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Pharmacyclics Announces Presentations and Published Abstracts on,Xcytrin at The 2007 American Society of Clinical Oncology Annual,Meeting

SUNNYVALE, Calif., May 23, 2007 /PRNewswire-FirstCall/ -- Pharmacyclics, Inc. announced today multiple presentations and a published abstract regarding Xcytrin(R) (motexafin gadolinium) Injection, including an oral presentation of Phase 3 SMART (Study of Neurologic Progression with Motexafin Gadolinium And Radiation Therapy) trial data. The presentations and publications are part of the proceedings at the 2007 American Society of Clinical Oncology Annual Meeting (ASCO) that will be held June 1-5, 2007, at McCormick Place in Chicago, IL.

    The presentations and published abstracts are as follows:


    Sunday, June 3, 2007

    Session: Central Nervous System Tumors

    Oral Presentation: Motexafin gadolinium (MGd) combined with whole brain

    radiation therapy prolongs time to neurologic progression in non-small

    cell lung cancer (NSCLC) patients with brain metastases: Pooled analysis

    of two randomized phase III trials. Abstract #2010: 3:00 - 3:15 p.m.


    Location: S100a

    Presenter: William Shapiro, M.D., Barrow Neurological Institute,

    Phoenix,AZ


    Session: Central Nervous System Tumors


    Poster Presentation: Identification of occult brain metastases amenable to

    stereotactic radiosurgery by motexafin gadolinium (MGd) based treatment

    planning MRI: Results of a phase II trial of MGd and whole brain

    radiotherapy (WBRT) with stereotactic radiosurgery (SRS).

    Abstract #2037: 8:00 a.m. - 12:00 p.m.;

    Discussion: 11:00 a.m. - 12:00 p.m.


    Poster Display Location: S102a; Discussion: S100a

    Presenter: Minesh P. Mehta, M.D., University of Wisconsin


    Motexafin Gadolinium Published Abstract

    Abstract #18001

    Title: A phase II trial of motexafin gadolinium (MGd) in advanced

    non-small-cell lung cancer (NSCLC) patients who had failed platinum-based

    chemotherapy: Preliminary results of Stage 1

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