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New Data Suggests Less Abuse-Related Effects For OROS,Methylphenidate

e ratio of abuse reports to prescribed use for OROS(R) methylphenidate (3.2 x 10-6) was lower than that of other methylphenidate formulations (12 x 10-6); similarly, this ratio was low for atomoxtine (3.5 x 10-6). Non-methylphenidate stimulants have the highest ratio of DAWN abuse reports to prescribed use (14 x 10-6) ; Ciccone, P.E., Starr, H.L., Coleman, J.J., Mrazik, T., DuPont, R.L., Bensinger P.B., ). APA Poster Board Number NR526: OROS MPH(R): A Methylphenidate Formulation with a Low Potential for Abuse, 2007.

(2) Kessler RC, Adler L, Barkley R, Biederman J, Conners CK, Demler O, Faraone SV, Greenhill LL, Howes MJ, Secnik K, Spencer T, Ustun TB, Walters EE, Zaslavsky AM. "The Prevalence and Correlates of Adult ADHD in the United States: Results from the National Comorbidity Survey Replication." American Journal of Psychiatry. 2006. Vol 163. Pg 724-732.

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