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New Study Suggests Better Patient Outcomes with CYPHER,Sirolimus-Eluting Coronary Stent than with Taxus Stent in,Real-World Clinical Settings

n of TLR in small vessels (2.9 percent versus 4.8 percent in vessels less than 2.8 mm in diameter; p=0.046) compared to the Taxus Stent.

In the United States, the CYPHER(R) Stent is indicated for previously untreated lesions that are less than 30 mm in length with a reference vessel diameter ranging from more than 2.50 mm to less than 3.50 mm.

"Studies have shown that TLR is not benign. These registry findings provide additional assurance to the interventional cardiology community regarding the efficacy of the CYPHER(R) Stent to prevent the need for repeat revascularizations in a real-world clinical setting," said David E. Kandzari, M.D., F.A.C.C., F.S.C.A.I., Chief Medical Officer, Cordis Cardiology Division of Cordis Corporation.

About the CYPHER(R) Stent

The CYPHER(R) Stent has been chosen by cardiologists worldwide to treat approximately three million patients with coronary artery disease. The safety and efficacy of the device is supported by a robust clinical trial program that includes more than 70 studies that examine the performance of the CYPHER(R) Stent in a broad range of patients.

Developed and manufactured by Cordis Corporation, the CYPHER(R) Stent is currently available in more than 80 countries and has the broadest clinical experience and longest-term clinical follow-up of any drug-eluting stent. The next version of sirolimus-eluting stent, the CYPHER(R) SELECT(TM) Sirolimus- eluting Coronary Stent, was launched in Europe, Asia Pacific, Latin America and Canada in 2003. The CYPHER(R) SELECT(TM) Plus Stent, the third version of a sirolimus-eluting coronary stent, received CE Mark in 2006 and is currently available in many markets outside the United States.

For more complete information on indications, contraindications, warnings and precautions, see the Instructions for Use available at www.cypherstent.com.

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