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New Position Statement from The North American Menopause Society,Addresses Use of Local Estrogen for Treatment of Vaginal Atrophy in,Postmenopausal Women

CLEVELAND--(BUSINESS WIRE)--May 10, 2007 - An evaluation of the safety and effectiveness of local vaginal estrogen therapy for the treatment of vaginal atrophy, a frequent complaint of postmenopausal women, has just been released by The North American Menopause Society (NAMS). Entitled "The role of local vaginal estrogen for treatment of vaginal atrophy in postmenopausal women: 2007 position statement of The North American Menopause Society," the document was developed by an Editorial Board of five clinicians and researchers expert in this area of women's health, then approved by the NAMS Board of Trustees.

"Although hot flashes typically accompany the loss of ovarian estrogen production at menopause, they usually abate over time regardless of whether estrogen therapy is used," said Gloria A. Bachmann, MD, Associate Dean for Women's Health, Professor of Obstetrics and Gynecology and Professor of Medicine, UMDNJ, Robert Wood Johnson Medical School, New Brunswick, NJ, and Chair of the Editorial Board. "In contrast, vaginal symptoms (eg, vaginal dryness, vulvovaginal irritation and itching, and painful intercourse) are usually progressive and unlikely to resolve spontaneously. Left untreated, vaginal atrophy can result in years of discomfort, with a significant impact on quality of life. An estimated 10% to 40% of postmenopausal women have symptoms related to vaginal atrophy, yet only about 25% of symptomatic women seek medical help."

The new position statement represents the most authoritative state-of-the-science summary. Significant findings include:

-- Estrogen therapy, used either locally (ie, vaginally) or systemically (eg, orally, through the skin), is considered the therapeutic standard for moderate to severe vaginal atrophy.

-- Local vaginal delivery of estrogen is available in North America in government-approved therapies via cream, tablet, and ring--with fewer systemic effects than
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