Navigation Links
NuPathe Reports Positive Phase One Results for NP101 Transdermal,Therapy for Acute Migraine

CONSHOHOCKEN, Pa.--(BUSINESS WIRE)--Jun 8, 2007 - NuPathe Inc., a privately held specialty pharmaceutical company, today announced positive results from an initial Phase I study of NP101 SmartRelief, a novel treatment for acute migraine being developed by NuPathe.

NP101 combines NuPathe's SmartRelief(TM) proprietary iontophoretic transdermal technology with sumatriptan, the most widely prescribed treatment for acute migraine in the United States. Sumatriptan is also the active ingredient in IMITREX(R), which is also indicated for the treatment of acute migraine.

The study was a randomized, single-center, single-dose, six-period pilot study to evaluate four SmartRelief(TM) prototypes. The study compared sumatriptan pharmacokinetics and safety following administration of NP101 SmartRelief(TM) prototype patches, IMITREX 50 mg tablets, and IMITREX 6 mg subcutaneous injection. Results of the Phase I study were presented today in a poster presentation at the American Headache Society meeting in Chicago.

In the study, NP101 maintained continual therapeutic dosing levels of sumatriptan an average of four times longer than treatment with the 6 mg injection of IMITREX and up to twice as long as treatment with the 50 mg tablet of IMITREX. NP101 was also generally well tolerated.

"These results demonstrate that NuPathe's transdermal technology can deliver therapeutic drug levels quickly and then maintain those levels over a sustained period of time, which may significantly improve consistency of response and decrease frequency of recurrent migraines in patients," said Steven J. Siegel, MD, PhD, assistant professor, University of Pennsylvania, who presented the results in Chicago. "This controlled delivery option could represent an important alternative for patients who experience gastrointestinal disorders such as nausea and vomiting during their migraine attack."

According to Jane Hollingsworth
'"/>




Page: 1 2 3

Related medicine technology :

1. Corgenix Reports New Clinical Data Correlating AtherOx Technology With Vascular Disease
2. Cobalis Reports Phase III Trial Results for PreHistin in Seasonal Allergic Rhinitis
3. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
4. Cytos Biotechnology Reports Results from Phase IIa Study with CYT003-QbG10 in Patients Suffering from Atopic Dermatitis
5. Cytokinetics Reports Additional Clinical Trials Data for Ispinesib
6. The European Myeloma Platform Reports New Survival data for Revlimid Presented at the International Myeloma Workshop in Greece
7. Cytochroma Reports Positive Phase I Clinical Data for CTA018 Injection
8. Speedel Reports Successful SPP635 Phase IIa Trial in Hypertension
9. Columbia Laboratories Reports Positive Results from Multi-dose Pharmacokinetic Study of Vaginally-administered Lidocaine
10. CytRx Reports Promising Data from Its Open-Label Extension Clinical Trial of Arimoclomol in ALS
11. Affymax Reports Phase 2 Clinical Dose Ranging Results of Once-Per-Month Hematide for the Treatment of Anemia
Post Your Comments:
(Date:8/19/2014)... , Aug. 19, 2014  As power ... the country, Bernstein Liebhard LLP notes that women ... choose between a number of options that do ... surgical instrument. According to a report published by ... , these options include a mini-laparotomy and vaginal ...
(Date:8/19/2014)... 19, 2014 Research and Markets has ... of Material, by Technology, by Application & by Region- Global ... The demand for membranes is estimated to ... market to $29.31 billion Membrane technology was first ... as water filtration and kidney dialysis. In modern times, membranes ...
(Date:8/19/2014)... Avizia, Inc., a leading provider of cutting-edge ... equity financing round led by NextGen Angels along with ... will be used to continue to fuel the rapidly ... Edward Kennedy , CEO and president of Tollgrade ... Leonard Kurtzman , CFO of newBrandAnalytics, who joined the ...
Breaking Medicine Technology:As Morcellator Lawsuits Mount, Bernstein Liebhard LLP Notes Report Detailing Alternatives to Uterine Morcellation 2As Morcellator Lawsuits Mount, Bernstein Liebhard LLP Notes Report Detailing Alternatives to Uterine Morcellation 3Global Membranes (MF, RO, UF, Gas Separation, Dialysis, NF) Market - Forecasts to 2019 2Avizia Closes Funding Round 2
... Tarsa Therapeutics today announced that the Phase III ORACAL ... treatment of postmenopausal osteoporosis was successfully concluded and yielded ... used to support a New Drug Application (NDA) submission ... the fourth quarter of 2011, based on the study ...
... YORK, March 24, 2011 Reportlinker.com announces that ... its catalogue: RNAi Drug ... http://www.reportlinker.com/p0461653/RNAi-Drug-Delivery-Technologies-and-Global-Markets.html THIS ... to how the RNAi (ribonucleic acid interference) technologies market ...
Cached Medicine Technology:Tarsa Therapeutics Reports Positive Top-Line Results From Pivotal Phase III ORACAL Trial of its Oral Calcitonin in Treatment of Postmenopausal Osteoporosis 2Tarsa Therapeutics Reports Positive Top-Line Results From Pivotal Phase III ORACAL Trial of its Oral Calcitonin in Treatment of Postmenopausal Osteoporosis 3Tarsa Therapeutics Reports Positive Top-Line Results From Pivotal Phase III ORACAL Trial of its Oral Calcitonin in Treatment of Postmenopausal Osteoporosis 4Reportlinker Adds RNAi Drug Delivery: Technologies and Global Markets 2Reportlinker Adds RNAi Drug Delivery: Technologies and Global Markets 3Reportlinker Adds RNAi Drug Delivery: Technologies and Global Markets 4Reportlinker Adds RNAi Drug Delivery: Technologies and Global Markets 5Reportlinker Adds RNAi Drug Delivery: Technologies and Global Markets 6Reportlinker Adds RNAi Drug Delivery: Technologies and Global Markets 7Reportlinker Adds RNAi Drug Delivery: Technologies and Global Markets 8Reportlinker Adds RNAi Drug Delivery: Technologies and Global Markets 9Reportlinker Adds RNAi Drug Delivery: Technologies and Global Markets 10Reportlinker Adds RNAi Drug Delivery: Technologies and Global Markets 11Reportlinker Adds RNAi Drug Delivery: Technologies and Global Markets 12Reportlinker Adds RNAi Drug Delivery: Technologies and Global Markets 13Reportlinker Adds RNAi Drug Delivery: Technologies and Global Markets 14
(Date:8/19/2014)... week,s JAMA highlights the importance of physicians ... to treat patients. Written by Robert Vinci, MD, chief ... pediatrics at Boston University School of Medicine and Howard ... examines results of a study published in the same ... doctors can often over-emphasize certain types of data. , ...
(Date:8/19/2014)... multitasking and ways to train it have been identified ... de griatrie de Montral and the University of Montreal. ... effectiveness of this training. Cooking while having a conversation, ... while listening to a radio show multitasking ... it decreases with age, which makes it harder for ...
(Date:8/19/2014)... August 19, 2014 Kars4Kids , ... programs, announced today its partnership with New York State ... students in the Bronx. The giveaway will take place ... in Crotona Park on August 22. , “With ... we believe properly preparing children for school with the ...
(Date:8/19/2014)... 20, 2014 Top10BestSEOHosting.com has recently ... are the recommended suppliers for the webmasters who ... products. , According to the senior spokesman for ... most affordable hosting products on the market and ... a variety of online deals when service plans ...
(Date:8/19/2014)... “ Inbox Blueprint 2.0 ” from ... provide users with the tools necessary to build and ... strategies. The course which was originally launched in ... the internet marketing world. The commotion surrounding the products ... prompting an updated review of the course material. ...
Breaking Medicine News(10 mins):Health News:Review of clinical treatment of bronchiolitis in infants reveals over-reliance on one test 2Health News:Targeted brain training may help you multitask better 2Health News:Backpack Giveaway Kars4Kids Partners with New York State Senator Gustavo Rivera to Prepare Bronx Students for New School Year 2Health News:Fatcow Awarded As One of the Best Web Hosting Suppliers at Top10bestseohosting.com 2Health News:Anik Singal’s “Inbox Blueprint” Review Released By HonestyFirstReviews.com 2
... its expertise in serving 60 million Americans, OptumHealth developed myOptumHealth.com ... free access to clinically reviewed, easy-to-understand and actionable content, tools ... ... MN (PRWeb) December 3, 2008 -- OptumHealth Inc. , ...
... Mutual Community employees and their family and friends put their feet where ... to raise funds for charity in the inaugural HBA Great Australian Run. ... ... MBF and Mutual Community employees and their family and friends put their ...
... a nationally accredited provider of psychology, counseling ... 1992, has launched its long-awaited new website ... complete CE courses online on a seamless ... most states are required to maintain their ...
... invasive, image-guided treatment is a safe and precise method ... according to the first report on "self-embedding disorder," or ... findings will be presented today at the annual meeting ... "Radiologists are in a unique position to be the ...
... have determined that the circuitry in the area of ... patients suffering from stress-related psychiatric disorders. Results of the ... of the Radiological Society of North America (RSNA). ... disorders, traumatic memories are a source of anxiety," said ...
... Minimally invasive, image-,guided treatment is a safe and ... body, according to the first report on "self-,embedding disorder," ... findings will be presented today at the annual meeting ... "Radiologists are in a ...
Cached Medicine News:Health News:OptumHealth Launches myOptumHealth.com, Consumer-Focused Health and Wellness Information Web Site 2Health News:OptumHealth Launches myOptumHealth.com, Consumer-Focused Health and Wellness Information Web Site 3Health News:HBA People Walk the Talk for Better Health in the HBA Great Australian Run 2Health News:Revolutionary New Learning Website Makes Continuing Education a Pleasure 2Health News:Revolutionary New Learning Website Makes Continuing Education a Pleasure 3Health News:Revolutionary New Learning Website Makes Continuing Education a Pleasure 4Health News:Radiologists diagnose and treat self-embedding disorder in teens 2Health News:Stress-related disorders affect brain’s processing of memory 2Health News:Radiologists Diagnose and Treat Self-Embedding Disorder in Teens 2Health News:Radiologists Diagnose and Treat Self-Embedding Disorder in Teens 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: