Navigation Links
New Data Shows Once a Day Lamictal XR is Effective in Treating,Patients with Partial Seizures

nal formulation demonstrated fewer daily fluctuations in serum concentration and more stable blood levels over time."

ABOUT THE ARMOR STUDY

In the ARMOR study, patients naive to Lamictal, thirteen years of age or older with uncontrolled partial seizures, taking a stable regimen of 1 or 2 AEDs were enrolled in an 8 week baseline phase. Patients having 8 or more partial seizures were randomized to receive either once daily Lamictal XR or placebo. The treatment period consisted of escalation (7 weeks) and maintenance phases (12 weeks) with dosing based on background AEDs. The primary endpoint was percentage change from baseline in weekly partial seizures during the entire treatment phase.

Of 326 patients enrolled, 236 were randomized and included in the intent- to-treat population (116 Lamictal XR, 120 placebo). The median percent decrease from baseline in all partial seizures was 46 percent compared to 24 percent for placebo during the entire treatment phase, 28 percent compared to 16 percent during the escalation phase of treatment and 58 percent compared to 27 percent during the maintenance phase of treatment.

Time to greater than or equal to 50 percent reduction in seizure frequency was analyzed using a two sided log-rank statistic. In patients taking Lamictal XR, 42 percent achieved greater than or equal to 50 percent reduction in seizure frequency at the end of the treatment period. The time to achieve and maintain greater than or equal to 50 percent reduction in seizure frequency with Lamictal XR was reached at day 18. During the 12-week maintenance period, the percent of patients with 100 percent decrease from baseline partial seizures were 19 percent and 5 percent (Lamictal XR vs. placebo).

The most common (>5 percent) drug-related adverse events for Lamictal XR and placebo, respectively, were dizziness, 18 vs. 5 percent, headache, 17 vs. 15 percent, somnolence, 7 vs. 4 percent, nausea, 7 vs. 2 percent, and diarrhea, 7 vs. 4
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Clinical Study Shows Regenecare Relieves Pain and Itching of Skin Rashes Caused by Widely Used Cancer Drugs
2. International ENDORSE Study Shows That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE prophylaxis
3. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
4. MediGene Announces Cancer-Fighting Virus Shows Promise in Early Clinical Trial
5. Study Shows Ixabepilone Demonstrated Clear Activity in Patients with Metastatic Breast Cancer Resistant to Anthracycline, Taxane, and Capecitabine
6. Ceragenix Compound Shows Promise for Treating Lethal Cystic Fibrosis Infections
7. Largest Cervical Cancer Vaccine Efficacy Trial Shows Cervarix Provides Excellent Protection Against Lesions Caused by Most Common Cancer-Causing Virus Types
8. CombinatoRx Product Candidate CRx-150 Shows Activity on DAS28 and Pain, but Not CRP
9. New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir
10. First Phase II Short-Term Study on Dapagliflozin Shows Results on Safety, Tolerability and Glycemic Markers in Subjects With Type 2 Diabetes
11. New Poll Shows Men, Women Incorrectly Blame Symptoms of Low Testosterone on Normal Aging
Post Your Comments:
(Date:10/20/2014)... YORK and RALEIGH, N.C., Oct. 20, 2014 ... Hereditary Neuropathy Foundation (HNF), both philanthropies, announced today ... drug candidates for the treatment of the rare ... BioPontis Alliance announced its alliance model earlier ... a first demonstration of a collaborative model where ...
(Date:10/19/2014)... MELVILLE, N.Y. , Oct. 19, 2014  Henry ... largest provider of health care products and services to ... that it has invested in Iwase Dental Supply, Inc., ... equipment in Japan.  The transaction marks Henry Schein,s entrance into ... largest dental market, and increases to 28 the ...
(Date:10/17/2014)... 2014 With the recent changes in ... come across several challenges in creating and utilizing ... The Medical Affairs Consortium ... providing benchmarking and best practices across critical Medical ... service composed of three stages: 1) member-driven topic ...
Breaking Medicine Technology:The Hereditary Neuropathy Foundation and BioPontis Alliance for Rare Disease Partner to Develop Treatments for Charcot-Marie-Tooth 2The Hereditary Neuropathy Foundation and BioPontis Alliance for Rare Disease Partner to Develop Treatments for Charcot-Marie-Tooth 3Henry Schein Enters Japan With Investment in Iwase Dental Supply 2Henry Schein Enters Japan With Investment in Iwase Dental Supply 3Henry Schein Enters Japan With Investment in Iwase Dental Supply 4Henry Schein Enters Japan With Investment in Iwase Dental Supply 5Early Key Findings from the Medical Affairs Consortium Research 2
... an international generic pharmaceuticals company, today announced that ... Food & Drug Administration to market Zolpidem Tartrate ... the product has commenced.   Actavis ... Extended-Release Tablets 6.25 mg strength in October 2010 with ...
... 6, 2011 Pharmacyclics, Inc. (Nasdaq: PCYC ... the Phase IB/II study of the Btk inhibitor, PCI-32765, ... (CLL/SLL) at the 2011 American Society of Clinical Oncology ... development program update for the Btk Inhibitor, PCI-32765.  The ...
Cached Medicine Technology:Actavis Receives FDA Approval of Zolpidem Tartrate Extended-Release Tablets USP, 12.5 mg CIV in the U.S. 2Pharmacyclics Reports Recent Developments From Clinical Studies of its Btk Inhibitor PCI-32765 2Pharmacyclics Reports Recent Developments From Clinical Studies of its Btk Inhibitor PCI-32765 3Pharmacyclics Reports Recent Developments From Clinical Studies of its Btk Inhibitor PCI-32765 4Pharmacyclics Reports Recent Developments From Clinical Studies of its Btk Inhibitor PCI-32765 5Pharmacyclics Reports Recent Developments From Clinical Studies of its Btk Inhibitor PCI-32765 6Pharmacyclics Reports Recent Developments From Clinical Studies of its Btk Inhibitor PCI-32765 7Pharmacyclics Reports Recent Developments From Clinical Studies of its Btk Inhibitor PCI-32765 8Pharmacyclics Reports Recent Developments From Clinical Studies of its Btk Inhibitor PCI-32765 9
(Date:10/20/2014)... It’s hard to imagine what it’s like to live without ... world, it’s a reality. And while new shoes are considered ... walk barefoot on rocky terrain or sewage-lined streets just to ... , Buckner International's Shoes for Orphan Souls ... to encourage support for Air1 and while also providing new ...
(Date:10/20/2014)... 2014 Houston plastic surgeon Dr. ... elements of his innovative True Form Tummy Tuck® ... residents and faculty at The University of Texas ... was once a medical student. Patronella, who is a ... plastic surgery practices in Texas, The Aesthetic Center ...
(Date:10/19/2014)... October 20, 2014 Hastings and Hastings, ... years of service throughout the greater Phoenix area and ... representation with regard to catastrophic automobile accidents. Statistics have ... country and throughout Arizona. As such, Hastings and Hastings ... legal representation for those who have been injured through ...
(Date:10/19/2014)... Recently, BambooIndustry.com, one of the most popular suppliers ... bamboo deckings . Moreover, the company has launched ... now available at deeply discounted rates. , As ... overstate the significance of online business nowadays. Thus, BambooIndustry.com ... company’s workers are striving to deliver both value and ...
(Date:10/19/2014)... (PRWEB) October 20, 2014 This ... for Partial Seizure, complete with comparative analysis at ... of action (MoA), route of administration (RoA) and ... news and press releases. It also reviews key ... Seizure and special features on late-stage and discontinued ...
Breaking Medicine News(10 mins):Health News:Buckner Shoes for Orphan Souls® Garners Support from Air1 Radio 2Health News:Buckner Shoes for Orphan Souls® Garners Support from Air1 Radio 3Health News:Plastic Surgeon Patronella Presents Artistically-Inspired Tummy Tuck Method to Future Generation of Plastic Surgeons in Texas 2Health News:Hastings And Hastings Reports Record Demand In 2014 For Legal Representation With Regard To Catastrophic Automobile Accidents 2Health News:Hastings And Hastings Reports Record Demand In 2014 For Legal Representation With Regard To Catastrophic Automobile Accidents 3Health News:High Quality Bamboo Deckings, New Items Unveiled By BambooIndustry.com 2Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 2Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 3Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 4
... , ... discusses naturopathy and alternative medicine in mainstream health care, and the many holistic health ... ... many diverse disciplines that constitute alternative medicine have been around for thousands of years, ...
... 23 Misys, the banking and,healthcare software group, reported continued growth ... group,s full year results have been boosted by a market beating,performance ... In a video interview, CEO Mike Lawrie conceded ... Markets business. , "We did not close ...
... developed a new general anesthetic that may be safer for ... Anesthesiology , they describe preclinical studies of the drug called ... which does not cause the sudden drop in blood ... gland activity, a problem with the original version of the ...
... , , Evidence That Criticisms ... MENLO PARK, Calif., July 23 While Congress works through specific health reform ... remains supportive of taking action on health reform now, though there is some ... , As has been the case over the past ...
... , , LOS ANGELES, July 22 ... is proud to announce the continued success and fast-paced growth in its ... balm that claims to boost energy, suppress hunger and burn fat, recently ... line is turning heads worldwide with orders coming in from as far ...
... carcinogens, other toxins , WEDNESDAY, July 22 (HealthDay ... e-cigarettes, has shown that they contain cancer-causing chemicals ... antifreeze, U.S. health officials said Wednesday. , E-cigarettes ... nicotine, flavorings and other chemicals. "The device turns ...
Cached Medicine News:Health News:Natural Healers Discusses How Alternative Medicine Careers Provide a Little 'Wellness' in a Tough Economy 2Health News:Natural Healers Discusses How Alternative Medicine Careers Provide a Little 'Wellness' in a Tough Economy 3Health News:Mass. General team develops potentially safer general anesthetic 2Health News:Majority of Public Maintains Support for Addressing Health Care Reform Now 2Health News:Majority of Public Maintains Support for Addressing Health Care Reform Now 3Health News:Majority of Public Maintains Support for Addressing Health Care Reform Now 4Health News:Majority of Public Maintains Support for Addressing Health Care Reform Now 5Health News:Burner Balm Gets International Attention 2Health News:E-Cigarettes Pose a Health Hazard, FDA Warns 2Health News:E-Cigarettes Pose a Health Hazard, FDA Warns 3
... System A lower cost alternative to Equalizers, ... multi-sample transfers between two different vessel configurations. With ... spacing can be quickly and easily adjusted for ... plates. Ergonomic Design for Unparalleled Comfort ...
... Exp Expandable Tip System A ... System allows you to perform multi-sample transfers between ... pull of a knob, tip spacing can be ... microcentrifuge tubes) or 96 well plates. Ergonomic ...
... A lower cost alternative to Equalizers, the ... transfers between two different vessel configurations. With the ... can be quickly and easily adjusted for test ... Ergonomic Design for Unparalleled Comfort Pick ...
... Tip System A lower cost alternative to ... perform multi-sample transfers between two different vessel configurations. ... tip spacing can be quickly and easily adjusted ... well plates. Ergonomic Design for Unparalleled Comfort ...
Medicine Products: