Navigation Links
Once-Fatal Metabolic Disorders Treatable, Says Stanford/Packard,Researcher

le outcome."

Alternative pathway therapy includes a combination of two drugs that work to help the body rid itself of excess nitrogen: sodium phenylacetate and sodium benzoate. Metabolic disease expert Saul Brusilow, MD, at Johns Hopkins' Children's Center, pioneered the drug combination in the 1970s as a possible treatment for urea cycle disorders. Although early reports showed promising results, it took years to gather enough patients to prove the treatment's effectiveness.

Prompt treatment does more than just save lives, however. It also protects patients' brains and gives them a chance at a normal life.

"Traditionally, the cognitive outcome of these disorders has been horrible," said Enns. "There were ethical arguments to be made about even trying to help these kids. The rationale was 'Why treat if you're going to be left with a child who can't do anything?' Now we've shown that we can save these kids."

He added, "Although there are still significant hurdles to overcome--in particular, timely diagnosis--at least we know that normal intelligence is possible. All is not lost when a family gets this diagnosis."

The study was supported by grants from the General Clinical Research Centers at Johns Hopkins University, Children's Hospital of Philadelphia, and Children's National Medical Center; grants from the National Institute of Child Health and Human Development, the Food and Drug Administration, the National Center for Research Resources, and through support of the national General Clinical Research Network.

Sodium phenylacetate and sodium benzoate are marketed for the treatment of urea cycle disorders by Ucyclyd Pharma under the trade name Ammonul. Enns has received a lecture fee from Ucyclyd Pharma and a consulting fee from Ucyclyd Pharma for service at one meeting of the advisory board of the company.

Stanford University Medical Center integrates research, medical education and patient care at its three instituti
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Lipitor Provides Unprecedented Cardiovascular Risk Reductions in Diabetes Patients with Metabolic Syndrome and in Stroke Patients
2. Study Presented at the ACC Shows Inflammatory Enzyme Lp-PLA2 Predicts Heart Disease Risk in Metabolic Syndrome Patients
3. Study Shows Metabolic Strategy of Stressed Cell
4. IMPAX Presents at Movement Disorder Societys 11th International Congress of Parkinsons Disease and Movement Disorders
5. Faust Pharmaceuticals Phase IIa Results for Parkinsons Disease Presented at International Congress of Parkinsons Disease and Movement Disorders
6. Cogane Data Presented at ‘11th International Congress of Parkinson’s Disease and Disorders’
7. Targeting Specific Mutations Reveals Promising New Approach to Treating Genetic Disorders; Preclinical Data Published in Nature
Post Your Comments:
(Date:12/17/2014)... , Dec. 17, 2014 PCCA received ... ( http://bit.ly/1382OkS ) program seal for best ... The program highlights medical practices, materials and goods ... friendly." Children affected by autism often ... be exacerbated by ingredients found in food and ...
(Date:12/15/2014)... DUBLIN , Dec. 12, 2014 Research ... announced the addition of the "MEMS Gyroscopes ... Costing Analysis" report to their offering. ... MEMS gyroscopes for tactical grade applications made a ... in term of reliability. They are now accepted ...
(Date:12/15/2014)... DUBLIN , Dec. 12, 2014 Research and ... addition of the "Inferior Vena Cava (IVC) Filters ... to their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... sector is projected to reach US$435 million by 2016. ... nearly 39% (2015) of the global value while ...
Breaking Medicine Technology:Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 2Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 3MEMS Gyroscopes Analog Devices ADIS16136 Precision Angular Rate Sensor Reverse Costing Analysis 2Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 2Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 3Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 4
(Date:12/19/2014)... NJ (PRWEB) December 19, 2014 ... Inside Patient Care: Pharmacy & Clinics™, an independent ... healthcare team treating and caring for patients inside ... primary care expands to provide optimal access to ... offers a forum for the team treating and ...
(Date:12/19/2014)... (PRWEB) December 19, 2014 ... the diagnostic, personalized medicine, healthcare information technology, and ... the position of Chief Operating Officer. The announcement ... Partners, marked by a strengthened presence in Boston ... , "Leslie lives and breathes the client experience," ...
(Date:12/19/2014)... (HealthDay News) -- Being in good shape seems to reduce ... looked at data from more than 57,000 Americans, including more ... between 1991 and 2009. Those in the poorest shape ... blood pressure at the start of the study, compared to ... fitness. Of the more than 8,000 people diagnosed with ...
(Date:12/19/2014)... Traveling through the same U.S. airport gate, one infected ... a four-hour time span, illustrating just how easily the ... exposures in this report were not prolonged and occurred ... the fact that measles is highly contagious," wrote a ... at the U.S. Centers for Disease Control and Prevention. ...
(Date:12/17/2014)... 2014 Unidesk Corporation today announced ... which welcomed its inaugural class in August 2013, ... seamlessly support bring your own device (BYOD) and ... experience. The solution, comprised of Citrix XenDesktop ... server and storage infrastructure and Unidesk ...
Breaking Medicine News(10 mins):Health News:The Transformation of Retail Pharmacies into a Healthcare Delivery Center 2Health News:The Transformation of Retail Pharmacies into a Healthcare Delivery Center 3Health News:Slone Partners Promotes Leslie Loveless to Chief Operating Officer 2Health News:Being Fit Keeps Blood Pressure in Check 2Health News:Arriving Now at Gate 42: Measles 2Health News:Arriving Now at Gate 42: Measles 3Health News:Alabama College of Osteopathic Medicine Deploys Desktop Virtualization Solution from Citrix, Dell and Unidesk 2Health News:Alabama College of Osteopathic Medicine Deploys Desktop Virtualization Solution from Citrix, Dell and Unidesk 3
... Health Reform, Progressives Hail Choice of HHS Secretary and White ... America,s Future co-director Roger Hickey congratulated President ... Sebelius , D-Kansas, to be secretary of health and human ... of the White House Office for health Reform. Hickey praised ...
... Corporation (NYSE: HLS ) today announced it ... on March 10-11, 2009, at the Loews Miami Beach ... Officer Jay Grinney and Executive Vice President and Chief ... March 10, at 9:30 a.m. EDT. The presentation will ...
... seems to play a role, study finds, , , MONDAY, ... increases the risk of suicide in young adults, says ... for 15 years after they started first grade in ... the participants when they were young adults (average age ...
... InjunctionWASHINGTON, March 2 The United States has ... its subsidiaries, ETHEX Corp. and Ther-Rx Corp., and ... and unapproved drugs, the Justice Department announced today. ... injunction in a consent decree. The FDA conducted ...
... 2 /PRNewswire-Asia-FirstCall/ -- China Nepstar,Chain Drugstore Ltd. (NYSE: ... drugstore chain in China based on the number of ... the fourth quarter and,fiscal year 2008 financial results ended ... 16, 2009. , The Company ...
... warn parents that instruction alone is no guarantee , , ... in swimming lessons doesn,t increase their risk of drowning, ... health professionals that swimming lessons could actually increase drowning ... youngsters are in and around water. , U.S. ...
Cached Medicine News:Health News:Praise for Sebelius, DeParle From Campaign for America's Future Co-Director Roger Hickey 2Health News:Post-Traumatic Stress Tied to Increased Suicide Risk 2Health News:United States Files Suit Against Missouri-Based Pharmaceutical to Block Manufacturing and Shipping of Unapproved Drugs 2Health News:China Nepstar Chain Drugstore to Announce Fourth Quarter and Fiscal 2008 Financial Results on March 16 2Health News:Swimming Lessons Don't Increase Drowning Risk, Study Says 2
All Keeler magnifiers and telescope are available on a clip to fit over the patient's own spectacle...
A simple testing set for prescribing aspheric spectacle magnifiers. Redi-glaze lenses are available for instant dispensing which are cut and edged to fit our standard LVA frame....
Significantly more compact and tidier in overall looks yet retain many of the excellent features of the more comprehensive Haag type systems., ,Filters include Cobalt blue; green (red free); neut...
... to 20 tilting tower ... the vertical, horizontal and ... option to offset the ... ,Filters include Cobalt blue; ...
Medicine Products: