Navigation Links
New Data on Genmab and GlaxoSmithKline's Ofatumumab: Phase II Study,in Rheumatoid Arthritis to be Presented at EULAR

COPENHAGEN, Denmark; April 25, 2007 - Genmab A/S (CSE: GEN) announced today that the results of a Phase II study with ofatumumab (HuMax-CD20™) in patients with rheumatoid arthritis (RA) have been accepted for oral presentation at the 2007 Annual European Congress of Rheumatology (EULAR). The oral presentation, which will include new results from the double-blind, placebo controlled Phase II study with ofatumumab, along with data from the previous interim analysis, will be described by Professor Mikkel Østergaard, Department of Rheumatology, Copenhagen University Hospital on June 16, 2007. The abstract for the presentation will be available at www.eular.org in mid-May.

Genmab A/S and GlaxoSmithKline have a worldwide agreement to co-develop and commercialize ofatumumab.


About the study

A total of 226 patients with active RA who have previously failed one or more disease-modifying anti-rheumatic drugs (DMARDs) were enrolled in the Phase II study. Patients were randomized to one of 4 treatment groups (300 mg, 700 mg or 1000 mg of ofatumumab or placebo). Patients were permitted to continue therapy with stable doses of methotrexate and low dose prednisolone. ACR and EULAR responses were assessed in the primary intention-to-treat efficacy population at 24 weeks.


'"/>




Page: 1

Related medicine technology :

1. GlaxoSmithKline and Genmab Present Positive Phase II Results With ofatumumab in Patients With Rheumatoid Arthritis (RA)
2. Genmabs HuMax-EGFr Shows Broad Potential in Cancer Treatment
3. Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
4. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
5. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
6. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
7. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
8. Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis
9. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
10. NexMed Announces Completion of Patient Enrollment in Two Pivotal Phase 3 Studies for Anti-Fungal Product
11. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
Post Your Comments:
(Date:8/20/2014)... NEW YORK , Aug. 20, 2014 ... market research report is available in its ... Insurance in Canada, Key Trends and Opportunities ... Synopsis The report ... insights into the Canadian personal accident and ...
(Date:8/20/2014)... The National Necrotizing Fasciitis Foundation (NNFF) today announced ... successfully treated for a life threatening form of necrotizing fasciitis, ... , Medical Director of Inpatient Wound Care and founder of ... Rancho Mirage, California . Dr. ... Crew at Seton Hospital in Daly City, ...
(Date:8/20/2014)... , Aug. 20, 2014   Ventana Medical ...  Group, today announced that its VENTANA System for ... in the European Union for routine pathology, including ... consisting of VENTANA Virtuoso software coupled with either ... HT slide scanner, provides automated digital slide creation, ...
Breaking Medicine Technology:Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 2Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 3Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 4Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 5Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 6Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 7Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 8Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 9Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 10Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 11Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 12Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 13Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 14Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 15Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 16Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 17Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 18Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 19Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 20Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 21Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 22Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 23Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 2Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 3Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 4Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 5Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 6Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 2Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 3
... Alere Health, LLC announced today that it has ... Health Information Products Certification for Health Information Line. ... a 24/7 nurseline staffed by highly experienced, registered ... decisions by providing immediate clinical support for everyday ...
... BOTHELL, Wash., April 6, 2011 BioLife Solutions, Inc. ... grade biopreservation media products for cells and tissues, today ... ended March 31, 2011. This represents 6% sequential growth ... growth from the first quarter of 2010.   ...
Cached Medicine Technology:Alere Earns NCQA Health Information Products Certification for Health Information Line 2BioLife Solutions Announces Record Quarterly Revenue 2BioLife Solutions Announces Record Quarterly Revenue 3BioLife Solutions Announces Record Quarterly Revenue 4
(Date:8/20/2014)... August 20, 2014 A new trend ... a medical exam before issuing an approximate quote for ... company is now helping the public to obtain life ... system at http://quotespros.com/life-insurance.html . , The coverage ... more regulations have appeared in many U.S. states. Some ...
(Date:8/20/2014)... -- A group representing U.S. obstetricians is calling for ... According to the American College of Obstetricians and Gynecologists ... the safety and effectiveness of flu vaccination during pregnancy. ... be particularly dangerous to pregnant women, as it can ... Riley, chair of the college,s Immunization Expert Work Group, ...
(Date:8/20/2014)... study in Australia examined patient and tumor characteristics ... of tumor cell growth) in an effort to ... patients. , Author: Sarah Shen, ... and colleagues. , Background: The tumor characteristic ... has been connected with prognosis and survival in ...
(Date:8/20/2014)... Aug. 20, 2014 -- An imaging study of ... found deficits in specific regions of brain white ... in CCS users. , Researchers used diffusuion ... with fractional anisotropy, to investigate the white matter ... in multiple regions of the brain, including the ...
(Date:8/20/2014)... 20, 2014 (HealthDay News) -- Pigs, hearts transplanted into ... twice as long as previously achieved, researchers report. ... to use animal organs to shorten transplant waiting lists. ... engineered piglets into baboons, abdomens. The genetic engineering and ... are what enabled the hearts to survive for more ...
Breaking Medicine News(10 mins):Health News:Life Insurance Quotes Without Medical Exams Now Displayed to Adults at Insurance Website 2Health News:All Pregnant Women Need Flu Shot: Ob/Gyn Group 2Health News:Patient, tumor characteristics for high-mitotic rate melanoma 2Health News:Pigs' Hearts Beat for a Year in Baboons' Abdomens 2
... US researchers have successfully cured advanced melanoma skin cancer ... them to attack the cancer cells. // ,A ... have confirmed in their research that are published in ... as the most deadly type of skin cancer can ...
... NHS Quality Improvement Scotland have expressed concern over the ... their pap smears done regularly.// They feel that health ... give out importance of smears in preventing cervical cancer. ... take part in this highly successful screening programme," a ...
... Council suggests that cancers like cervical cancers or womb ... hormone in semen.// The researchers said that high levels ... a report in the Journal of Endocrinology and Human ... should ask their sexual partners to use condoms. "Sexually ...
... Sciences Department conducted a study to examine how bacteria ... like Antarctica and hot springs.// The team led by ... made a difference in the ability of the bacteria ... heat. The study appears in the journal Nature. ,The ...
... a potential of growing by a whopping 25 percent ... year by 2012, Tourism Minister Ambika Soni said Wednesday.// ... at the response from foreign patients, we estimate that ... said Soni while releasing the "Incredible India: The Global ...
... place, and in itself, can make heaven of Hell, and ... Though delicate as the most exquisite silk ever woven it ... strongest forces in this universe. Yet when subject to strain ... unravels deep within and yet another perfect body crumbles before ...
Cached Medicine News:Health News:Gene Therapy Used In Treating Cancer 2Health News:Bacteria Can Survive In Extreme Heat 2Health News:Medical Tourism can Fetch Rs.100 bn Annually by 2012 2Health News:Medical Tourism can Fetch Rs.100 bn Annually by 2012 3Health News:Mind in a Bind – Alternative Intervention 2Health News:Mind in a Bind – Alternative Intervention 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: