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Northfield Laboratories Reports Results of Pivotal Phase III Trauma,Study

k following traumatic injuries beginning in the prehospital setting. Treatment began at the scene of injury, continued in the ambulance during transport, and for up to 12 hours post-injury or a total of 6 units. Patients then received donated blood if they continued to bleed. Patients in the control group received the standard of care: saline in the field and during transport, followed by blood upon arrival at the hospital. Thirty-two Level I trauma centers participated in the study, which was conducted to seek an indication for the use of PolyHeme that addresses a critical, unmet medical need: the unavailability of blood.

In December 2006, Northfield announced that it had received the preliminary draft top-line data from its contract research organization. Northfield indicated that due to certain discrepancies in the data identified during its initial review, it became necessary to resolve the discrepancies and unlock the study database to make any necessary corrections. The process has now been completed, the study database relocked, and the data reanalyzed. Northfield has also had the opportunity to further analyze the study data, including additional safety data. These data have not been submitted to or reviewed by FDA.

About Northfield Laboratories

Northfield Laboratories, Inc., is a leader in developing an oxygen-carrying red blood cell substitute for the treatment of life-threatening blood loss, when an oxygen-carrying fluid is required and red blood cells are not available. PolyHeme(R) is a solution of chemically modified human hemoglobin that requires no cross matching and is, therefore, compatible with all blood types. It has a shelf life in excess of 12 months. For further information, visit www.northfieldlabs.com.

Forward Looking Statement

This press release may contain forward-looking statements concerning, among other things, Northfield's future business plans and strategies and clinical and regulatory developments af
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