Navigation Links
New Phase 3 Study Published in The Lancet Evaluates Efficacy and,Safety of Prezista/Ritonavir vs. Kaletra as Part of HIV Combination,Therapy in Treatment-Experienced Adults With HIV

BRIDGEWATER, N.J., July 05, 2007 /PRNewswire/ -- Results from the primary analysis of a randomized, controlled, open-label, Phase 3 study showed that 77 percent of treatment-experienced HIV-1 infected adults taking PREZISTA(TM) (darunavir) 600 mg tablets with 100 mg ritonavir (PREZISTA/r) twice daily, plus an optimized background regimen (OBR) of antiretroviral (ARV) agents, reached a plasma viral load of <400 copies/mL at week 48, compared to 68 percent of patients taking Kaletra(R)1 (lopinavir/ritonavir) 400 mg/100 mg twice daily, plus OBR in a per-protocol analysis. The mean difference in response was nine percent and was statistically significant (95 percent confidence interval 2-16).

The 48-week efficacy and safety results, published in the July 7, 2007 issue of The Lancet, will also be presented at the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2007) in Sydney, Australia on July 24, 2007.

The Phase 3 study, known as TITAN, (TMC114/r In Treatment-experienced pAtients Naive to lopinavir/ritonavir), compared the efficacy and safety of PREZISTA/r with the protease inhibitor (PI) lopinavir/r in treatment- experienced adult patients who were lopinavir/r-naive. The primary endpoint of this study was non-inferiority (95 percent CI lower limit for the difference in treatment response -12 percent or greater) for HIV RNA of less than 400 copies per mL in plasma at week 48 (per-protocol analysis).

"This is exciting new information that adds to the body of knowledge on PREZISTA in a much broader group of treatment-experienced patients," said Daniel Berger, MD, medical director of NorthStar Healthcare and clinical assistant professor of medicine at the University of Illinois, Chicago.

The 48-week primary analysis from the TITAN study provides additional information regarding efficacy and safety of PREZISTA/r in combination with other ARV agen
'"/>




Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
2. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
3. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
4. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
5. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
6. Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis
7. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
8. NexMed Announces Completion of Patient Enrollment in Two Pivotal Phase 3 Studies for Anti-Fungal Product
9. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
10. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
11. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
Post Your Comments:
(Date:8/27/2015)... , Aug. 27, 2015  Eli Lilly and Company ... Global Healthcare Conference on Thursday, September 17, 2015. ... of Lilly Oncology and Richard Gaynor , M.D., ... for Lilly Oncology, will participate in a fireside chat ... A live audio webcast will be available on the ...
(Date:8/27/2015)... , Aug. 27, 2015   Women Grow , the fastest-growing ... is partnering with the Cannabis World Congress & Business ... to produce 15 business-focused educational sessions. CWCBExpo in LA will ... Angeles Convention Center in Los Angeles, ... the West Coast for the marijuana industry. The ...
(Date:8/27/2015)... Aug. 27, 2015  MiMedx Group, Inc. (NASDAQ: ... human amniotic tissue and patent-protected processes to develop ... Wound Care, Surgical, Orthopedic, Spine, Sports Medicine, Ophthalmic ... corrected the multiple inaccuracies in the press release ... the recent rulings from the Patent Trial and ...
Breaking Medicine Technology:Lilly to Participate in Morgan Stanley Global Healthcare Conference 2Cannabis World Congress in Los Angeles Boasts Women Grow Sponsored Education 2Cannabis World Congress in Los Angeles Boasts Women Grow Sponsored Education 3Cannabis World Congress in Los Angeles Boasts Women Grow Sponsored Education 4MiMedx Corrects Inaccuracies In MTF Press Release Regarding The Recent Rulings From The Patent Trial And Appeal Board 2MiMedx Corrects Inaccuracies In MTF Press Release Regarding The Recent Rulings From The Patent Trial And Appeal Board 3MiMedx Corrects Inaccuracies In MTF Press Release Regarding The Recent Rulings From The Patent Trial And Appeal Board 4
... 2011 Boston Scientific Corporation (NYSE: BSX ) ... to fund the "Donald S. Baim, M.D., ,75 Scholarship Fund" ... the late interventional cardiology pioneer and Yale School of Medicine ... Officer from 2006 until 2009, when he died unexpectedly. ...
... Calif., Feb. 15, 2011 Viral Genetics, Inc. (Pink Sheets: ... M. Karen Newell Rogers and Advisor Mr. Richard Gerstner will ... for Lyme, Inc. The award presentation is set for the ... Dr. Newell Rogers is being recognized for her research on ...
Cached Medicine Technology:Boston Scientific Establishes Endowment for Donald S. Baim, M.D., Scholarship at Yale School of Medicine 2Boston Scientific Establishes Endowment for Donald S. Baim, M.D., Scholarship at Yale School of Medicine 3Boston Scientific Establishes Endowment for Donald S. Baim, M.D., Scholarship at Yale School of Medicine 4Viral Genetics' Researcher and Advisor Set to Share Award 2Viral Genetics' Researcher and Advisor Set to Share Award 3
(Date:8/29/2015)... ... August 29, 2015 , ... People ... pulmonary disease (including emphysema), or asthma, are at higher risk from wildfire smoke ... attack, heart failure or heart-rhythm problems (arrhythmia or irregular heartbeat) are also sensitive ...
(Date:8/29/2015)... ... , ... The popular television program VOICES IN AMERICA, hosted by legendary star ... devoting an entire short segment to the subject of diabetes. Diabetes is a debilitating ... daily basis, but recent advancements in medical science may prove to be a significant ...
(Date:8/28/2015)... ... ... Rio Salado College joined nine educational institutions in Washington D.C., ... EDUCAUSE - Next Generation Learning Challenges 2015 Breakthrough Models Incubator funded by the ... Incubator hosted by EDUCAUSE and NGLC, which is designed to bring leadership teams ...
(Date:8/28/2015)... ... August 28, 2015 , ... An online provider of ... make the purchase of CPAP equipment more affordable by offering shipping at no cost ... of CPAP products and orders of any size. My Cpap Store is located in ...
(Date:8/28/2015)... ... August 28, 2015 , ... The Kentucky State Department of Workforce Investment Commissioner ... they are applying for, they are unable to pass the initial drug test and ... testing policies in order to be able to hire long-term, skilled talent. (1) Will ...
Breaking Medicine News(10 mins):Health News:Heart Fit Clinic Sounds the Alarm on Forest Fire Smoke and Chronic Heart Disease in Calgary Area 2Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 2Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 3Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 4Health News:My Cpap Store Now Offering Delivery Special 0 Cost to You 2Health News:Hiring Obstacles: Drug Abuse a Problem for Workforce 2Health News:Hiring Obstacles: Drug Abuse a Problem for Workforce 3Health News:Hiring Obstacles: Drug Abuse a Problem for Workforce 4
... It,s National Nutrition Month(R) and Cabot Creamery Cooperative ... Year-Round HealthCABOT, Vt., March 6 March is ... Dietetic Association,s campaign designed to focus attention on ... developing sound eating and physical activity habits, Cabot ...
... Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL ... vice president and chief financial officer, is scheduled ... Capital Healthcare Conference in Miami, Florida on Tuesday, ... http://www.newscom.com/cgi-bin/prnh/20030226/RIGLLOGO )To access the live audio webcast or ...
... by the U.S. Supreme Court will protect the rights of consumers who ... “The Supreme Court’s ruling this week is an important victory for plaintiffs ... Kientz. , ... Austin, TX (Vocus) March 6, 2009 -- A ruling ...
... direct-to-traveler oxygen services for airlines and individuals, today announced it is ... commercial flights originating or departing from a U.S. airport allow passengers ... aircraft. The U.S. Department of Transportation regulation (14 CFR 382 published ... , ...
... Wis., March 5 For Shannon Kenitz of Madison, Wisconsin, ... annual Road Warrior contest has meant hope for a ... the mother of a special needs child herself, and she,s ... bonus points and one million American Airlines AAdvantage miles to ...
... exercise equals that of stopping smoking, experts say, , , THURSDAY, ... they are 50 can extend their life span by more ... found that exercising has the same beneficial effect on length ... almost half of middle-age men don,t exercise, the researchers said. ...
Cached Medicine News:Health News:Photo: March Forth Into Spring with a Healthy Approach to Diet and Exercise 2Health News:Photo: March Forth Into Spring with a Healthy Approach to Diet and Exercise 3Health News:Photo: March Forth Into Spring with a Healthy Approach to Diet and Exercise 4Health News:Supreme Court Ruling is a Victory for Consumers Injured by Dangerous Drugs, Says Hissey Kientz, LLP 2Health News:Supreme Court Ruling is a Victory for Consumers Injured by Dangerous Drugs, Says Hissey Kientz, LLP 3Health News:OxygenToGo Is Poised To Help Airlines Struggling With New Portable Oxygen Concentrator Regulations From The U.S. DOT 2Health News:OxygenToGo Is Poised To Help Airlines Struggling With New Portable Oxygen Concentrator Regulations From The U.S. DOT 3Health News:Mother of Sick Child Donates Millions to Children 2Health News:Men Who Get Active in Midlife Live Longer 2Health News:Men Who Get Active in Midlife Live Longer 3
Convenience, Protection, Comfort and Security -- FirstChoice pouches are your product of choice if you are looking for the convenience of a one-piece pouch that is either cut-to-fit or pre-cut to you...
Inquire...
Superior comfort and flexibility are achieved through the revolutionary air pocket technology in the dimpled, ultra-thin SoftFlex skin barrier along with a discreet pouch shape and size....
Inquire...
Medicine Products: