Navigation Links
OXiGENE Announces a Poster Presentation Highlighting Results from,its Study of ZYBRETSTAT CA4P in Myopic Macular Degeneration (Study,MMD-213) at the 47th Annual Meeting of the Association of Research,in Vision and Ophthalmology

WALTHAM, Mass.--(BUSINESS WIRE)--May 7, 2007 - OXiGENE, Inc. (NASDAQ: OXGN, XSSE: OXGN), a clinical-stage biotechnology company developing novel therapeutics to treat cancer and eye diseases, announced today that the results of its Phase II combretastatin A4 phosphate (CA4P) clinical trial in myopic macular degeneration (MMD) was presented at the 47th Annual Meeting of the Association of Research in Vision and Ophthalmology (ARVO) in Fort Lauderdale, FL. The abstract may be viewed at www.arvo.org.

The following are the poster session details: -0-

Poster No.:   1457/B534

Abstract      Phase II Clinical Trial of Intravenous Combretastatin A4

 Title:        Phosphate in Patients With Subfoveal Choroidal

               Neovascular Membranes (CNV) in Pathologic Myopia

Presentation  Monday, May 07, 2007, 8:30 AM -10:15 AM

 Time:

The poster provided additional details from the ZYBRESTAT(TM) CA4P Phase II clinical trial (MMD-213) in Myopic Macular Degeneration, top-line results from which the Company previously announced on February 15, 2007. Based on the positive results from this study, in which 100% of patients met the primary endpoint of maintenance of visual acuity, the Company has held a pre-IND meeting with the FDA regarding topical ophthalmic formulations (eye drops and ocular mini-tabs), is proceeding with development of a topical formulation of ZYBRESTAT(TM), and anticipates filing and IND and initiating clinical studies with the formulation in early 2008.

About the Study (MMD-213):

MMD-213 was a Phase II, double-masked (physician and subject), dose-ranging, multi-center study designed to evaluate the safety and efficacy of intravenous CA4P for treating subfoveal choroidal neovascularization in subjects with pathologic myopia. Subjects were assigned to receive CA4P at doses of 27, 36 or 45 mg/m(2). A total of 23 subjects, 7-8 per arm, were enrolled. All subjects receive
'"/>




Page: 1 2 3

Related medicine technology :

1. OXiGENE Abstracts Published in ASCO Program
2. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
3. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
5. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
6. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
7. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
8. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
9. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
10. Protox Announces Positive Clinical Data from Prostate Cancer Study
11. Inspire Announces Webcast of Presentation at C.E. Unterberg, Towbin Emerging Growth Opportunities Conference

Post Your Comments:
(Date:11/24/2009)...swire/--Accumetrics,Inc.,aprivately-helddevelopera...andeasy-to-usediagnosticsystemformeasuringanindivi...vix®andaspirin),announcedtodaythatTimothyI.St...tts,ChiefFinancialOfficerofAccumetrics,willbeprese...HealthCareConferencebeingheldinNewYorkCityonDecemb...
(Date:11/24/2009)...swire/--AmbitBiosciencesCorporationannouncedtodayt...,anovelsecondgenerationFLT3inhibitor,inAMLatthe51s...heldinNewOrleans,LA,December5-8,2009.Anoralpresent...eImonotherapysafetystudyinadultswithacutemyeloidle...sentedevaluatingtheeffectofAC220monotherapyandinco...
(Date:11/24/2009)...wire-Asia-FirstCall/--LotusPharmaceuticals,Inc.,(O...ngdeveloperand,producerofprescriptionsdrugsandlice...ople,sRepublicChina,todayreporteditwillexhibitatth...ldelegation. ,, Time:November26-28,2009 ,,..., TheBeijingdelegationfeaturesmorethantwentyphar...
Breaking Medicine Technology:Accumetrics to Present at the 21st Annual Piper Jaffray Health Care Conference 2Ambit Biosciences Corporation Announces Presentations Profiling AC220 Clinical and Non-Clinical Data at 51st American Society of Hematology Annual Meeting 2Ambit Biosciences Corporation Announces Presentations Profiling AC220 Clinical and Non-Clinical Data at 51st American Society of Hematology Annual Meeting 3Lotus Pharmaceuticals, Inc. to Exhibit at the 62nd PHARMCHINA 2A Wound that Does Not Heal 3A Frost 26 Sullivan Reveals the Impact of Chronic Ulcers on the European Healthcare System 55241 1A Wound that Does Not Heal 3A Frost 26 Sullivan Reveals the Impact of Chronic Ulcers on the European Healthcare System 55241 2Healthcare Education and Clean Energy Cited as In Demand Jobs of Tomorrow 55239 1Healthcare Education and Clean Energy Cited as In Demand Jobs of Tomorrow 55239 2Healthcare Education and Clean Energy Cited as In Demand Jobs of Tomorrow 55239 3American Medical Association Launches e Book Strategy with iPublishCentral from Impelsys 55237 1American Medical Association Launches e Book Strategy with iPublishCentral from Impelsys 55237 2American Medical Association Launches e Book Strategy with iPublishCentral from Impelsys 55237 3
...lore the Effects of Eligen(R) Delivery Technology ...en, CEDAR KNOLLS, N.J., June 30 Emisphere,Techno... Novartis Pharma AG,has launched a Phase I study i... tolerability of oral PTH134, a combination of hum...ng Emisphere,s proprietary Eligen(R),technology, f...
...une 30 DURECT Corporation,(Nasdaq: DRRX ) announ...,(FDA) has granted to DURECT orphan drug designati...ssociated with post-herpetic neuralgia (PHN).,Bupi... ELADUR(TM), DURECT,s,investigational transdermal ...duct approved for PHN, under the 1983 Orphan Drug ...
Other Medicine Technology:Emisphere Technologies Announces the Launch of a Human Clinical Trial For Oral Parathyroid Hormone (PTH) 2ELADUR(TM) Development Update: DURECT Receives Orphan Drug Designation for Bupivacaine for Post-Herpetic Neuralgia 2ELADUR(TM) Development Update: DURECT Receives Orphan Drug Designation for Bupivacaine for Post-Herpetic Neuralgia 3
(Date:11/24/2009)...versity School of Medicine (BUSM) and the Boston U...dentified a number of proteins whose activation al... cells with almost 97 percent accuracy. In additio...tional strategy to analyze this data and specifica...rcuits) that are active in cancer and "dormant" in...
(Date:11/24/2009)...ire-USNewswire/--Parties,familydinners,andothergat...r.Butthemerrimentcanchangetomiseryiffoodmakesyouor...-bin/prnh/20090824/FDALOGO ) ,, Typicalsymptoms...symptoms,whichcanstartanywherefromhourstodaysafter...dnewsisthatpracticingfourbasicfoodsafetymeasuresca...
(Date:11/24/2009)...syear-endapproaches,manyemployeesarefacedwithanarr...outakeadvantageofthesespecialtax-savingopportuniti...s,highlightsthefollowingkeyyear-endplanningconside...gaccounts(HealthFSAs) . Manyemployeestakeadvanta...ntheiremployer,shealthFSA.Theseemployeessavetaxesb...
(Date:11/24/2009)...StateFraternalOrderofPolicedistributedturkeys,cann...k ,, PORTJERVIS,N.Y.,Nov.24/PRNewswire-USNewswi...rtnershipwiththeNewYorkStateFraternalOrderofPolice...ewYork,sChildDevelopmentCenter,ProjectDiscoveryinP...toreceivefreeturkeys,ham,chickenandothertrimmingst...
(Date:11/24/2009)... cause of inflammatory bowel disease is largely un...ing 2009 Advances in Inflammatory Bowel Diseases, ... Clinical & Research Conference, December 3-6 ...ve mutation for Crohn’s disease. , ...2009 -- The molecular cause of inflammatory bowel ...
Breaking Medicine News(10 mins):Health News:Researchers identify proteins in lung cancer cells that may provide potential drug targets 2Health News:FDA Consumer Health Information: Food Safety Tips for Healthy Holidays 2Health News:The Right Tax Moves for Employees to Make Before Year-End 2Health News:The Right Tax Moves for Employees to Make Before Year-End 3Health News:Fraternal Order of Police Provides Food and Hope for Families in Port Jervis this Thanksgiving 2Health News:Researchers Identify Possible Causative Mutation for Crohn's Disease: Crohn's & Colitis Foundation Annual Conference to Present Emerging Research 2Health News:Researchers Identify Possible Causative Mutation for Crohn's Disease: Crohn's & Colitis Foundation Annual Conference to Present Emerging Research 3Health News:Researchers Identify Possible Causative Mutation for Crohn's Disease: Crohn's & Colitis Foundation Annual Conference to Present Emerging Research 4
...ation of Endocrine and Thyroid Surgeons (BAETS, pr...eons) is pleased to announce the publication of th...published by Dendrite Clinical Systems. This lates... of the report to record the current status of end...
...ests for Proposals; Lauds New Labor Agreement, HA...nt with union leaders, Department of Public Welfar... department is withdrawing its,request for proposa...and management representatives, we have reached an...
...(R) Swabs Warns Parents After Survey Finds Contami...CK, Mass., March. 21 The makers of LeadCheck(R),S...ay warned parents to,examine their children,s East...ores contained dangerous levels of the toxic,eleme...
...ns TODAY - Major Events at Summit, CPM...me 4,000 registered nurses,at eight Bay Area facil...alth today over serious problems with patient care...t line through,Sunday, March 30. A full schedule i...
...0, 2008)Documenting a twofold to fivefold increase...stent sleeplessness, public health researchers at ...ouston say they have completed the first prospecti...toms of insomnia and almost half of these youngste...
... to better understanding of the incurable neurolog...Day News) -- Mutations in a gene called GIGYF2 may...n,s disease in families with a history of the neur...sibly even preventive -- strategies that target th...
Other Medicine News:Health News:The Second National Audit Report of the BAETS 2Health News:The Second National Audit Report of the BAETS 3Health News:The Second National Audit Report of the BAETS 4Health News:The Second National Audit Report of the BAETS 5Health News:The Second National Audit Report of the BAETS 6Health News:PA Department of Public Welfare Cancels Plan to Privatize State Hospital Forensic Services 2Health News:4,000 RNs at 8 Sutter Hospitals to Strike Over Patient Care Problems 2Health News:4,000 RNs at 8 Sutter Hospitals to Strike Over Patient Care Problems 3Health News:Adolescents with chronic insomnia report 'twofold to fivefold' increase in personal problems 2Health News:Gene Linked to Form of Parkinson's Disease 2
...nal reference laboratory and a worldwide leader in...RUP offers an extensive test menu of highly comple...c pathology. Owned by the University of Utah, ARUP...he nation's university teaching hospitals and chil...
...nal reference laboratory and a worldwide leader in...RUP offers an extensive test menu of highly comple...c pathology. Owned by the University of Utah, ARUP...he nation's university teaching hospitals and chil...
...nal reference laboratory and a worldwide leader in...RUP offers an extensive test menu of highly comple...c pathology. Owned by the University of Utah, ARUP...he nation's university teaching hospitals and chil...
...nal reference laboratory and a worldwide leader in...RUP offers an extensive test menu of highly comple...c pathology. Owned by the University of Utah, ARUP...he nation's university teaching hospitals and chil...
Medicine Products: