Navigation Links
Once-Fatal Metabolic Disorders Treatable, Says Stanford/Packard,Researcher

amage, coma and death.

If a diagnosis is made quickly enough, dialysis can help to cleanse the blood of excess nitrogen during an episode and prevent brain damage.

Traditional treatments included maintaining a very-low protein diet that is still high enough in calories to avoid metabolizing any of the body's protein-rich muscle. Liver transplantation is also an option for some patients.

This study investigated whether drugs that promote alternative pathways to dismantle and excrete nitrogen-containing waste can lower the dangerously high levels of blood ammonia, called hyperammonemia.

The 299 people in the study experienced 1,181 episodes of hyperammonemia during the study period. Those who received the drug therapy had an overall survival rate of 73 percent for newborns and 98 percent for older patients. In contrast, a recent European study of 217 patients who did not receive the therapy reported overall survival rates of only 16 percent for newborns and 72 percent for people with later onset of disease.

Urea cycle disorders can become apparent at many different stages in life. Newborns with a complete blockage in the cycle begin to show symptoms within hours after birth but are often misdiagnosed. Older children or adults with less-severe mutations can lead normal lives until sickness or a change in diet overtax the body and bring on a life-threatening episode.

Only a fraction of the many possible mutations are picked up by expanded newborn screening, and precious days are lost while test results are processed. The lethargy, vomiting and rapid breathing exhibited by affected newborns are often misinterpreted and mistreated as hospital-acquired infections. "Newborn screening is good at detecting some urea cycle disorders, but we can't diagnose all of them this way," said Enns. "By the time the results come back, these kids are already in the hospital and going into a coma. The sooner you identify them, the better the possib
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Lipitor Provides Unprecedented Cardiovascular Risk Reductions in Diabetes Patients with Metabolic Syndrome and in Stroke Patients
2. Study Presented at the ACC Shows Inflammatory Enzyme Lp-PLA2 Predicts Heart Disease Risk in Metabolic Syndrome Patients
3. Study Shows Metabolic Strategy of Stressed Cell
4. IMPAX Presents at Movement Disorder Societys 11th International Congress of Parkinsons Disease and Movement Disorders
5. Faust Pharmaceuticals Phase IIa Results for Parkinsons Disease Presented at International Congress of Parkinsons Disease and Movement Disorders
6. Cogane Data Presented at ‘11th International Congress of Parkinson’s Disease and Disorders’
7. Targeting Specific Mutations Reveals Promising New Approach to Treating Genetic Disorders; Preclinical Data Published in Nature
Post Your Comments:
(Date:8/29/2014)... 29, 2014 Research and Markets ... Instrument Industry Report, 2014-2017" report to their offering. ... rising proportion of reimbursement for medical expenses, the Chinese ... its scale presenting a CAGR of 19.2% during 2009-2013. ... product segments of orthopedic instruments in China ...
(Date:8/29/2014)... , August 29, 2014 ... Oil Market by Extraction type (SFE, Cold Pressed, ... Personal Care, Pharmaceutical, Food Supplements, Fragrance, & Others) - ... MarketsandMarkets, defines and segments the Amaranth Seed Oil ... market size in terms of value. The Amaranth ...
(Date:8/29/2014)... , Aug. 29, 2014  United Therapeutics Corporation ... U.S. District Court for the District of ... in the company,s case against Sandoz, Inc. regarding United ... Peter Sheridan ruled that U.S. Patent No. 6,765,117 ... enjoined Sandoz from marketing its generic product until the ...
Breaking Medicine Technology:China Orthopedic Instrument Industry Report, 2014-2017 2Amaranth Seed Oil Market worth $700.6 Million by 2019 2Amaranth Seed Oil Market worth $700.6 Million by 2019 3Amaranth Seed Oil Market worth $700.6 Million by 2019 4District Court Decision Received In Remodulin Patent Case 2
... , MONMOUTH JUNCTION, N.J., Oct. 19 Transave Inc., ... lead investigational drug, ARIKACE(TM) (liposomal amikacin for inhalation), an ... The latest results along with previously reported data demonstrate ... program in two indications - for the treatment of ...
... WORTH, Texas, Oct. 19 Galderma Laboratories proudly announces ... Cetaphil® UVA/UVB Defense SPF 50 have recently been granted ... Good Housekeeping Research Institute. , The Good Housekeeping Seal ... "tested and approved" emblems in the U.S. , "It ...
Cached Medicine Technology:Transave Completes Successful Phase II Clinical Program for ARIKACE in the Treatment of Pseudomonas Lung Infections 2Transave Completes Successful Phase II Clinical Program for ARIKACE in the Treatment of Pseudomonas Lung Infections 3Transave Completes Successful Phase II Clinical Program for ARIKACE in the Treatment of Pseudomonas Lung Infections 4Transave Completes Successful Phase II Clinical Program for ARIKACE in the Treatment of Pseudomonas Lung Infections 5Three Cetaphil(R) Products Earn Good Housekeeping Seal 2
(Date:8/30/2014)... The SI Joint Evaluation and Treatment covers ... energy techniques. Michael P. Reiman PT, DPT, OCS, SCS, ... for the SI Joint. This PT online ... presentation with North American Seminars. , PT ... differential diagnosis approach to a thorough examination of the ...
(Date:8/30/2014)... What challenges exist in recruiting top talent ... concerns, and considerations? Sports Conflict Institute ’s ... with Woody Wommack, Southeast Football Recruiting Analyst of Rivals.com/Yahoo! ... recruiting. Notably, Wommack spoke on what the recruiting ... thinks are coming as a result of the O’Bannon ...
(Date:8/30/2014)... 30 August 2014: A new sudden death predictor ... for implantable cardioverter defibrillators (ICDs) in ESC Guidelines ... by Task Force Chairperson Professor Perry Elliott (UK). ... Management of Hypertrophic Cardiomyopathy" are published today on-line ... and on the ESC Website. Previous ESC Guidelines ...
(Date:8/29/2014)... Cancer is a life-changing illness that ... Eddie M. Leung knows the suffering that patients go through; ... cancer, a very rare and aggressive form of cancer. In ... by Xlibris), he shares a glimpse into his struggles as ... testimony that this disease can be overcome. , ...
(Date:8/29/2014)... Denver, Colorado (PRWEB) August 29, 2014 Daily Gossip ... the program was created by a former cold sores patient who ... this method is Ellie Gadsby, who decided to share her tips ... the world. , The author of the Get Rid of ... sores for 22 years, while in the least 4 years outbreaks ...
Breaking Medicine News(10 mins):Health News:North American Seminars Online PT Continuing Education Course, Examination and Treatment of the SI Joint, Receives Continuing Education Approval in NJ, CA, IL, PA, & TX 2Health News:Woody Wommack of Rivals.com Discusses the World of NCAA Football Recruiting on SCI TV 2Health News:Woody Wommack of Rivals.com Discusses the World of NCAA Football Recruiting on SCI TV 3Health News:Sudden death predictor identifies ICD candidates in new ESC Guidelines 2Health News:Eddie M. Leung Shares His Testimony As a Survivor of Cancer 2Health News:Eddie M. Leung Shares His Testimony As a Survivor of Cancer 3Health News:Get Rid of Cold Sores Fast Review Reveals Simple Way to Eliminate Cold Sores in 12 Hours 2
... Hill-Rom Holdings, Inc. (NYSE: HRC ) today ... share. This dividend was declared by Hill-Rom,s Board of Directors ... 2009 to shareholders of record as of March 17, 2009. ... is a leading worldwide manufacturer and provider of medical technologies ...
... potential partners is easier to read than women,s, speed-dating study ... unattached this Valentine,s Day and you,re hoping to change that, ... easier to judge how interested a man is than it ... , Men who are attracted to women, it seems, are ...
... SYDNEY, Feb. 13 /PRNewswire-,FirstCall/ -- Thoratec Corporation ... leader in device-,based mechanical circulatory support therapies ... HeartWare International (ASX: HIN), which develops and,manufactures ... they,have entered into a definitive merger agreement ...
... through. , ... (Vocus) February 13, 2009 -- For centuries Mardi Gras - also known ... last bits of fat and meat in millions of homes in preparation for ... favorite foods. Meat is often chosen for this observance, as indicated by ...
... The Ensign Group, Inc. (Nasdaq: ... group of skilled nursing, rehabilitative care services and ... to issue its fourth quarter and fiscal year ... Wednesday, February 18, 2009.(Logo: http://www.newscom.com/cgi-bin/prnh/20071213/LATH168LOGO ) ...
... also affect chances of having debilitating headaches , , THURSDAY, Feb. ... of migraine headaches in young and middle-aged adults, suggests a ... and the way body fat was distributed affected migraine risk. ... more likely to have migraines than those with smaller waistlines. ...
Cached Medicine News:Health News:Men, the Obvious Sex 2Health News:Men, the Obvious Sex 3Health News:Thoratec Announces Definitive Agreement to Acquire HeartWare International For US$282 Million; 2Health News:Thoratec Announces Definitive Agreement to Acquire HeartWare International For US$282 Million; 3Health News:Thoratec Announces Definitive Agreement to Acquire HeartWare International For US$282 Million; 4Health News:Thoratec Announces Definitive Agreement to Acquire HeartWare International For US$282 Million; 5Health News:Thoratec Announces Definitive Agreement to Acquire HeartWare International For US$282 Million; 6Health News:Thoratec Announces Definitive Agreement to Acquire HeartWare International For US$282 Million; 7Health News:Mardi Gras Gives Everyone a Big Fat Break Because Carnival Means "So Long" to Meat 2Health News:Mardi Gras Gives Everyone a Big Fat Break Because Carnival Means "So Long" to Meat 3Health News:The Ensign Group Schedules 2008 Year End Earnings Call for Thursday, February 19, 2009 2Health News:Belly Fat May Make Migraines More Likely 2
... a combination of innovative design, consistently reliable ... I-125 implant an ideal choice for your ... every BrachySource I-125 implant order is backed ... required by clinicians who must meet the ...
... BrachySource iodine-125 implant is a combination of ... visibility that makes BrachySource I-125 implant an ... can be confident that every BrachySource I-125 ... management services which is required by clinicians ...
The silicone Tractfinder provides excellent fluoroscopic visualization. Manipulation of the movable core guidewire flexes the tapered proximal tip for maximum control in negotiating a tortuous ureter...
... Used for temporary internal drainage from the ... of a stricture. The segment with no ... lumen while preventing ingrowth of the ureteral ... peel-open packages. Intended for one-time use. CAUTION: ...
Medicine Products: