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OncoGenex and Isis Announce OGX-011 Data to be Presented at ASCO

facts and factors currently known by Isis. As a result, you are cautioned not to rely on these forward-looking statements. These and other risks concerning Isis' programs are described in additional detail in Isis' annual report on Form 10-K for the year ended December 31, 2006, and its quarterly report on Form 10-Q for the quarter ended March 31, 2007, which are on file with the SEC. Copies of this and other documents are available from the Company.

    Isis Pharmaceuticals, Ibis Biosciences and Ibis T5000 are registered

    trademarks or trademarks of Isis Pharmaceuticals, Inc.


CONTACT: OncoGenex Contact: Scott Cormack, President & CEO, (604) 630-5400; OncoGenex Media Contact: Jason Spark, Porter Novelli Life Sciences, (619) 849-6005; Isis Contact: Kate Corcoran, Vice President, Corporate Development, (760) 603-2331

CONTACT: OncoGenex Contact: Scott Cormack, President & CEO, (604)630-5400; OncoGenex Media Contact: Jason Spark, Porter Novelli LifeSciences, (619) 849-6005; Isis Contact: Kate Corcoran, Vice President,Corporate Development, (760) 603-2331

Ticker Symbol: (NASDAQ-NMS:ISIS)

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