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Molecular Insight Pharmaceuticals, Inc. Presents Preclinical Data,at Society Of Nuclear Medicine 2007 Annual Meeting

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Jun 4, 2007 - Molecular Insight Pharmaceuticals, Inc. (NASDAQ: MIPI) announced today that the company will present the results of several preclinical studies at the 54th annual meeting of the Society of Nuclear Medicine (SNM) in Washington, D.C. The presentations include data on Azedra(TM) (Ultratrace (131)I-MIBG), the company's clinical-stage, targeted radiotherapeutic candidate for the treatment of malignant neuroendocrine tumors; Zemiva, its lead molecular imaging pharmaceutical for imaging cardiac ischemia; and MIP-190, its molecular imaging pharmaceutical candidate that targets angiotensin converting enzyme for the detection of heart failure and vascular inflammatory disease. Data on the company's radiolabeled small molecule molecular imaging pharmaceutical, MIP-1072, for the detection and staging of prostate cancer, were presented on June 3rd. -0-
Abstract Title: Formulation comparisons and pharmacokinetics of high

                specific activity Ultratrace 131I-Iobenguane (mIBG)

                for therapy


Authors:        J. F. Kronauge(a1), J. A. Barrett(1), J. Qi(1),

                H. Mok(1), D. H. Hunter(2), C. Bensimon(4),

                S. Oelsner(4), J. P. Norenberg(3), T. Anderson(3),

                S. Gallo(1), S. M. Hiller(1), J. Joyal(1),

                N. S. Lee(1) and J. W. Babich(1);

                1. Molecular Insight Pharmaceuticals, Inc., Cambridge,

                Massachusetts; 2. University of Western Ontario,

                London, Ontario, Canada; 3. University of New Mexico,

                Albuquerque, New Mexico and 4. MDS Nordion, Kanata,

                Ontario, Canada.


Reference #:    335357


Publication No.: 1316 - Scientific Poster Session


Poster Section:  Dosimetry/Radiobiology Posters


Session Info:   "Meet the Author" II: Neurosciences, General Clinical

                Specialties, and Radiopharmaceutical Chemistry Posters

                Monday, June 4

    
            3:15 PM- 4:00 PM

                Hall E


-0-

Abstract Title: A comparison of Iodine-123 and Technetium-99m assays

                using dose calibrators


Authors:        D. L. Yokell(a), J. F. Kronauge, C. S. Kao and J. W.

                Babich; Development, Molecular Insight

                Pharmaceuticals, Inc., Cambridge, Massachusetts.


Reference #:    335015


Publication No.: 1835 - Scientific Poster Session


Poster Section: Instrumentation Posters


Session Info:   "Meet the Author" IV: Instrumentation & Data Analysis

                Posters

                Tuesday, June 5

                1:15 PM - 2:00 PM

                Hall E

-0-

Abstract Title: Synthesis and evaluation of a series of M(CO)3+

                (M=Tc,Re) lisinopril complexes for imaging angiotensin

                converting enzyme (ACE)


Authors:        F. J. Femia(a1), K. P. Maresca(1), S. M. Hillier(1),

                C. N. Zimmerman(1), J. L. Joyal(1), J. A. Barrett(1),

                T. Coleman(2), O. Aras(2), C. A. Foss(3),

                M. G. Pomper(3), V. Dilsizian(2), W. C. Eckelman(1)

                and J. W. Babich(1); 1. Molecular Insight

                Pharmaceuticals, Inc., Cambridge, Massachusetts;

                2. Nuclear Medicine, University of Maryland,

                Baltimore, Maryland and 3. Radiology, Johns Hopkins

                Medical Institutions, Baltimore, Maryland.


Reference #:    331898


Publication No.: 613 - Scientific Paper Session (Oral)


Session Info:   New Chemistry-Other II

                Wednesday, June 6

                9:45 AM - 11:15 AM

                Room 145A

On June 3rd, researchers at Molecular Insight also presented preclinical data on MIP-1072, a radiolabeled, small molecule molecular imaging pharmaceutical in development for diagnosis and staging of prostate cancer. MIP-1072 is designed to target prostate specific membrane antigen (PSMA), a protein found predominantly on prostate tumor cells. The paper, "Molecular Targeting of Prostate Cancer with Small Molecular Inhibitors of Prostate Specific Membrane Antigen," was honored by SNM with the 2007 Berson-Yalow Award for most original scientific abstract.

About Molecular Insight Pharmaceuticals, Inc.

Molecular Insight Pharmaceuticals (NASDAQ: MIPI) is a biopharmaceutical company specializing in the emerging field of molecular medicine, applying innovations in the identification and targeting of disease at the molecular level to improve healthcare for patients with life-threatening diseases. The company is focused on discovering, developing and commercializing innovative and targeted radiotherapeutics and molecular imaging pharmaceuticals with initial applications in the areas of oncology and cardiology. Its lead targeted radiotherapeutic product candidates, Azedra and Onalta, are being developed for detection and treatment of cancer. The company's lead molecular imaging pharmaceutical product candidate, Zemiva, is being developed for the diagnosis of cardiac ischemia, or insufficient blood flow to the heart. In addition, the company has a growing pipeline of product candidates resulting from application of its proprietary platform technologies to new and existing compounds. Molecular Insight Pharmaceuticals is based in Cambridge, Massachusetts and its website address is: www.molecularinsight.com.

Forward-Looking Statements

Statements in this release that are not strictly historical in nature constitute "forward-looking statements." Such statements include, but are not limited to, statements about the development of Azedra(TM), Onalta (TM), Zemiva(TM) and our other product candidates. Such forward-looking statements involve known and unknown risks, uncertainties, and other factors that may cause the actual results of Molecular Insight to be materially different from historical result s or from any results expressed or implied by such forward-looking statements. These factors include, but are not limited to, risks and uncertainties related to the progress, timing, cost, and results of clinical trials and product development programs; difficulties or delays in obtaining regulatory approval for product candidates; competition from other pharmaceutical or biotechnology companies; and the additional risks discussed in filings with the Securities and Exchange Commission. All forward-looking statements are qualified in their entirety by this cautionary statement, and Molecular Insight undertakes no obligation to revise or update this news release to reflect events or circumstances after the date hereof.

Contact

Molecular Insight Pharmaceuticals, Inc.
Priscilla Harlan, 617-492-5554
Vice President, Corporate Communications
& Investor Relations


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