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Peramivir Protects Mice From Lethal H5N1 Infection

"We are currently studying the emergence of H5N1 variants that are resistant to this drug and may occur in the course of treatment," said Natalia A. Ilyushina, Ph.D., a postdoctoral fellow in Webster's laboratory and a co- author of the paper.

Other authors of this report include Robert G. Webster (St. Jude) and C. Shane Arnold and Y. Sudhakar Babu (BioCryst Pharmaceuticals Inc., Birmingham, Ala.).

This study was supported by National Institute of Allergy and Infectious Diseases, the U.S. Public Health Service, BioCryst Pharmaceuticals and ALSAC.

St. Jude Children's Research Hospital

St. Jude Children's Research Hospital is internationally recognized for its pioneering work in finding cures and saving children with cancer and other catastrophic diseases. Founded by late entertainer Danny Thomas and based in Memphis, Tenn., St. Jude freely shares its discoveries with scientific and medical communities around the world. No family ever pays for treatments not covered by insurance, and families without insurance are never asked to pay. St. Jude is financially supported by ALSAC, its fundraising organization. For more information, please visit http://www.stjude.org.

CONTACT: Carrie Strehlau, Public Relations, +1-901-495-2295,, or Summer Freeman, Public Relations,+1-901-495-3061, , or Marc Kusinitz, Ph.D.,Scientific Communications, +1-901-495-5020, , allof St. Jude Children's Research Hospital carrie.strehlau@stjude.org summer.freeman@stjude.org marc.kusinitz@stjude.org

Web site: http://www.stjude.org/

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