Navigation Links
Neuroblastoma Expert Reviews Progress and Challenges in Fighting,Difficult Pediatric Cancer

PHILADELPHIA, June 25, 2007 /PRNewswire-USNewswire/ -- Childhood cancers are fortunately rare, but among them, neuroblastoma is a special case, accounting for 7 percent of all childhood cancers, but 15 percent of childhood cancer deaths. It typically occurs as a solid tumor in the abdomen, but also in the neck, chest, and pelvis, developing in the network of the body's sympathetic nervous system.

Neuroblastoma is what physicians call a heterogeneous disease; its name includes subtypes of disease that behave very differently. Some cases strike in infants, but spontaneously disappear with minimal treatment, while other cases in older children may be relentlessly aggressive from the start. So precisely defining a given patient's risk level can help oncologists design the best treatment, avoiding the twin pitfalls of undertreating or overtreating any given child.

Better treatments may be on the horizon, but better understanding of neuroblastoma's precise biology can guide physicians to the best choices among possible options.

John Maris, M.D., of The Children's Hospital of Philadelphia, describes the current status of neuroblastoma treatment and trends for the near future, in the June 23 issue of the British journal Lancet. Maris is among the world leaders in neuroblastoma research, with a lab holding tissue samples from 5,000 patients -- the world's largest sample collection for the disease.

In his paper, Maris reviews new approaches to treatments for a particularly challenging set of patients -- children whose neuroblastoma has relapsed in an aggressive form. One particular technique being used and studied at Children's Hospital employs radioactive isotopes that zero in on neuroblastoma cells to selectively kill those cells with radiation. Other tools include retinoids -- biological molecules that hone in on cancer cells, angiogenesis inhibitors that cut off a tumor's blood supply, and
'"/>




Page: 1 2 3

Related medicine technology :

1. In Vitro and In Vivo Data Show Alfacells Onocanse is Active Against Naive and Chemoresistant Neuroblastoma Cells
2. Researchers Use Poliovirus to Destroy Neuroblastoma Tumors in Mice
3. Expert Opinion Highlights Avigens AV411 as Potential New Therapeutic for Neuropathic Pain and Opioid Withdrawal
4. Reatas Synthetic Triterpenoids Profiled in Nature Reviews Cancer
5. Pieris Progresses Proprietary Asthma Program: Validation of Pulmonary Delivery of Anticalin-Based Protein Product Candidate
6. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
7. Pieris Progresses Development of its Proprietary Biotherapeutics Platform: Successful Demonstration of Dual Targeting With Duocalin(R) Technology
8. Biodel Inc. to Present VIAject Clinical Progress at the 2007 American Diabetes Association Meeting
9. Can-Fite Proceeds with Development of Third Drug; Progress in Development of CF502 Will Be Presented at the Annual European Congress of Rheumatology
10. Treating Heart Disease Risk Factors May Slow Alzheimers Disease Progression
11. Caelyx Delays Time to Disease Progression as Maintenance Therapy in Patients with Metastatic Breast Cancer
Post Your Comments:
(Date:9/29/2014)... SAN DIEGO , 29 septembre ... désignée Daiichi Sankyo) (TSE : 4568) et Ambit Biosciences ... d,un accord de fusion définitif en vertu duquel ... actions ordinaires en circulation d,Ambit Biosciences à 15 ... d,une offre publique d,achat qui sera suivie d,une ...
(Date:9/29/2014)...  Bob Pack, who lost his two young children ... Medical Association to immediately cease airing a television ad ... Mercury News called "shamelessly deceptive" and of which the ... believe about the measure is wrong." ... that doctors check California,s existing ...
(Date:9/29/2014)... Sept. 29, 2014  Volcano Corporation (Nasdaq: ... improving patient and economic outcomes on a global ... coronary and peripheral visualization, physiology diagnostics and therapies, ... Board of Directors from Engaged Capital, LLC.  The ... Volcano welcomes the perspectives of its ...
Breaking Medicine Technology:Daiichi Sankyo va acquérir Ambit Biosciences 2Daiichi Sankyo va acquérir Ambit Biosciences 3Daiichi Sankyo va acquérir Ambit Biosciences 4Daiichi Sankyo va acquérir Ambit Biosciences 5Daiichi Sankyo va acquérir Ambit Biosciences 6Daiichi Sankyo va acquérir Ambit Biosciences 7Daiichi Sankyo va acquérir Ambit Biosciences 8Daiichi Sankyo va acquérir Ambit Biosciences 9Father Calls On CA Medical Assn To Pull TV Ad Called "Jaw-Droppingly Deceptive" and "Baloney" By LA Times & "Shamelessly Deceptive" By San Jose Mercury News, Says Consumer Watchdog Campaign 2Father Calls On CA Medical Assn To Pull TV Ad Called "Jaw-Droppingly Deceptive" and "Baloney" By LA Times & "Shamelessly Deceptive" By San Jose Mercury News, Says Consumer Watchdog Campaign 3Father Calls On CA Medical Assn To Pull TV Ad Called "Jaw-Droppingly Deceptive" and "Baloney" By LA Times & "Shamelessly Deceptive" By San Jose Mercury News, Says Consumer Watchdog Campaign 4Father Calls On CA Medical Assn To Pull TV Ad Called "Jaw-Droppingly Deceptive" and "Baloney" By LA Times & "Shamelessly Deceptive" By San Jose Mercury News, Says Consumer Watchdog Campaign 5Volcano Issues Statement Regarding Letter From Engaged Capital 2Volcano Issues Statement Regarding Letter From Engaged Capital 3
... studied the treatment of pregnant women with hepatitis B virus ... study concluded that both the mothers benefited from treatment and ... weeks postbirth. The study presenter and co-investigator Calvin ... as hepatitis B is difficult to eradicate and currently there ...
... POINT, Calif., Nov. 1, 2010 The Global ... organization that aims to raise awareness about the ... 7,000 Bracelets for Hope™ campaign. The 7,000 Bracelets ... to an estimated 7,000 different chronic, life-threatening and ...
Cached Medicine Technology:Telbivudine Given to Mothers With Hepatitis B Reduces Infection Rate in Infants 2Telbivudine Given to Mothers With Hepatitis B Reduces Infection Rate in Infants 37,000 Bracelets For Hope™ - A Rare Disease Awareness Campaign 27,000 Bracelets For Hope™ - A Rare Disease Awareness Campaign 3
(Date:9/30/2014)... MN (PRWEB) September 30, 2014 ... leader in business technology and services was recognized ... First Call Effectiveness (FCE) in 2013. This prestigious ... properly the first time and for an extended ... For more than 20 years BEI Services has ...
(Date:9/30/2014)... Barbara Williamson shares her life story for the first ... Love, Sex and Commitment" . As co-founder with her ... successful and controversial Sandstone Retreat in Malibu, California, in ... what became known as the hub of the sexual ... popular, with a membership reaching 500 and nearly 8,000 ...
(Date:9/30/2014)... 2014 From October 12-15, MMS, ... the 2014 SHSMD Connections Annual Conference in San Diego, ... & Market Development (SHSMD) is proud to host the ... and communications, and strategic planning professionals in San Diego ... , The conference is a four-day event designed ...
(Date:9/30/2014)... Seattle, WA (PRWEB) September 30, 2014 ... Intelligence, proudly announced today that the Department of ... Office as its Enterprise End User Business ... to better support our nation’s veterans by enabling ... obtained through BI Office’s powerful enterprise analytics and ...
(Date:9/30/2014)... San Francisco, CA (PRWEB) September 30, 2014 ... places its main focus on ranking and reviewing all ... This website has officially announced the best liquid foundation ... Youth Liberator Serum Foundation is named as the best ... foundations cover drugstore as well as high end brands, ...
Breaking Medicine News(10 mins):Health News:Loffler Companies Rated Number One Among U.S. Dealers in Service “First Call Effectiveness” 2Health News:Loffler Companies Rated Number One Among U.S. Dealers in Service “First Call Effectiveness” 3Health News:The Autobiography "An Extraordinary Life: Love, Sex and Commitment" Embraces Healthy Sexual Behavior 2Health News:The Autobiography "An Extraordinary Life: Love, Sex and Commitment" Embraces Healthy Sexual Behavior 3Health News:MMS, Inc. (Medical Marketing Service) to Attend the 2014 SHSMD Connections Annual Conference in October 2Health News:U.S. Department of Veterans Affairs Takes Its Analytic Capabilities to the Next Level with BI Office from Pyramid Analytics 2Health News:Yves Saint Laurent is Named As Best Liquid Foundation 2014 2
... in heart attack or mortality rates , , SUNDAY, Nov. 4 ... to date, Harvard researchers report that they have found drug-eluting ... than bare metal stents do. , "There has been a ... investigator Dr. Laura Mauri, an assistant professor of medicine at ...
... ... Heart Association,s Scientific Sessions 2007 ... 4 , WHO: Dr. Amir Lerman, Professor of Medicine, Mayo Clinic, Rochester, MN ... Sweden Mr. Israel Schreiber, President ...
... North Carolina team of doctors, nurses, hospitals and emergency ... to provide faster, more effective treatment for heart attack ... fancy new equipment. But it does require competitors to ... move treatment forward empowering emergency services personnel in ...
... props open closed aortas in older patients, research suggests ... high-risk heart patients with narrowed aortas who typically need ... option -- an implanted, balloon-expandable aortic valve. , The ... the problem valve and then inflated, experts said. In ...
... increase in their risk of heart attacks or other ... the largest-ever study of the issue, being presented at ... Scientific Exposition in San Francisco. , Although donors are ... (hypertension) during follow-up, it is unclear whether this represents ...
... Union Election, Note Hospital System Failing ... to Live Up to its Own ... elected officials and other healthcare activists joined hospital,workers from the St. ... Hospital on Saturday, where they called for the health,system,s leadership to ...
Cached Medicine News:Health News:Drug-Coated Stents No Riskier in Long Run Than Bare Metal Ones 2Health News:Drug-Coated Stents No Riskier in Long Run Than Bare Metal Ones 3Health News:How Early Can We Detect Cardiovascular Disease Less Expensively ... Even in Childhood? 2Health News:RACE: a statewide model of better, faster heart attack care 2Health News:RACE: a statewide model of better, faster heart attack care 3Health News:Balloon Valve May Be Alternative to Open-Heart Surgery 2Health News:Balloon Valve May Be Alternative to Open-Heart Surgery 3Health News:No increase in cardiovascular risk for living kidney donors 2Health News:Healthcare Workers, Community Activists Call for Fair Election Agreement at St. Joseph Health System 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: