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New Study Reveals Limitations of a Complex and Challenging Global,Tuberculosis Drug Marketplace

ately US$315 million per year, including high income country sales of the four first-line drugs commonly used to treat drug susceptible disease. Although researchers found that a number of factors limited the ability to estimate the global market for treatment for drug resistant disease, they were able to determine that US$54 million is spent annually on the more expensive, second-line treatments in the ten countries studied.

"Understanding how drugs actually reach patients is critical," said Nina Schwalbe, TB Alliance Director of Policy. "We know that desperately needed new cures that shorten and simplify TB treatment will only be effective if they are available to those who need them. This research offers valuable insights into what we at the TB Alliance and others will need to do to get new drug regimens to patients."

The TB Alliance is driving the advancement of the most comprehensive portfolio of TB drugs ever, and is accelerating discovery, preclinical and clinical research of known and novel classes of antibiotics to shorten and simplify TB treatment. The Alliance is committed to making all drugs developed by its research partnerships affordable, universally adopted, and available to all who need them.

The research for Pathway to Patients was conducted in partnership with IMS Health, Inc., a global strategic consulting group focused on the pharmaceutical and health care industries. The project was financed by a grant from the Netherlands Ministry of Foreign Affairs' Department of Development Cooperation (DGIS) and with the support of the Bill & Melinda Gates Foundation.

About TB Disease

Tuberculosis (TB), although curable, continues to kill someone somewhere in the world every 20 seconds -- about 4,400 people every day, or 1.6 million in 2005 alone, according to the latest estimates from the World Health Organization (WHO). TB is second only to HIV as the leading infectious killer of adults worldwide. It accounts for mor
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