Navigation Links
Novavax Vaccine Provides Robust Immune Response, Pre-Clinical Data,Show

Study Published in Vaccine Shows Strong Immune Response, Protection Against H9N2 Influenza Strain

ROCKVILLE, Md., April 02, 2007 /PRNewswire-FirstCall/ -- Novavax Inc.'s virus- like particle (VLP) vaccine triggered a robust immune response and provided protection against the H9N2 strain of avian influenza, according to pre- clinical data published in the online edition of the journal Vaccine.

Novavax's vaccine was tested in three animal models, including the ferret, which is the most predictive model for influenza vaccine effectiveness in humans. Ferrets experience flu symptoms very similar to people who are infected with the virus. Protection, as measured by a reduction in viral load, was assessed in vaccinated ferrets challenged with live H9N2 avian influenza. Like the H5N1 strain, the H9N2 strain initially spread among domestic poultry in Asia. Since then, it has been isolated from humans and is identified as having pandemic potential.

"This is the first time Novavax has measured the efficacy of our VLP vaccine against a live virus challenge in the very important ferret model," said Dr. Rick Bright, vice president of global influenza programs at Novavax. The Company previously conducted live virus challenge studies with the H5N1 strain in mice. "These data are very encouraging because the ferret is a more predictive model for efficacy in humans."

Virus-like particles mimic the three-dimensional structure of a virus but do not contain genetic material, so they cannot replicate or cause infection. As VLPs maintain functional properties of both influenza surface proteins (hemagglutinin and neuraminidase), they likely trigger multiple arms of the immune system to generate a broadly protective immune response.

Novavax has conducted several pre-clinical studies evaluating a number of its VLP vaccines against different strains of avian influenza. "All of the data we've accumulated to dat
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Novavax Pandemic Flu Vaccine Provided Protection Against a Lethal Challenge of Live Virus, Pre-Clinical Data Show
2. Novavax Reports Positive Pre-Clinical Study Results from Live Virus Challenge to Pandemic Flu Vaccine
3. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
4. DOR BioPharma Announces Issuance of European Patent for Its Oral Multivalent Botulinum Toxin Vaccine BT-VACC
5. From Clinical Cancer Research: Rethinking Therapeutic Cancer Vaccine Trials
6. DOR BioPharma Announces Publication Describing Results of Its Multivalent Botulinum Toxin Vaccine BT-VACC
7. Vaccine Can Prevent Cervical Cancer and Precancerous Lesions
8. Largest Cervical Cancer Vaccine Efficacy Trial Shows Cervarix Provides Excellent Protection Against Lesions Caused by Most Common Cancer-Causing Virus Types
9. Based on Up to 6 Years of Follow-Up, Biovest Announces Favorable Interim Blinded Data for Fast-Tracked Pivotal Phase 3 Clinical Trial of BiovaxID Anti-Cancer Vaccine for Non-Hodgkins Lymphoma
10. HepaLifes PBS-1 Cells for Influenza Vaccine Production Prove Superior at International Conference
11. New Flu Vaccine from PepTcell Could Provide Immunity Against All Strains of Influenza Virus
Post Your Comments:
(Date:1/15/2014)... Sono-Tek Corporation (OTC BB: SOTK) today announced sales of  ... to sales of $2,202,000 for the prior year period, an ... also shown growth over the preceding quarter,s sales, continuing a ... year. Markets that experienced sales increases over the prior year ...
(Date:1/15/2014)... 2014 As health officials across the Midwest warn against ... in Michigan will offer free diagnostic ... Meijer pharmacists to administer tests and, in some cases, fill ... participating in the study. The Grand ...
(Date:1/15/2014)... , Jan. 15, 2014 Massachusetts General Hospital ... AMGN ) announced today that they have ... validate new therapeutic targets and develop novel therapies ... that affects millions worldwide. The MGH-Broad-Amgen collaboration brings ...
Breaking Medicine Technology:Sono-Tek Announces Third Quarter Results 2Sono-Tek Announces Third Quarter Results 3Sono-Tek Announces Third Quarter Results 4Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4
(Date:7/11/2014)... July 11, 2014 As reported by ... For Cocaine: Are Genetics To Blame (6/30), Indino Downey ... cocaine and paraphernalia to smoke it with. His father, ... that his son inherited from him may have something ... made the news during the 1980s and 1990s for ...
(Date:7/11/2014)... Los Angeles, CA (PRWEB) July 11, 2014 ... Kevin Sands today announces that he uses mini and ... these treatments offer the defining feature that distinguishes dental ... of teeth in addition to the crowns. This alone ... dental implants also offer advantages related to comfort, ...
(Date:7/11/2014)... FRIDAY, July 11, 2014 (HealthDay News) -- Polio is ... in places like Afghanistan, Nigeria and Pakistan. Giving vaccinated ... boost their immunity and help eradicate the highly infectious ... vaccine is highly effective, immunity wanes as early as ... still be infected and contribute to the spread of ...
(Date:7/11/2014)... For breast cancer patients, the era of personalized medicine ... advances by USC Stem Cell researcher Min Yu and ... , In a July 11 study in Science ... breast cancer cells circulating through the blood streams of ... the "seeds" of metastasis, which travel to and establish ...
(Date:7/11/2014)... Jupiter, FL (PRWEB) July 11, 2014 ... airing on RFD-TV, next Tuesday, July 15, 2014, at ... explores Sunbelt's line of proprietary products, which are designed ... agricultural crops. Audiences will learn how these products help ... the environment in which it is grown. , The ...
Breaking Medicine News(10 mins):Health News:Roberty Downey's Son Arrested For Cocaine 2Health News:Dental Implant Dentist, Kevin Sands DDS, Now Uses Mini and Full Mouth Implants to Replace Missing Teeth 2Health News:Researchers Assess New Way to Boost Polio Immunity 2Health News:New Episode of American Farmer Featuring Sunbelt, UniSouth Genetics, and Michigan Milk Producers Association Airing on RFD-TV 2
... The upcoming 25th Anniversary EAU Congress in Barcelona from April ... biggest meetings in recent years with around 12,044 participants already ... one of the biggest international urology meetings in the world ... of the most highly attended and, perhaps, the most extensive ...
... ... fueled by latest release of enterprise business performance management solution , ... Natick, MA (PRWEB) April 9, 2010 ... reporting solutions for small to mid-sized companies today announced an extraordinary 51% increase ...
... at 3 linked to behavior changes at age 5, ... children when they,re 3 seems to lead to more ... into account the child,s initial level of aggression. ... to backfire, new research suggests. , "We all ...
... ... super charged positive attitude? Well now many can download JNL,s iPhone application onto one of ... production for the past few month, making sure that her iPhone went above and beyond ... ...
... ... health care than other nations. Low back pain is the number two most common reason ... other spinal issues will now be able to see, touch and thereby better understand common ... Issaquah, ...
... finds that Hispanics live in areas with more ... cancer screening. Published early online in CANCER ... Society, the study indicates that differences in areas, ... Hispanics are less likely to undergo colorectal cancer ...
Cached Medicine News:Health News:Anniversary EAU Congress in Barcelona tops attendance registrations 2Health News:Centage Corporation Reports 51% Growth in Revenue for Q1 over Same Period as Last Year 2Health News:Centage Corporation Reports 51% Growth in Revenue for Q1 over Same Period as Last Year 3Health News:Spanking May Make a Child More Aggressive 2Health News:Spanking May Make a Child More Aggressive 3Health News:International Fitness Bikini Model Turn Bega-Brand Mogul & Celebrity Jennifer Nicole Lee Launches the JNL iPhone App 2Health News:International Fitness Bikini Model Turn Bega-Brand Mogul & Celebrity Jennifer Nicole Lee Launches the JNL iPhone App 3Health News:International Fitness Bikini Model Turn Bega-Brand Mogul & Celebrity Jennifer Nicole Lee Launches the JNL iPhone App 4Health News:Latest Resource From Dynamic Disc Designs Helps Physicians Educate Patients 2Health News:Latest Resource From Dynamic Disc Designs Helps Physicians Educate Patients 3Health News:Hispanics live in areas with limited capacity for colorectal cancer screening 2
... is a semi-rigid system intended for ... Slim-LOC is based on the comprehensive, ... market technology. The Slim-LOC system offers ... Reduced width (16 mm), low profile ...
... Osmium is a cervical plate system ... spine. The implant provides for the ... the bone transplant has consolidated. Optimized ... and bicortical fixation. Maximum purchase also ...
... is designed to meet the clinical challenges ... attached locking mechanism and the choice of ... variable angle screws for ease of implantation ... plate system allows the surgeon the versatility ...
... system is the lowest profile plate clinically ... integrated lock mechanism, which is designed to ... appreciate the narrow width, which decreases the ... system also offers easy to use instrumentation ...
Medicine Products: