Navigation Links
OSI Pharmaceuticals Announces Pivotal Phase III Tarceva Study,Published in the Journal of Clinical Oncology Showed Survival,Improvement in Patients with Pancreatic Cancer

Safety Profile

There have been infrequent reports of serious Interstitial Lung Disease (ILD)-like events, including fatalities, in patients receiving Tarceva for treatment of NSCLC, pancreatic cancer, or other advanced solid tumors. In the pancreatic cancer trial, other serious adverse events associated with Tarceva, and which may have included fatalities, were myocardial infarction/ischemia, cerebrovascular accident, and microangiopathic hemolytic anemia with thrombocytopenia. The most common side effects in patients with pancreatic cancer receiving Tarceva (100 mg) plus gemcitabine were fatigue, rash, nausea, anorexia, and diarrhea. Severe rash (5%) and severe diarrhea (5%) each resulted in dose reductions in 2% of patients, and discontinuation in up to 1% of patients. The most common side effects in patients with NSCLC receiving Tarceva monotherapy (150 mg) were mild to moderate rash (9%) and diarrhea (6%) which resulted in 1% of Tarceva-treated patients discontinuing therapy. When receiving Tarceva therapy, women should be advised against becoming pregnant or breastfeeding.

About OSI Pharmaceuticals

OSI Pharmaceuticals is committed to "shaping medicine and changing lives" by discovering, developing and commercializing high-quality and novel pharmaceutical products designed to extend life and/or improve the quality of life for patients with cancer and diabetes/obesity. The Company's oncology programs are focused on developing molecular targeted therapies designed to change the paradigm of cancer care. OSI's diabetes/obesity efforts are committed to the generation of novel, targeted therapies for the treatment of type 2 diabetes and obesity. OSI's flagship product, Tarceva(R) (erlotinib), is the first drug discovered and developed by OSI to obtain FDA approval and the only EGFR inhibitor to have demonstrated the ability to improve survival in both non-small cell lung cancer and pancreatic cancer patients in certain settings. OSI markets Tarcev
'"/>




Page: 1 2 3 4

Related medicine technology :

1. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
2. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
3. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
4. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
5. Sunesis Pharmaceuticals to Present at the C. E. Unterberg, Towbin Emerging Growth Conference
6. EPIX Pharmaceuticals to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
7. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
8. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
9. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
10. Cyclacel Pharmaceuticals Announces Results of Phase II Seliciclib Combination Studies
11. Arisaph Pharmaceuticals Announces Results of its Potent Smart DPP-4 Inhibitor, ARI-2243, at the ADA
Post Your Comments:
(Date:8/20/2014)... Calif. , Aug. 20, 2014 ... will be using advanced, ventilator technology from Covidien ... to care for patients. The ... more naturally, compared to conventional mechanical ventilation, and ... soon as possible. Patients on mechanical ventilation are ...
(Date:8/20/2014)... Aug. 20, 2014 Children aren,t the ... vaccinations to help prevent disease. The Centers for ... all adults, but currently, many adults are not ... National Immunization Awareness Month, and the American Lung ... especially those with lung disease, to talk with ...
(Date:8/20/2014)... -- Research and Markets  has announced the addition of ... their offering. Global Market Report of Pralmorelin ... and regionally ( Europe , Asia ... Latin America etc.). It captures Pralmorelin market trends, ... on three primary areas; manufacture methods & technology development, market ...
Breaking Medicine Technology:Torrance Memorial Medical Center Acquires Advanced Ventilator Technology to Enhance Patient Care 2American Lung Association Urges Adults with Lung Disease to Consult their Health Care Provider to Stay Current on Vaccinations 2American Lung Association Urges Adults with Lung Disease to Consult their Health Care Provider to Stay Current on Vaccinations 3Global Market Report of Pralmorelin 2
(Date:8/20/2014)... HealthDay Reporter WEDNESDAY, Aug. 20, 2014 ... group of rhesus monkeys from deadly Marburg virus, a very ... percent of those it infects, researchers report. The drug ... even when it was given three days after infection, according ... Science Translational Medicine . This is the first drug ...
(Date:8/20/2014)... the immune system is defective in people suffering from irritable ... ongoing issues with pain. , The research the first ... to explain why some painkillers may not offer satisfactory relief ... 10% of the community. There are different forms of ... often has the greatest impact on sufferers, quality of life. ...
(Date:8/20/2014)... Hundreds of Mirena IUD lawsuits ( http://www.themirenalawsuitcenter.com/ ... allegedly injured due to spontaneous migration of the IUD ... Superior Court, Bernstein Liebhard LLP reports. According to a ... Court has established procedures regarding the production of sales ... of the proceeding’s initial disposition pool. (In Re: Mirena ...
(Date:8/20/2014)... -- Loss of brain cells that act as a ... trouble falling and staying asleep, a new study suggests. ... severe and often results in nighttime confusion and wandering, ... from the Rush Memory and Aging Project, which includes ... are being followed until death, at which point their ...
(Date:8/20/2014)... HealthDay Reporter WEDNESDAY, Aug. 20, ... long been an option, but a new study shows that ... most common reasons women didn,t undergo reconstruction was that they ... or they were focused on their cancer treatment," said lead ... Sloan Kettering Cancer Center, in New York City. Also ...
Breaking Medicine News(10 mins):Health News:Drug for Ebola-Like Virus Shows Promise in Monkeys 2Health News:Drug for Ebola-Like Virus Shows Promise in Monkeys 3Health News:Pain treatments less effective for those with irritable bowel 2Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 2Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 3Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 4Health News:Seniors' Sleep Woes May Be Linked to Loss of Brain Cells 2Health News:Many Women Who Have Mastectomy Don't Get Breast Reconstruction: Study 2Health News:Many Women Who Have Mastectomy Don't Get Breast Reconstruction: Study 3
... for consolidating memories, researchers find , THURSDAY, Nov. 19 ... enhance associated memories upon waking, new research finds. , ... spatial memory, researchers at Northwestern University in Chicago showed ... played corresponding sounds, like a cat meowing and a ...
... A pediatric immunologist at The Children,s Hospital of ... the American Philosophical Society, an organization founded in ... Ph.D., received the Society,s Judson Daland Prize on ... treatment of inherited immune deficiency diseases. The ...
... ... Detective v3.0, with new enterprise-ready features and scalability , ... (PRWEB) November 19, 2009 -- Key Metric Software ... management software., , ,Duplicate File Detective v3.0 provides a number of new features ...
... Nov. 19 The gift of wings is the gift of ... US Airways is raising the bar for giving miles of hope. ... Mercy Medical Airlift and awarded hundreds of thousands of dollars in ... needing to travel for distant, specialized treatment. But through its Dividend ...
... (Tech) Vin Virtanen has developed a method for analysing ... connection and a wireless microphone. The objective was to ... to monitor snoring. By utilizing this technology, researchers from ... have investigated sleep disorders and further refined related screening ...
... , ... Services, known as one of the largest independent sales organizations for diagnostic imaging equipment, ... Nationwide Imaging Services a total turnkey solution for the medical imaging equipment industry. ... Brick, NJ (PRWEB) ...
Cached Medicine News:Health News:Sounds May Help Solidify Memories While Asleep 2Health News:Immunology expert at Children's Hospital receives APS prize for patient-oriented research 2Health News:Duplicate File Detective v3.0 Provides Enterprise-Grade Duplicate File Management 2Health News:US Airways to Match Miles with Mercy Medical Airlift 2Health News:A mobile phone or an MP3 player tells if you're sleeping soundly 2Health News:A mobile phone or an MP3 player tells if you're sleeping soundly 3Health News:Nationwide Imaging Services, Inc., Leader In Diagnostic Imaging Equipment, Announces The Creation Of New Business Division Nationwide Medical Equipment Services 2Health News:Nationwide Imaging Services, Inc., Leader In Diagnostic Imaging Equipment, Announces The Creation Of New Business Division Nationwide Medical Equipment Services 3
Compact format, fiber optic illumination for uniform reflection-free light. Polycarbonate housing with chrome-plated cone....
Sleek, all-metal head with large-diameter viewing window. 3X magnification....
Provides bright output and rotating lens with ultra-seal for pneumatic otoscopy....
... comes to laser treatment of AMD ... nothing compares to the Opal Photoactivator ... Visudyne (verteporfin for injection) therapy, the ... on any other laserfeatures,that ensure the ...
Medicine Products: