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PDL BioPharma Announces Long-Term Nuvion Data Presented at 2007,Digestive Disease Week

atment for inflammatory bowel diseases:

    -- On Monday, May 21, Lloyd F. Mayer, M.D., Professor and Chairman of the

       Immunobiology Center, Professor of Medicine and Chief of the Divisions

       of Clinical Immunology and Gastroenterology at the Mount Sinai School

       of Medicine in New York, presented results of a study (Abstract M1679)

       demonstrating that in in vitro culture experiment, the Nuvion antibody

       induced expansion of CD8+ T cells, and the CD8+ T cells possessed

       regulatory T cell activity.  If confirmed in human studies, this

       mechanism may contribute to the observed long-term response to the

       Nuvion antibody in some patients with IVSR-UC, Dr. Mayer concluded.


    -- On Wednesday, May 23, Daniel C. Baumgart M.D., Charite Medical Center,

       Virchow Hospital, Berlin, Germany, will deliver an oral presentation of

       data supporting the efficacy and safety of the Nuvion antibody in

       patients with moderate-to-severe, refractory Crohn's disease (Abstract

       1032).  The data from this study are intriguing, and PDL is assessing

       options for further study in this patient population.

About PDL BioPharma

PDL BioPharma, Inc. is a biopharmaceutical company focused on discovering, developing and commercializing innovative therapies for severe or life- threatening illnesses. Commercially focused in the acute-care hospital setting, PDL markets and sells its portfolio of products in the United States and Canada. A pioneer of antibody humanization technology, PDL promotes this technology through licensing agreements and clinical development of its own diverse pipeline of investigational compounds. PDL's research platform centers on the discovery and development of antibodies to treat cancer and autoimmune diseases. For more information, please visit www.pdl.com.

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Gentamicin Reagent Solution (10 mg/ml) liquid
LB Agar plates with 0.1mM EDTA.
Luria bertani broth: 1.0% Tryptone, 0.5% Yeast Extract, 1.0% Sodium Chloride.
2.5% Soytone, 4.8% Yeast Extract, 0.025% Magnesium Sulfate, 130mM Calcium Chloride.
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