Navigation Links
Pharmion's Amrubicin Shows Encouraging Results Compared to Standard,of Care in Second Line Treatment of Small Cell Lung Cancer

Interim Analysis of Phase 2 Clinical Data Published at the American Society of Clinical Oncology 43rd Annual Meeting

CHICAGO, June 04, 2007 /PRNewswire-FirstCall/ -- Pharmion Corporation today released interim findings from its Phase II, multi-center clinical study of Amrubicin, the company's third-generation synthetic anthracycline currently in development for the treatment of small cell lung cancer. These findings indicate favorable interim results in terms of response rate and safety when comparing Amrubicin to the current treatment standard, topotecan, in second-line treatment of platinum-sensitive small-cell lung cancer patients with extensive disease (ED-SCLC). The early results of this study were published online on the ASCO website during the 43rd Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, Ill. (June 1- 5, 2007).

"Oncologists have very limited treatment options available for patients with extensive-disease small cell lung cancer, and regrettably, patients with this disease still have an exceptionally poor prognosis," said Andrew R. Allen, chief medical officer of Pharmion. "We are encouraged by these initial results which suggest Amrubicin's potential to improve the treatment landscape for small cell lung cancer."

The trial compares Amrubicin and topotecan in patients with ED-SCLC that initially responded to first-line platinum-based therapy but recurred or progressed at least 90 days after completion of first-line treatment. Study participants are randomized 2:1 to receive either Amrubicin (40 mg/m2 via 5- min.infusion daily x 3 days) or topotecan (1.5 mg/m2 via 30-min. infusion daily x 5 days), both starting on Day 1 of a 21-day cycle.

Response data from 24 evaluable patients have been analyzed, 15 treated with Amrubicin and nine with topotecan. Of the 15 Amrubicin patients, 40 percent showed an objective tumor response, including two complete r
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Clinical Study Shows Regenecare Relieves Pain and Itching of Skin Rashes Caused by Widely Used Cancer Drugs
2. International ENDORSE Study Shows That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE prophylaxis
3. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
4. MediGene Announces Cancer-Fighting Virus Shows Promise in Early Clinical Trial
5. Study Shows Ixabepilone Demonstrated Clear Activity in Patients with Metastatic Breast Cancer Resistant to Anthracycline, Taxane, and Capecitabine
6. Ceragenix Compound Shows Promise for Treating Lethal Cystic Fibrosis Infections
7. Largest Cervical Cancer Vaccine Efficacy Trial Shows Cervarix Provides Excellent Protection Against Lesions Caused by Most Common Cancer-Causing Virus Types
8. CombinatoRx Product Candidate CRx-150 Shows Activity on DAS28 and Pain, but Not CRP
9. New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir
10. First Phase II Short-Term Study on Dapagliflozin Shows Results on Safety, Tolerability and Glycemic Markers in Subjects With Type 2 Diabetes
11. New Poll Shows Men, Women Incorrectly Blame Symptoms of Low Testosterone on Normal Aging
Post Your Comments:
(Date:12/24/2014)... , Dec. 24, 2014  Diplomat Pharmacy, Inc. (NYSE: ... pharmacy, is proud to announce Jennifer Hagerman , ... Diplomat, will take office as the president of the ... induction ceremony will take place Feb. 28, 2015, at ... held at the Renaissance Center in Detroit, ...
(Date:12/24/2014)... KENNEWICK, Wash. , Dec. 23, 2014 /PRNewswire/ ... stage development company engaged primarily in the development ... and therapeutic applications, today announced that it has ... the Food and Drug Administration ("FDA") for marketing ... to Section 513(f)(2) of the U.S. Food, Drug ...
(Date:12/24/2014)... DALLAS , Dec. 23, 2014  Lockton ... operation of Lockton Companies, announced the addition of ... Foerster will join Lockton Dunning,s Pharmacy Consulting team, ... years of relevant industry experience to the position.  ... Managed Market Sales at Diplomat Specialty Pharmacy, where ...
Breaking Medicine Technology:Diplomat's senior director of education and quality to be inducted as 2015 president of the Michigan Pharmacists Association 2Diplomat's senior director of education and quality to be inducted as 2015 president of the Michigan Pharmacists Association 3Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 2Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 3Kim Foerster Joins Lockton Companies 2
... /PRNewswire-Asia-FirstCall/ -- China Medicine Corporation (OTC Bulletin Board: ... manufacturer, developer and distributor of Western pharmaceuticals, traditional ... the People,s Republic of China, today announced that ... to stockholder approval, the 2011 Long-Term Incentive Plan ...
... N.C., March 3, 2011 Recent ... Corporate governance changes announced Term loan repaid ... Fourth quarter 2010 financial results announced ... CSA ), healthcare,s preferred real estate partner, is a REIT ...
Cached Medicine Technology:China Medicine Corporation Adopts New Incentive Compensation Plans 2China Medicine Corporation Adopts New Incentive Compensation Plans 3Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 2Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 3Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 4Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 5Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 6Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 7Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 8Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 9Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 10Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 11Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 12Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 13Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 14Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 15Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 16
(Date:12/25/2014)... 2014 “Every three months the trends for ... sweetheart evening dress will be one of the hottest styles ... Yunx.co.uk says. Today, the company releases 26 A-line sweetheart evening ... 80% off. , “We are trying our best to ... our latest designs. Along with affordable prices, we provide discounted ...
(Date:12/25/2014)... CA (PRWEB) December 25, 2014 The short ... was created in honor of a true 9/11 hero, ... two film festivals including the 24 hours of Nuremberg International ... in Bangladesh. , Actress, screenwriter and director Luciana ... produce this film together with her husband, Gregory Graham ...
(Date:12/25/2014)... 25, 2014 Helen Harris’ RP (Retinitis ... Hills, California after an 8 year battle with breast ... Eve evening in her home in Woodland Hills California ... cancer. , As the founder and ... she pioneered and championed many of today's greatest breakthroughs ...
(Date:12/25/2014)... Thompson HealthDay Reporter WEDNESDAY, ... complex chronic illnesses can receive effective, less expensive care from ... access to a team of dedicated health care professionals, a ... seriously ill and need either hospitalization or a trip to ... medical home clinic at the University of Texas in Houston ...
(Date:12/25/2014)... -- Among early stage breast cancer patients who undergo ... percent will eventually develop leukemia as a result of ... comes from a review of more than 20,000 breast ... suggests that the risk for developing treatment-related leukemia, though ... "The frequency of bone marrow cancers such as ...
Breaking Medicine News(10 mins):Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 3Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 3Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 4Health News:Coordinated Care Through 'Medical Home' Best for Chronically Ill Kids: Study 2Health News:Coordinated Care Through 'Medical Home' Best for Chronically Ill Kids: Study 3Health News:Breast Cancer Chemo Tied to Small But Significant Leukemia Risk 2Health News:Breast Cancer Chemo Tied to Small But Significant Leukemia Risk 3
... Drug Spending Despite Higher Use - - Cancer ... - ... LAKES, N.J., May 15 Diabetes,treatments are now the leading driver ... a decade of,reigning in the top position, as generic drugs cut ...
... May 15 Alexza,Pharmaceuticals, Inc. (Nasdaq: ALXA ) ... during the Seventh Annual JMP Securities,Research Conference on Monday, ... the Citi Investment Research Global Healthcare Conference on Wednesday,May ... JMP presentation will be webcast from The Ritz-Carlton Hotel ...
... May 15 MS -- "Eat your vegetables!" is ... it that many young children,don,t seem to like vegetables? ... prenatally," says Jane Kostelc, early childhood specialist,at Parents as ... Pennsylvania State University shows that unborn babies may detect,taste ...
... UCLAs Jonsson Cancer Center and the Department of Urology have ... in a Western diet helps prevent prostate cancer in mice, ... that closely mimics human cancer, researchers said. , The study, ... journal Cancer Research, focused on fat from corn oil, which ...
... May 20, 2008 Transplantation of muscle-derived stem ... for patients suffering from urinary incontinence following a ... 103rd Annual Scientific Meeting of the American Urological ... from iatrogenic sphincter damage may benefit from this ...
... National Eating,Disorders Association (NEDA) and the Academy for ... rights, launching a statewide initiative,in Washington to help ... disorders., Entitled the Worldwide Charter for Action ... among patients, families and their,treatment team to ensure ...
Cached Medicine News:Health News:Diabetes Drugs Emerge as Top Force in Drug Spending Growth 2Health News:Diabetes Drugs Emerge as Top Force in Drug Spending Growth 3Health News:Diabetes Drugs Emerge as Top Force in Drug Spending Growth 4Health News:Diabetes Drugs Emerge as Top Force in Drug Spending Growth 5Health News:Alexza's Corporate Presentation to be Webcast at the Seventh Annual JMP Securities Research Conference and the 2008 Citi Investment Research Global Healthcare Conference 2Health News:Alexza's Corporate Presentation to be Webcast at the Seventh Annual JMP Securities Research Conference and the 2008 Citi Investment Research Global Healthcare Conference 3Health News:Eat Your Vegetables - That Means You, Parents! 2Health News:Reducing intake of dietary fat prevents prostate cancer in mice 2Health News:Eating Disorder Experts, Advocates Introduce Patient Bill of Rights To Ensure Quality Care in Washington State and Throughout U.S. 2
... Cross-match tubes are available ... serum tube contains a clotting ... cross-match tests where serum is ... EDTA cross-match tube is suitable ...
Inquire...
... K2 / gel tubes are for ... molecular diagnostics and for viral load ... blood remain stable at room temperature ... optimal results, it is recommended to ...
Glass Whole Blood Tube with K3EDTA...
Medicine Products: