Navigation Links
Phase III Trial Results Show Superiority of Rivaroxaban over,Enoxaparin for the Prevention of Venous Thromboembolism in Patients,Undergoing Knee Replacement Surgery

eeding rates were 0.6% and 0.5%, and any bleeding rates were 4.9% and 4.8%, respectively. The RECORD3 trial demonstrated superior efficacy of rivaroxaban versus enoxaparin, with similarly low bleeding rates, in patients undergoing TKR.

Head of Global Development Dr. Kemal Malik, a member of Bayer HealthCare Executive Committee and management board member of Bayer Schering Pharma, commented: "Based on the data we have generated, rivaroxaban shows great promise that it could set a new standard of care in thromboembolic disease as a new benchmark for balancing safety and efficacy in anticoagulation. We hope that the clinical trials will continue to demonstrate the compelling efficacy and safety profile for rivaroxaban, while also demonstrating its utility in both the hospital and home settings without the need for routine monitoring."

The trade name of rivaroxaban is expected to be Xarelto®, pending health authority approval.

Additional Phase III results of the ongoing RECORD program are expected to be available during H2 2007.

Unmet Needs in Venous Thromboembolism (VTE) VTE is a type of thromboembolic disease that affects approximately 6.5 million people worldwide annually. Thromboembolic disease, which is caused by the obstruction of a blood vessel by a blood clot, is a leading cause of global mortality and a concern for many patient populations, including those with atrial fibrillation at risk for stroke; those at risk for acute myocardial infarction (heart attack); those undergoing orthopaedic surgery at risk for developing DVT and PE; and hospitalized, medically ill patients immobilized by cancer, congestive heart failure, acute respiratory disease, or other illnesses.

About Rivaroxaban (Xarelto®) Phase IIb data - presented at ISTH in 2005, and published in the Journal of Thrombosis and Haemostasis in 2005 and 2006, and the additional once-daily ODIXa HIP study published in Circulation in 2006 - indicate that rivaroxaban
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
2. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
3. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
4. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
5. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
6. Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis
7. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
8. NexMed Announces Completion of Patient Enrollment in Two Pivotal Phase 3 Studies for Anti-Fungal Product
9. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
10. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
11. TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment
Post Your Comments:
(Date:5/5/2015)... 5, 2015 Big Market Research presents a ... Europe , ( France , ... , UK) and Japan . Current scientific ... report provides the 5-year test volume and sales forecasts by country ... Anti-HBs, Anti-HAV, Hepatitis Delta, HBc Ag, HBe Ag, and ALT/SGPT tests ...
(Date:5/5/2015)... , May 5, 2015  Image Stream Medical, a ... agreement with MedAssets, one of the largest group purchasing ... United States.  Under terms of the three-year agreement, Image ... services will be made available to MedAssets members beginning ... partnership, Image Stream Medical CEO Eddie Mitchell ...
(Date:5/5/2015)... , May 05, 2015 Research and ... the addition of the "Clinical Laboratory,Molecular Diagnostics ... 2015 to 2019 - Asia Pacific Version" ... that just keeps on growing. Clinical laboratory testing ... in biotechnology, especially genomics. A range of dynamic ...
Breaking Medicine Technology:2015 Opportunities in the Global Hepatitis Diagnostic Testing Market: Big Market Research 22015 Opportunities in the Global Hepatitis Diagnostic Testing Market: Big Market Research 3Image Stream Medical Announces Agreement with MedAssets 2Asia Pacific Clinical Laboratory, Molecular Diagnostics and Genomic Testing Services Market Report 2015-2019 2
... 2011 MedCath Corporation (Nasdaq: MDTH ) will ... 9, 2011 to announce results from its first fiscal quarter ... not to host a conference call to review its first ... Charlotte, N.C., is a healthcare provider focused on high acuity ...
... ThermoGenesis Corp. (Nasdaq: KOOL ), a leading ... store adult stem cells, and TotipotentSC, a U.S. company ... therapy and clinical research management, announced today they have ... Committee to proceed with a Phase Ib clinical trial ...
Cached Medicine Technology:ThermoGenesis Corp. and TotipotentSC Receive Approval for Phase Ib Clinical Trial of Res-Q™ 60 BMC for Treatment of Critical Limb Ischemia 2ThermoGenesis Corp. and TotipotentSC Receive Approval for Phase Ib Clinical Trial of Res-Q™ 60 BMC for Treatment of Critical Limb Ischemia 3ThermoGenesis Corp. and TotipotentSC Receive Approval for Phase Ib Clinical Trial of Res-Q™ 60 BMC for Treatment of Critical Limb Ischemia 4
(Date:5/5/2015)... Warner, NH (PRWEB) May 05, 2015 For ... created the HiTemp140 series of data loggers. This data ... body, housing the electronic components for optimum performance throughout exposure ... HiTemp140 data loggers are capable of storing up ... a typical battery life of one year or longer. All ...
(Date:5/5/2015)... May 05, 2015 Sheltering Arms held ... Walt “Clyde” Frazier and Cravath, Swaine & Moore LLP ... highest-need communities. The event was co-chaired by Vanguard sponsors ... “The Next Chapter” highlighted Sheltering Arms’ significant growth in ... unveiled in February 2015. Formerly Episcopal Social Services, Sheltering ...
(Date:5/5/2015)... Francisco, California (PRWEB) May 05, 2015 ... based in San Francisco, leads an international initiative to ... order to extend the human lifespan. Scientists at ... inherent to women, from the initiation of her menstrual ... a possible mechanism for aging and, ultimately, extend the ...
(Date:5/5/2015)... Crawford Technologies announced today it has been awarded a ‘2015 ... the Business Marketing Association (BMA) for the redesign of Crawford ... to the CrawfordTech marketing team on Friday, May 1, at ... people in attendance. , “The launch of the new Crawford ... in focus for how our company communicates our value and ...
(Date:5/5/2015)... May 05, 2015 The PracticeMatch Career ... 5:00 to 8:00 pm at the Rochester Marriott, 1001 First ... and groups with career opportunities will be attending from across ... free hors d’oeuvres and raffle prize drawings. , Leslie Thompson, ... is an ideal location to hold a career fair. In ...
Breaking Medicine News(10 mins):Health News:MadgeTech High Temperature Data Logger Series Expands for Growing Demands 2Health News:MadgeTech High Temperature Data Logger Series Expands for Growing Demands 3Health News:MadgeTech High Temperature Data Logger Series Expands for Growing Demands 4Health News:MadgeTech High Temperature Data Logger Series Expands for Growing Demands 5Health News:MadgeTech High Temperature Data Logger Series Expands for Growing Demands 6Health News:Sheltering Arms Honors Walt "Clyde" Frazier and Cravath, Swaine & Moore LLP at Annual Gala 2Health News:Igantia Announces Digital Initiative to Decode Longevity 2Health News:Crawford Technologies Awarded BMA’s ‘2015 Gold Key Award’ for Innovative Website Redesign 2Health News:Crawford Technologies Awarded BMA’s ‘2015 Gold Key Award’ for Innovative Website Redesign 3Health News:PracticeMatch to Host Physician Career Fair at the Rochester Marriott on May 12, 2015 2Health News:PracticeMatch to Host Physician Career Fair at the Rochester Marriott on May 12, 2015 3
... is a,statement by Christine James-Brown, President and CEO, CWLA:, ... authority and opportunity,to delay the Medicaid Rehabilitative Services and ... controversial rules by including a,moratorium on them in the ... made a loud and clear statement that it is ...
... Hospital Opening Schedule; Eases Ongoing IT Development ... ... 1 TIBCO Software Inc.,(Nasdaq: TIBX ) today announced that ... its real-time integration,infrastructure. The project at Servicio Riojano de Salud (SERIS) ...
... Inc., a Johnson &,Johnson company, today announced it ... Partners to acquire the Professional,Wound Care business. ETHICON ... divestiture of the Professional Wound Care business, and ... the offer has decided to grant,exclusivity to One ...
... Friends self-help support organization for families going through ... a child is hosting its 31st national conference ... parents, siblings, and grandparents, as well as professionals ... conference. Highlights include well-known speakers, more than 100 ...
... Security and Liability Insurers Committed ... 1 The Health Information Trust Alliance,(HITRUST) today ... the first-ever,Common Security Framework (CSF) by January 2009, ... organizations, professional services firms,information security specialists, liability insurers ...
... AMDL, Inc. (Amex:,ADL), a leading vertically integrated ... operations in the U.S. and,China, announced today ... signed between,AMDL,s wholly-owned subsidiary Jade Pharmaceutical Inc. ... SZP is a,privately-held China-based pharmaceutical distribution company ...
Cached Medicine News:Health News:Statement by Christine James-Brown, President and CEO, Child Welfare League of America (CWLA) Re: Moratorium on Medicaid Regulations 2Health News:Rioja Hospital Uses TIBCO Software to Improve Customer Care and Streamline Operations 2Health News:ETHICON Receives Offer from One Equity Partners to Purchase Professional Wound Care Business 2Health News:ETHICON Receives Offer from One Equity Partners to Purchase Professional Wound Care Business 3Health News:ETHICON Receives Offer from One Equity Partners to Purchase Professional Wound Care Business 4Health News:Families Mourning Children Travel to Nashville for July Compassionate Friends National Conference 2Health News:HITRUST Confirms Release Date for First-Ever Common Security Framework for Electronic Health Information 2Health News:HITRUST Confirms Release Date for First-Ever Common Security Framework for Electronic Health Information 3Health News:HITRUST Confirms Release Date for First-Ever Common Security Framework for Electronic Health Information 4Health News:HITRUST Confirms Release Date for First-Ever Common Security Framework for Electronic Health Information 5Health News:AMDL Signs Letter of Intent to Purchase China-Based Pharmaceutical Distribution Company 2Health News:AMDL Signs Letter of Intent to Purchase China-Based Pharmaceutical Distribution Company 3
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
PremierEdge™ Tunnel Knives....
The Astigmatome makes precise and accurate cuts for astigmatism correction simply and safely....
Medicine Products: