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Mymetics' HIV Vaccine Achieves Research Breakthrough, Eliciting,Protective Antibody Response in Mucosal Tissues of Non-Human,Primate Model

Mymetics Also Announces Deal for Vaccine Delivery System

NYON, Switzerland, March 29, 2007 /PRNewswire-FirstCall/ -- Mymetics Corporation announced today that the Company's HIV vaccine elicited IgA mucosal antibodies in a non-human primate model. Mucosal IgA antibodies are considered a possible first line of defense against infection by HIV. The data were presented by Sylvain Fleury, Ph.D., Mymetics' Chief Scientific Officer in an oral presentation, "Without Mucosal Adjuvant, Virosomes-gp41 Peptides from the MPR can Elicit Protective Mucosal IgA in Vaccinated Macaques," at the Keystone Symposium, HIV Vaccines: From Basic Research to Clinical Trials. The meeting is being supported by the Bill & Melinda Gates Foundation.

"The results are a striking example of the progress we have seen in applying our vaccine based on the gp41, a well-conserved HIV surface membrane protein," commented Dr. Fleury. "Previously, our team was the first to be able to synthesize a trimeric, soluble and stable formulation of gp41 that could be used in a vaccine. Now, by showing that we can elicit IgA mucosal antibodies in vaginal and rectal tissues, we have taken a major step in being able to prepare materials for a submission to begin studies in human patients. We expect that this submission could take place as early as the third quarter of 2008."

Mymetics also announced that it has signed an exclusive license with Pevion Biotech for the use of Virosomes(R) in the production of its HIV vaccine. Virosomes are a market-approved carrier system for the delivery of pharmaceutically or immunologically active substances, allowing the correct spatial presentation of peptides and proteins and facilitating delivery of Mymetics' HIV vaccine without the use of an adjuvant. Additional details were not disclosed.

Christian Rochet, Mymetics' President and Chief Executive Officer, stated, "We believe that our exclusive agreemen
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