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Orexigen Therapeutics to Present Data on Contrave Impact on,Visceral Fat and Insulin Resistance at American Diabetes,Association 67th Scientific Sessions in Chicago June 23

his cautionary statement and Orexigen undertakes no obligation to revise or update this news release to reflect events or circumstances after the date hereof. This caution is made under the safe harbor provisions of Section 21E of the Private Securities Litigation Reform Act of 1995.

    CONTACTS:

    OREXIGEN                    MEDIA                    INVESTORS

    Graham Cooper               Stephen Gendel           Jason Spark

    858 436-8600                212 918-4650             619 849-6005

CONTACT: Graham Cooper, +1-858-436-8600, Stephen Gendel, +1-212-918-4650Jason Spark, +1-619-849-6005, all for Orexigen(TM) Therapeutics, Inc.

Web site: http://www.Orexigen.com/

Ticker Symbol: (NASDAQ-NMS:OREX)

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