Navigation Links
Pieris Demonstrates Potent Anti-Tumor Activity of a VEGF-Specific,Anticalin in Preclinical Studies

ris AG

Pieris is a biopharmaceutical company engaged in the discovery and development of Anticalins(R), human non-antibody binding proteins, for the diagnosis and treatment of life-threatening human disorders. Exploiting extensive know-how in protein engineering as part of a broad intellectual property portfolio, the Company applies a balanced risk business model to the development of its Anticalin(R) candidates. To date, Pieris has reached all development milestones on time under the agreements with its industry partners. Recognizing the enormous market potential of protein-based drugs, Pieris is committed to becoming an integrated drug discovery and development company.

About the Anticalin(R) technology

Anticalins(R) are derived from the lipocalin scaffold, originally developed by Prof. Dr. Arne Skerra, a leading expert in the field and Head of the Department of Biological Chemistry at the Technical University of Munich, Germany. As engineered human proteins, Anticalins(R) have prescribed binding properties and have fundamental similarities with fully human antibodies e.g. picomolar potency and expected low immunogenicity. Anticalins(R) have several additional advantages over conventional antibodies due to their small size (20 kDa), robust tertiary structure and straight composition that confer high solubility, predictable stability and bacterial manufacturability. Fast pharmaco-kinetics and favorable tissue penetration of Anticalins(R) can be balanced through adjustable modulation of serum half-life and valency by established methodologies.

By developing Anticalin(R) based products, Pieris and its collaborators are not only able to develop superior biotherapeutics, but they also have the ability to overcome the encumbering patent landscape as currently present for developing conventional antibodies.

About VEGF and PRS-050

Angiogenesis - the development of new blood vessels from pre-existing vasculature - plays an importan
'"/>




Page: 1 2 3

Related medicine technology :

1. Pieris Progresses Proprietary Asthma Program: Validation of Pulmonary Delivery of Anticalin-Based Protein Product Candidate
2. Pieris Progresses Development of its Proprietary Biotherapeutics Platform: Successful Demonstration of Dual Targeting With Duocalin(R) Technology
3. The International Myeloma Foundation Says Data Reported at a Global Medical Meeting in Greece Demonstrates Improved Survival for a Wide Range of Myeloma Patients
4. Publication on Pixantrone Preclinical Studies Demonstrates Reduced Cardiotoxicity Compared to Equiactive Doses of Doxorubicin and Mitoxantrone
5. New Research Demonstrates Broad Efficacy of Azixa (MPC-6827) Against Multiple Tumor Types and in Drug Resistant Cell Lines
6. Algeta Demonstrates Targeted Cancer-killing Potential of Novel Alpha Particle Linked Antibodies in Leading Medical Journal Blood
7. Gerons Telomerase Inhibitor Cancer Drug Demonstrates Good Pharmacokinetics and Tolerability in Phase I/II Trial
8. Frova Phase III Study Data Demonstrates That Short-Term Prevention Treatment Reduces Frequency and Severity of Menstrual Migraine
9. Mymetics HIV Vaccine Demonstrates First-Ever Production of Neutralizing IgA Antibodies in Non-Human Primate Model
10. Newly Published Data Demonstrates Superiority of Cipralex Over Duloxetine for Acute Treatment of Depression
11. Introgens Advexin Demonstrates Clinical Benefit in Inherited Cancer
Post Your Comments:
(Date:7/28/2014)... July 28, 2014 KaloBios Pharmaceuticals, Inc. (Nasdaq: ... the status of the KB001-A development program, including an ... KB001-A Collaboration Update KaloBios ... Pasteur to regain all rights to KaloBios, KB001-A program. ... into in 2010 has been terminated. Under that collaboration ...
(Date:7/28/2014)... RESTON, Va. , July 28, 2014 /PRNewswire/ ... management services, announced the Company has been awarded ... Medical Support Command (NEMSCOM) and its Deployable Medical ... to enable medical personnel to provide world-class healthcare ... any operating environment across the globe. The five ...
(Date:7/28/2014)... 28, 2014  Array BioPharma Inc. (Nasdaq:   ... fourth quarter and full year of fiscal ... discuss those results on Tuesday, August 12, ... Michael Carruthers , Chief Financial Officer ... 12, 2014Time:9:00 a.m. Eastern TimeToll-Free:(800) 708-4540Toll:(847) 619-6397Pass ...
Breaking Medicine Technology:KaloBios Provides Update on KB001-A Partnership and Clinical Status 2KaloBios Provides Update on KB001-A Partnership and Clinical Status 3KaloBios Provides Update on KB001-A Partnership and Clinical Status 4KaloBios Provides Update on KB001-A Partnership and Clinical Status 5KaloBios Provides Update on KB001-A Partnership and Clinical Status 6Serco Awarded $22.7 Million Contract to Support Deployable Medical Systems 2
(Date:7/29/2014)... Oconto Falls, WI (PRWEB) July 29, 2014 ... their third development project, The Cottages at MeadowLands Memory ... the growing population of those suffering from memory loss ... W.M. Enterprises, Inc., has approved the development of Oconto ... memory care. Cara Peterson, GM of The Cottages Investment ...
(Date:7/29/2014)... 29, 2014 Tucson-based company Outski ... benefits package, or health and wellness program, called 401(play)™. ... providing an effective way for employees to use their ... the program, employees specify the amount of each paycheck ... An employer benefits from offering a 401(play)™ plan to ...
(Date:7/29/2014)... latest blog post at http://www.perwickstrom.com , entrepreneur, author, speaker ... ways to light the “fire” in employees. , “Employers are ... some it’s a losing battle,” commented Per Wickstrom . ... employees get to the next level; which not only helps ... Per Wickstrom, 6 ways to light the “fire” in employees ...
(Date:7/29/2014)... 29, 2014 Launched in 2012 by ... surpassed 20,000 hangovers earlier this year at its Vegas ... expansion and the publication of research data related to ... practice. , The only licensed medical practice dedicated to ... launched in 2012 and treated thousands of patients within ...
(Date:7/29/2014)... July 29, 2014 The Marietta cosmetic ... teeth whitening for high school and college students ... The teeth whitening is a safe, professional strength system, ... better confidence for students at these important stages in life. ... but have never had their teeth whitened. "After braces, ...
Breaking Medicine News(10 mins):Health News:The Cottages Investment Group Announces Third Development Project, The Cottages at MeadowLands Memory Care, Oconto Falls 2Health News:The Cottages Investment Group Announces Third Development Project, The Cottages at MeadowLands Memory Care, Oconto Falls 3Health News:The Cottages Investment Group Announces Third Development Project, The Cottages at MeadowLands Memory Care, Oconto Falls 4Health News:Outski launches 401(play)™ Plan to Employers as Part of an Employee Benefit / Health and Wellness Program 2Health News:Per Wickstrom’s Latest Blog Post Lists 6 Ways to Light the “Fire” in Employees 2Health News:Hangover Heaven Surpasses 20,000 Hangovers 2Health News:Hangover Heaven Surpasses 20,000 Hangovers 3Health News:Back to School Teeth Whitening Extravaganza For High School Students and Collegiates During August 2014 2Health News:Back to School Teeth Whitening Extravaganza For High School Students and Collegiates During August 2014 3
... of patent pending technologies, WELLINGTON, Fla., March ... QGP.WSB) (http://www.QuantumMD.com ) announced today that,the Board ... President and,Chief Executive Officer; have reached an agreement ... things, extend his term of employment,with the Company. ...
... to herbicides and insecticides , , FRIDAY, March 28 (HealthDay ... to pesticides in a new study comparing people with ... The study, published online in the open-access journal ... use of herbicides and insecticides, such as organochlorides and ...
... continuing economic,woes, applying quality initiatives to customer service ... great service to help establish a,premium for product ... new product development. "There is a greater need ... "Using Quality to Improve the Customer Experience," the ...
... A new survey shows that more than,two-thirds of consumers ... recent approval of the Food and Drug Administration., ... percent of,respondents said they were unsure about the safety ... Many respondents referred to,Dolly, the first cloned sheep, and ...
... YORK, March 27 Ten years ago, ... dysfunction launched a revolution in the way ... this report from Pfizer (NYSE: PFE ... can access video, audio, text, graphics and,photos ...
... testing likely contributed to increase , , THURSDAY, March ... United States have increased 123 percent in a decade, ... middle-aged patients, according to new findings. , The increases ... for which data are available. Death rates peaked in ...
Cached Medicine News:Health News:The Quantum Group Extends CEO's Employment Agreement 2Health News:The Quantum Group Extends CEO's Employment Agreement 3Health News:Family Study Associates Pesticide Use With Parkinson's Risk 2Health News:Superior Customer Service Imperative During Economic Downturn 2Health News:Sharp Rise in U.S. Hepatitis C-Related Deaths 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: