New Quality Control Systems for Every Laboratory Application ( erum plasma urine and cerebrospinal ...)

New Quality Control Systems for Every Laboratory Application

erum, plasma, urine, and cerebrospinal fluid. For this one assay, three QC materials may therefore be required.

Packaging can also be a determining factor in the ideal QC material. How many assays a lab performs, and how much volume is used per assay, will dictate the volume of QC material the lab uses, and what size vial the user prefers. The ideal material will also be available at a reasonable cost, on an as-needed or standing order basis, and be backed up by good customer service and appropriate data analysis programs from the vendor.

Fortunately, new QC materials are keeping pace with the demands of laboratory customers. For specialty labs within clinical chemistry, QC materials containing a variety of immune, autoimmune, endocrine, lipid, and drug analytes are available. Serum, urine, and CSF controls are available for relevant clinical chemistries. Other materials are designed for QC in coagulation, hematology, infectious disease, or serology labs. These materials often are available in several sizes and packed as sets representing normal and abnormal analyte concentrations. Unopened vial shelf life may be years; open vial shelf life is often a week or more. For the lab requiring a unique analyte, an unusual combination of analytes, or a special matrix, vendors like Quantimetrix can design custom QC materials and maufacture them to order.

Vendors of these new materials also supply data management and customer support to provide laboratory customers with a wealth of useful information about their analytical performance. For example, Bio-Rad offers a program whereby customer's daily QC results can be transmitted electronically to their central data management system, and the QC report can be retrieved and reviewed within minutes. Assays can be monitored for linearity. QC results can be compared with those from other customers using similar methods and equipment. Multiple assays can be compared side by side to detect shifts due to instru
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