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Mircera Effective in Stabilising Haemoglobin Levels in Elderly,Patients With Kidney Disease on Dialysis

lready been on dialysis from 33 to 40 months. The study also found a higher transfusion requirement in elderly patients. A significant number of patients entering the study suffered from diabetes (more than 35 per cent) and arterial hypertension (more than 90 per cent) -- two of the main causes of CKD and among the most common co-morbid conditions in CKD patients.

The results showed that intravenous (IV) and subcutaneous (SC) MIRCERA maintained stable Hb levels in dialysis patients over and under 65 years of age who were successfully switched from the frequently administered agents, epoetin alfa and beta. The study investigators also noted:

-- Minimal changes from baseline to evaluation in mean Hb levels in patients less than or equal to 65 and >65 years (-0.18 vs -0.34 g/dL), meaning that the elderly can be treated with confidence.

-- Minimal mean Hb changes from baseline to evaluation in male and female patients treated with MIRCERA (-0.21 vs -0.30 g/dL).

MIRCERA treatment was well tolerated, with a safety profile characteristic of the patient population.

"With more elderly people needing dialysis treatment, doctors will need effective medications that can improve the way we manage renal anaemia. These findings underscore the value of MIRCERA in meeting a goal of anaemia management, namely haemoglobin stability," said Dr. Elias David Neto, Centro de Nefrologia e Transplante Renal, University of Sao Paulo, Sao Paulo, Brazil.

Bearing the Burden of Chronic Kidney Disease: The Prevalence of Dialysis in an Aging Population

Dialysis is the only treatment option for end stage renal disease patients who are either waiting for or not a candidate for a renal transplant. The number of people over the age of 65 with end stage renal disease is on the rise because of an aging population and the diabetes epidemic.(ii),(iii) In fact, more than 50 percent of the people on dialysis are over 60 years of age.(iv) Further, it is known t
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