Navigation Links
Pharmacyclics Announces Promising Results From Phase 2 Clinical,Trial of Xcytrin in Recurrent, Metastatic Non-Small Cell Lung,Cancer

- Data Support Rationale for Comprehensive Ongoing Phase 2 Program as Combination Agent with Standard Chemotherapies and Pivotal Lung Cancer Trial Scheduled to Begin Early Next Year -

CHICAGO and SUNNYVALE, Calif. June 01, 2007 /PRNewswire-FirstCall/ -- Pharmacyclics, Inc. today announced promising preliminary results from an open-label Phase 2 clinical trial of Xcytrin(R) (motexafin gadolinium) Injection, the company's lead cancer therapeutic candidate, as a second-line treatment for patients with recurrent, metastatic non-small cell lung cancer (NSCLC) who failed at least one platinum-based chemotherapy regimen. The results were published in the proceedings of the 2007 American Society of Clinical Oncology Annual Meeting (ASCO) taking place this week in Chicago.

"These results indicate that Xcytrin is an active, well-tolerated drug for treatment of recurrent NSCLC," said Richard A. Miller, M.D., president and CEO of Pharmacyclics. "The response rate and survival observed in this trial are comparable to currently approved second-line therapies for NSCLC and support our strategy to conduct multiple ongoing Phase 2 studies of Xcytrin in combination with standard therapies and move into a pivotal trial for this indication early next year. In addition, we are continuing to pursue our new drug application for Xcytrin to treat patients with brain metastases from NSCLC. We believe Xcytrin's selectivity, novel mechanism of action, magnetic resonance imaging detectability, and non-overlapping toxicity with other agents make it an appealing drug to study in combination with other therapies for a broad range of cancers."

The abstract, "A phase II trial of motexafin gadolinium (MGd) in advanced non-small cell lung cancer (NSCLC) patients who had failed platinum-based chemotherapy: Preliminary results of Stage 1," described interim results from a Phase 2 trial evaluating the safety, tumor response and duratio
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Pharmacyclics Announces Interim Results From Two Ongoing Phase 2 Trials Supporting Potential of Xcytrin Plus Chemotherapy to Treat Recurrent Non-Small Cell Lung Cancer
2. Pharmacyclics Announces Presentations and Published Abstracts on Xcytrin at The 2007 American Society of Clinical Oncology Annual Meeting
3. Pharmacyclics Identifies Functional Biomarkers for its Novel HDAC Inhibitor and Demonstrates Preclinical Anti-Tumor Activity with Brutons Tyrosine Kinase Inhibitors
4. Pharmacyclics Announces Presentations on Its Novel and Selective HDAC and Brutons Tyrosine Kinase Inhibitor Compounds
5. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
6. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
7. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
8. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
9. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
10. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
11. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
Post Your Comments:
(Date:7/31/2015)... 2015  In today,s ever-changing marketplace, call centers must ... increasingly connected, and increasingly impatient with slow service. The ... channels and tools is driving call centers to explore ... According to research by benchmarking firm, Best Practices, ... in a call center study realize the impact of ...
(Date:7/31/2015)... , July 31, 2015 Today, ... (NABP ® ) issued a report urging ... that action is taken against websites illegally selling ... Internet Drug Outlet Identification Program Progress Report for ... , thousands of websites illegally distribute medications ...
(Date:7/31/2015)... , July 31, 2015  Boston Children,s ... benefiting from 3D printing of their anatomy before ... life-threatening cerebrovascular malformations (abnormalities in the brain,s blood ... Reporting online today in the Journal of ... of 3D printing and synthetic resins to create ...
Breaking Medicine Technology:Best Practices in Building World-Class Consumer & Over-the-Counter Call Centers 2NABP Stresses Need for Accountability in Enforcing Internet Policies to Protect the Public From Illegal Online Drug Sellers 2NABP Stresses Need for Accountability in Enforcing Internet Policies to Protect the Public From Illegal Online Drug Sellers 33D Printing Helps Doctors Rehearse Complex Brain Procedures 23D Printing Helps Doctors Rehearse Complex Brain Procedures 33D Printing Helps Doctors Rehearse Complex Brain Procedures 4
... on-going effort to give back to the local community, The ... will donate $5,200 to the Greater Boston Food Bank. ... to loyal conference attendees in November of 2010, CBI included ... conference of choice. This year, in the spirit of Thanksgiving ...
... May 10, 2011 Roper Industries, Inc. ... it has signed a definitive agreement to acquire ... measurement technology for medical applications.  Northern Digital will ... Headquartered in Waterloo, Ontario, Canada, Northern Digital provides ...
Cached Medicine Technology:The Center for Business Intelligence Donates More than $5,000 to the Greater Boston Food Bank 2Roper Industries to Acquire Northern Digital, Inc. 2Roper Industries to Acquire Northern Digital, Inc. 3
(Date:8/1/2015)... TX (PRWEB) , ... August 01, 2015 , ... The ... concern among both men and women often causing pain and discomfort. Those who spend ... this circulatory problem, and Northeast Houston Vein Center is doing what it can to ...
(Date:8/1/2015)... ... ... Brig and Lita Hart, icons of the network marketing industry and founders of the ... HOPE Movement of EvolvHealth. In what has been a long-term relationship between the companies ... missions of purpose together to change the course of the network marketing industry. , ...
(Date:8/1/2015)... ... August 01, 2015 , ... Lume Wellness creators Alex, ... free to download on the Apple AppStore. , The app is designed to ... thus acting as a tool to view personal health and use this information for ...
(Date:8/1/2015)... ... ... 19, 2015 Phil Valentine – the Executive Director of Connecticut Community for Addiction Recovery (CCAR) ... Springer Mountain and heading north. Since that day, Phil has hiked over 1400 miles in ... friends and family. He visited CCAR and left an inspirational message to his staff: ...
(Date:7/31/2015)... ... 31, 2015 , ... When the weather turned hot and warm-season turfgrasses, such ... sod called Leisure Time(TM) zoysia . It's nicknamed LTZ(TM) for short. Incidentally, both ... this new type of sod, Super-Sod is giving away red Adirondack chairs with the ...
Breaking Medicine News(10 mins):Health News:Northeast Houston Vein Center Warns Men about Varicose Veins 2Health News:Northeast Houston Vein Center Warns Men about Varicose Veins 3Health News:Looking for HOPE? Healthy Home Has Evolv’d 2Health News:Looking for HOPE? Healthy Home Has Evolv’d 3Health News:Lume Wellness Launches Health and Fitness Tracker iPhone App 2Health News:Connecticut Executive Hikes Appalachian Trail to Raise Awareness About Recovery. 2Health News:Super-Sod Introduces Leisure Time(TM) Zoysia Grass with an Adirondack Chair Promotion 2
... study suggests that extra iron for infants who don,t need ... over optimal iron supplement levels and could have huge implications ... for 25 years of research show problems with lack of ... deal, it,s really unexpected," said Dr. Betsy Lozoff, University of ...
... Actress Joins Thousands of Participants in Inspirational Closing ... Local Breast Cancer Organizations, WASHINGTON, May 4 ... Foundation Reese Witherspoon was a special guest at ... D.C. this weekend,cheering on and joining walkers on ...
... 2008 Annual Meeting in San,Diego, CA, NEW YORK, ... MD, is the new President of the American Society ... 2,400,members, is the leading national organization of board-certified plastic,surgeons ... The,election of new officers was held on May 4, ...
... parents have a surprisingly low-level knowledge of typical ... physical, social and emotional growth, according research from ... suggest that such false parenting assumptions can not ... of much-needed cognitive stimulation, will be presented Sunday, ...
... always connected, researchers say , , FRIDAY, May 2 (HealthDay ... experienced by Alzheimer,s disease patients and the sleep woes ... from the University of Washington, in Seattle, found that ... always connected. , The researchers studied 44 older adults, ...
... Ripping out and tearing down to create a divinely ... and the economic downturn may be leading more families ... has found that parents need to be aware that all ... due to exposure to lead. , The study ...
Cached Medicine News:Health News:Iron supplements might harm infants who have enough 2Health News:Reese Witherspoon Helps Celebrate Avon Walk for Breast Cancer Washington, D.C. - Weekend-Long Event Raises $8.1 Million 2Health News:Reese Witherspoon Helps Celebrate Avon Walk for Breast Cancer Washington, D.C. - Weekend-Long Event Raises $8.1 Million 3Health News:Reese Witherspoon Helps Celebrate Avon Walk for Breast Cancer Washington, D.C. - Weekend-Long Event Raises $8.1 Million 4Health News:Reese Witherspoon Helps Celebrate Avon Walk for Breast Cancer Washington, D.C. - Weekend-Long Event Raises $8.1 Million 5Health News:Reese Witherspoon Helps Celebrate Avon Walk for Breast Cancer Washington, D.C. - Weekend-Long Event Raises $8.1 Million 6Health News:Long Island Plastic Surgeon is New President of American Society for Aesthetic Plastic Surgery 2Health News:Long Island Plastic Surgeon is New President of American Society for Aesthetic Plastic Surgery 3Health News:Nearly one-third of US parents don't know what to expect of infants 2Health News:Sleep Troubles Vary Between Alzheimer's Patients, Caregivers 2Health News:Fixing up 'this old house' may increase young 2Health News:Fixing up 'this old house' may increase young 3
Pipetman P is a fully adjustable, air-displacement pipette with the selected volume shown on a digital indicator (volumeter). Eight models cover the full range of volumes from 0.2 L to 10 mL....
... improved ergonomics for today's exacting laboratory ... finger rest and the large display ... Finnpipette Digitals also feature soft-touch tip ... pend.) and super blow-out for 0.2 ...
This CLS number is a new product number, created to easily match Cornings product number. If showing no availability yet, please order under the old Sigma-Aldrich number (Z71,408-9) or contact custom...
Research Series 2100 Adjustable-volume Pipette, 10-100 l, single-channel with adjustable-volume setting...
Medicine Products: