( s the strengths of the Endeavor stenta...)Medtronic Announces Positive Nine-Month Results for Endeavor,Resolute Next Generation Drug-Eluting Stent at EuroPCR,Health

s the strengths of the Endeavor stent and introduces BioLinx, a proprietary, biocompatible polymer designed by Medtronic scientists. BioLinx is different from other polymers in that its outer surface is hydrophilic (water friendly), which leads to high biocompatibility with the body. At the same time, the interior of the polymer is hydrophobic, which helps to control the drug release. Some polymers can produce an inflammatory response within the blood vessel. This can contribute to thrombosis or occlusion of the artery - outcomes that are more pronounced in patients with difficult lesions or complex medical conditions. BioLinx is a non-inflammatory polymer blend that mimics the make-up of a cell membrane to maintain biocompatibility.

"The Medtronic drug-eluting stent product pipeline is extremely strong, with clinical trial results that demonstrate an impressive combination of safety and effectiveness," said Scott Ward, president of the CardioVascular business at Medtronic. "Endeavor RESOLUTE is designed to complement Endeavor and provide physicians with a compelling choice of drug-eluting stents to match the specific needs of their patients. Medicine is very personal and these data clearly reinforce that we are achieving our mission of providing doctors with the products they need to provide the best possible care for their patients with coronary artery disease."

Two articles on the Medtronic RESOLUTE trial and the Endeavor Resolute stent will be published this week in the medical journal EuroIntervention. They are: "The next-generation Endeavor(TM) Resolute stent: 4-month clinical and angiographic results from the Resolute first-in-man trial," authored by Dr. Meredith and others; and "The Next Generation ENDEAVOR RESOLUTE Stent: Role of the BioLinx(TM) Polymer System," authored by Kishore Udipi, Medtronic Director of Polymer Research, and others.

The Endeavor Resolute stent is not yet approved in any country. Data from the Endeavor RESOLUTE cl
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