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Nymox Announces Positive Results from Newly Completed Long-term,Study of NX-1207 for Benign Prostatic Hyperplasia

HASBROUCK HEIGHTS, N.J.--(BUSINESS WIRE)--Mar 19, 2007 - Nymox Pharmaceutical Corporation (NASDAQ: NYMX) today announced positive results from its newly completed long-term outcome study of NX-1207 for benign prostatic hyperplasia (BPH). 26 clinical trial sites across the U.S. and 116 unselected subjects participated in the blinded, placebo controlled study.

The study assessed symptom scores and treatment outcome 8-19 months after NX-1207 treatment. Overall, without further NX-1207 treatment, patients initially treated with NX-1207 showed a total pooled mean improvement of 7.4 points in the primary outcome endpoint of AUA Symptom Score values, which reached statistical significance when compared with the placebo control (p=.028).

In terms of treatment outcomes, patients treated with NX-1207 had statistically significantly more (p=.02) favorable outcomes compared to placebo.

There have been no significant sexual side effects from NX-1207.

Paul Averback MD, CEO of Nymox said, "Nymox is continuing to carefully move this drug ahead as rapidly as possible. This placebo-controlled blinded clinical study demonstrates a striking degree of long-term improvement in BPH patients given NX-1207, and confirms the promising results from the earlier completed U.S. clinical trials."

Dr. Averback added, "The durability of BPH symptom improvement from NX-1207 treatment is clearly shown by this new data, which is of special interest to potential marketing partners for NX-1207."

The Company previously completed three U.S. trials for NX-1207, including most recently a Phase 2 double-blind, placebo controlled, randomized multi-site U.S. study, which showed positive efficacy and safety results for NX-1207 after 3 months in patients with BPH. Overall, patients treated with NX-1207 showed after 3 months a mean improvement of 9.35 points in AUA Symptom Score values, the standard scale used to evaluate B
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