
Breaking Medicine Technology:
(Date:9/25/2017)... ... September 25, 2017 , ... 12th Annual ... FDAnews**, Nov. 1-3, 2017 – Bethesda, MD, http://www.fdanews.com/fdainspectionssummit , Nine times ... then, on the tenth inspection it failed. , What went wrong? , Come ...
(Date:9/24/2017)... ... 25, 2017 , ... Bhowanie Benimadhu’s new book “ Our Creative World: Our ... and seeks answers in both Eastern and Western religious traditions and spirituality such as ... the mind of humankind for the past thousands of years and still are,” Benimadhu ...
(Date:9/24/2017)... ... ... Throughout the United States and the world, clinicians take a simple but powerful ... work to give the best care possible to patients and communities, while seeking newer, ... threatening to tie our hands in carrying out that oath. The Graham-Cassidy legislation to ...
(Date:9/24/2017)... ... September 24, 2017 , ... “The Messiah 8 with the ... texts to firsthand experiences. “The Messiah 8 with the 3rd Anti Christ” is the ... I’ve tried to look at all the angles of life,” Velazquez states, “I always ...
(Date:9/24/2017)... ... 24, 2017 , ... “The Gospel Truth Of The Bible: The Other Sheep”: the ceremonial laws ... Bible: The Other Sheep” is the creation of published author, Maurice Caines. Maurice Caines ... He has been a member of the Seventh-day Adventist Church for many years. ...
Breaking Medicine News(10 mins):