Navigation Links
Medtronic Updates Long-Term ENDEAVOR I-II Clinical Data Showing,Sustained Safety and Significant Reductions in Repeat Procedures

BARCELONA, Spain--(BUSINESS WIRE)--May 22, 2007 - Medtronic (NYSE:MDT) today presented new long-term data from the ENDEAVOR clinical trial program reinforcing the existing safety and efficacy profile of the Endeavor(R) drug-eluting coronary stent system. Four-year results from the 100-patient first-in-man ENDEAVOR I trial and three-year results from the nearly 1,200 patient ENDEAVOR II trial demonstrate that Endeavor is associated with sustained safety, significant reductions in repeat procedures and no late stent thrombosis in either trial using the pre-specified trial protocol definitions. The ENDEAVOR II study also showed that the Medtronic Driver(R) bare metal stent offers consistent and durable long-term clinical results.

The data was presented by Andreas Zeiher, M.D., J.W. Goethe-University, Frankfurt, Germany, during the EuroPCR's late-breaking clinical trial session. The Endeavor stent is approved in more than 100 countries worldwide and currently is under review by the U.S. Food and Drug Administration. FDA approval is anticipated in the second half of 2007.

The ENDEAVOR I data continue to show excellent long-term results, with only one clinical event between years three and four, a non-cardiac death from cancer. Target Lesion Revascularization (TLR) at four years was 3.1% and Target Vessel Revascularization (TVR) was 5.2%. The Major Adverse Cardiac Event (MACE) rate, one of the trial's primary endpoints, was 7.2%, with no late stent thrombosis events in this patient cohort.

Through three years of follow-up in the ENDEAVOR II trial, the TLR rate was 7.3%, compared to 14.7% for the Driver bare metal control arm (p= less than 0.001), representing a 50% reduction in the need for repeat procedures. Target Vessel Failure, the trial's primary endpoint, was 12.8% for Endeavor and 21.4% for Driver, a 40% reduction (p= less than 0.001). Endeavor showed a MACE rate of 12.0% at three years, compared
'"/>




Page: 1 2 3

Related medicine technology :

1. Medtronic Announces Positive Nine-Month Results for Endeavor Resolute Next Generation Drug-Eluting Stent at EuroPCR
2. Study Supports Cost-Effectiveness of Medtronics Spasticity Treatment for Children with Cerebral Palsy
3. Two-Year Results from the Medtronic ENDEAVOR III Trial Confirm Stents Positive Clinical Profile
4. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
5. Avalon Updates the AVN944 Phase I Hematologic Malignancies Trial
6. NCCN Updates Esophageal and Gastric Cancer Guidelines
7. Isis Pharmaceuticals Updates Its Positive Phase 2 Data for ISIS 301012 in Familial Hypercholesterolemia Patients
8. Anesiva Announces Phase 2 Data Showing Substantial, Long-Term Pain Reductions with Adlea(TM) (formerly 4975) in Osteoarthritis of the Knee
9. Long-Term Pegylated Interferon Alfa-2b Therapy in Stage III Melanoma Demonstrated Significant and Sustained Impact on Relapse-Free Survival
10. Surfaxin (Lucinactant) Long-Term Survival Advantage vs. Comparators Published in Pediatrics
11. Long-Term Extension of Ulcerative Colitis Study Shows Remicade Responders Maintained Improvement Through Two Years of Follow-Up
Post Your Comments:
(Date:8/19/2014)... , Aug. 19, 2014   Lincor Inc. ... patient experience technology to New Jersey ... five-year agreement, CarePoint Health will deploy Lincor,s PatientLINC ... Center, Christ Hospital and Hoboken University Medical Center. ... range of software solutions to help hospitals reach ...
(Date:8/19/2014)... -- Northwest Biotherapeutics (NASDAQ: NWBO ) (NW Bio), ... solid tumor cancers, announced today that the $17.5 million ... has closed.  The three-year notes have a 5% interest ... common stock.  The investors also have an option, exercisable ... 30% of these notes on the same terms. ...
(Date:8/19/2014)... 2014 Research and Markets has ... - Global Strategic Business Report" report to their ... markets for Pharmaceutical Contract Manufacturing in US$ Thousand by ... solutions), Solid Dosage Forms (Tablets and Capsules), and Liquid ... Ointments). The report provides separate comprehensive analytics ...
Breaking Medicine Technology:Lincor Announces Agreement With CarePoint Health For State-Of-The-Art Patient Engagement Technology 2NW BIO COMPLETES THE CLOSING OF ITS $17.5 MILLION CONVERTIBLE NOTE OFFERING 2NW BIO COMPLETES THE CLOSING OF ITS $17.5 MILLION CONVERTIBLE NOTE OFFERING 3Global Pharmaceutical Contract Manufacturing - Strategic Business Report 2014 2
(Date:8/20/2014)... common cause of endophthalmitis, a potentially blinding condition that ... injections, are the well-known staphylococci ("staph") and ... study published in the August issue of Ophthalmology ... of cases at New York Eye and Ear Infirmary ... found that gram-positive bacteria, which include staph and strep ...
(Date:8/20/2014)... The non-small cell lung cancer (NSCLC) market value ... the top 8 developed nations, from just over USD ... billion by 2020-end, posting a CAGR of 6.6% during ... driven by innovative therapies entering the squamous cell carcinoma ... the non-squamous segment. Thus, patients with SCC are expected ...
(Date:8/20/2014)... Caddis Partners LLC, has built one of the ... company in recent years, developing or acquiring 2 million ... including more than $100 million last year alone. , ... new geographic regions and a wider array of product ... announce an enhanced brand identity that includes a new ...
(Date:8/20/2014)... Angeles, CA (PRWEB) August 20, 2014 ... it is bringing on Wrench Advisors as a ... tasks including international large accounts. , As Wrench ... sales consultants can help your organization plan and ... executives and global distribution channels. Our experience developing ...
(Date:8/20/2014)... The award-winning plastic surgery group, The Aesthetic Center ... Houston to a third office, located in Katy, Texas ... ACPS plastic surgeon Dr. Rolando Morales said the expansion ... risen to become one of the largest, most respected ... its establishment in 1996 by plastic surgeons Dr. Christopher ...
Breaking Medicine News(10 mins):Health News:Researchers pinpoint most common causes of dangerous eye infection post surgery and trauma 2Health News:Researchers pinpoint most common causes of dangerous eye infection post surgery and trauma 3Health News:Top 8 Developed Nations NSCLC Market to Grow at CAGR of 6.6% Through 2020, Says GBI Research in Its Report Published at MarketPublishers.com 2Health News:Top 8 Developed Nations NSCLC Market to Grow at CAGR of 6.6% Through 2020, Says GBI Research in Its Report Published at MarketPublishers.com 3Health News:Top 8 Developed Nations NSCLC Market to Grow at CAGR of 6.6% Through 2020, Says GBI Research in Its Report Published at MarketPublishers.com 4Health News:Caddis Rebrands to Emphasize Its Growth, Expanded Capabilities 2Health News:Caddis Rebrands to Emphasize Its Growth, Expanded Capabilities 3Health News:Caddis Rebrands to Emphasize Its Growth, Expanded Capabilities 4Health News:Biocide Systems Announces Partnership with Wrench Advisors 2Health News:Aesthetic Center for Plastic Surgery Expands Its Reach in Texas 2
... Vision ... Expand Access to Care, WASHINGTON, April 9, 2008 ... health care,policy issues by doctors of optometry from his district ... in West Virginia and the AOA are working to pass ...
... 9 Nu Skin Enterprises,Inc. (NYSE: NUS ) ... the market opening on Thursday, May 1, 2008., ... a,conference call with the investment community later that same ... can expect to hear,management review past results and discuss ...
... housework, is good for mental health , , WEDNESDAY, April 9 (HealthDay ... clean your house and boost your mood. , In ... activity a week helped mental health, although the more vigorous the ... published online Thursday in the British Journal of Sports Medicine ...
... 9 The following statement,was issued today by William ... York,s leaders have taken historic action to protect the ... use by increasing,the state cigarette tax by $1.25 to ... tax increase ever enacted and gives New York the,highest ...
... One month of tough breathing may help asthma sufferers breathe ... University of Houston professor. , In a move ... Hippocratic Oath first do no harm Richard Bond, ... long-standing medical taboo to treat asthma. Although counterintuitive, Bonds ...
... may also identify children at risk , , WEDNESDAY, April ... responsible for cardiac hypertrophy (thickening of the heart muscle) ... this rare but life-threatening condition in children, says a ... children who had no family history of the condition, ...
Cached Medicine News:Health News:Sen. Robert Byrd Receives AOA Health Care Leadership Award 2Health News:Whisk Those Blues Away 2Health News:New York Cigarette Tax Increase Delivers Victory for Kids and Taxpayers 2Health News:First do no harm? UH prof taking opposite approach to treat asthma 2Health News:First do no harm? UH prof taking opposite approach to treat asthma 3Health News:First do no harm? UH prof taking opposite approach to treat asthma 4Health News:Gene Mutations for Rare Heart Disease Also Found in Kids 2
Sedillot periosteal elevator, 16 mm, sharp, 7"....
Periosteal elevator #9H, 17.5 cm, 7"....
Obwegeser periosteal elevator, angled, 9 mm, 20 cm, 8"....
... The Anterior Isola System is ... scoliotic, lordotic or kyphotic spinal ... stiff fixation bridge parallel to ... spine. The system, developed for ...
Medicine Products: