Navigation Links
MedImmune Highlights Advances in Inflammatory Disease Pipeline With,Series of Data Presentations

Data Include Results from Phase 1 Studies with Monoclonal Antibody Targeting Interleukin-9 (IL-9); Preclinical Data Provide Further Rationale for IL-9 Inhibition in Developing Potential Asthma Therapies

GAITHERSBURG, Md., May 24, 2007 /PRNewswire-FirstCall/ -- MedImmune, Inc. today announced the presentation of data highlighting recent progress within the company's inflammatory disease pipeline, including results from two Phase 1 clinical studies with its monoclonal antibody (MAb) targeting IL-9 and preclinical data demonstrating a central role for IL-9 in the pathology of asthma. These data, along with preclinical results from other respiratory inflammation programs within MedImmune's pipeline, were presented during the American Thoracic Society (ATS) 2007 International Conference, held May 18-23 in San Francisco, CA. Preclinical results were also presented this week at the 94th Annual Meeting of The American Association of Immunologists (AAI), held May 18-22 in Miami Beach, FL.

The IL-9 protein is implicated in a range of characteristic features of asthma, including increased airway inflammation, obstruction and hyperresponsiveness, mucin production and mast cell generation. Earlier preclinical study results have demonstrated that inhibition of IL-9 leads to decreased airway inflammation and hyperresponsiveness in animal models. The clinical results presented at ATS show that the anti-IL-9 MAb was well tolerated and support further study of the antibody in multiple-dose studies in patients with asthma.

"We are very encouraged by these clinical results, which provided the impetus for MedImmune to initiate a Phase 2 trial with our anti-IL-9 MAb and underscore our ongoing commitment to advancing potential treatments for respiratory inflammatory diseases," said Barbara White, M.D., vice president, clinical development, inflammatory disease. "Additionally, as we expand our body of knowledge about IL-
'"/>




Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Infinity and MedImmune Present Updated Phase I Results of IPI-504 in GIST at ASCO Annual Meeting
2. Infinity and MedImmune Announce Updated Data On Ipi-504 to be Presented At ASCO
3. MedImmune Announces Positive Clinical Results at PAS Annual Meeting From Large Prospective Trial in Prevention of Serious RSV Disease
4. Pediatric Academic Societies Annual Meeting to Feature Data Presentations Related to MedImmune Clinical Programs in Influenza, RSV and hMPV
5. Micromet Achieves Milestone in BiTE Research Collaboration with MedImmune
6. MedImmune Publishes New Data in Nature Immunology Demonstrating The Role HMGB1 May Play in Systemic Autoimmune Diseases
7. MedImmune and Micromet Publish Data on Novel Anti-Cancer BiTE Molecule
8. Micromet and MedImmune Present Data From Preclinical Study of New BiTE Molecule Targeting CEA
9. Infinity and MedImmune to Present Preclinical Data From Study of Oral Formulation of IPI-504 At AACR
10. BusinessWeek Article Highlights Promising Breakthrough Treatment for Advanced Coronary Artery Disease
11. BusinessWeek Article Highlights Promising Breakthrough Treatment for Advanced Coronary Artery Disease
Post Your Comments:
(Date:8/28/2015)... N.C. , Aug. 28, 2015  Delays ... research projects can slow down the decision-making process, ... is, therefore, absolutely critical for biopharmaceutical companies to ... research approval process for quicker and more meaningful ... by Best Practices, LLC, nearly three-quarters of benchmarked ...
(Date:8/28/2015)... DUBLIN , Aug. 28, 2015 ... announced the addition of the "Investigation Report on ... Developed by Roche under the trade name ... in the world. In Feb.26, 2010, it was approved ... injections available in China all ...
(Date:8/28/2015)... 28, 2015 Patterson Medical, formerly the ... PDCO ), is now an independent company with ... Patterson Medical by Madison Dearborn Partners (MDP).  ... for a transition period before rebranding as the ... medicine products.  With the focused resources and expertise ...
Breaking Medicine Technology:Expediting the Pharmaceutical Market Research Process for Faster Insights 2Investigation Report on China's Bevacizumab Market 2015-2019 2Patterson Medical Positioned for Continued Growth as a Newly Independent Company 2Patterson Medical Positioned for Continued Growth as a Newly Independent Company 3
... KONG, Oct. 11 OrbusNeich today reported the completion ... its Genous Bio-engineered R stent at 11 sites in ... patient, controlled study is to demonstrate the safety and ... the Medtronic Endeavor® Sprint stent in patients with symptoms ...
... BioStorage Technologies, a global leader in sample management, ... pharmaceutical and biotechnology industries, has expanded its sample ... including sample aliquoting and nucleic acid extraction and ... sample management continues to grow, BioStorage Technologies has ...
Cached Medicine Technology:Randomized Clinical Trial of OrbusNeich's Genous™ Bio-engineered R stent™ in China Completes Patient Enrollment 2Industry Leader BioStorage Technologies Broadens Sample Management Operations to Include Laboratory Sample Preparation Services 2
(Date:8/29/2015)... ... , ... The popular television program VOICES IN AMERICA, hosted by legendary star ... devoting an entire short segment to the subject of diabetes. Diabetes is a debilitating ... daily basis, but recent advancements in medical science may prove to be a significant ...
(Date:8/28/2015)... , ... August 28, 2015 , ... An online provider ... to make the purchase of CPAP equipment more affordable by offering shipping at no ... types of CPAP products and orders of any size. My Cpap Store is located ...
(Date:8/28/2015)... ... August 28, 2015 , ... With the goal of furthering music education programs ... to the Adams County Fairgrounds in Mendon, IL on May 30th, 2015. Backed once ... music education in the underfunded school districts of Mendon and its neighboring town of ...
(Date:8/28/2015)... ... ... The 6th Annual Survivor in the City, Chicago silent auction and ... to its cadre of widespread support—an official letter of support and gratitude from the ... community and the University of Illinois at Chicago’s Department of Neurosurgery, the Brain Aneurysm ...
(Date:8/28/2015)... ... August 28, 2015 , ... “ Frequentz ” was featured ... latest and coolest applications on the market for iOS, Android, and Windows. Joe Toohey, ... viewers how this software allows businesses to track product movement from beginning to end. ...
Breaking Medicine News(10 mins):Health News:My Cpap Store Now Offering Delivery Special 0 Cost to You 2Health News:Best Drug Rehabilitation Interviews Country-Rock Duo Highway Run at the 2015 "Music With A Mission" Benefit Concert 2Health News:Chicago Mayor Pens Official Support of Annual Survivor in the City Event Benefitting Brain Aneurysm Foundation 2Health News:Chicago Mayor Pens Official Support of Annual Survivor in the City Event Benefitting Brain Aneurysm Foundation 3Health News:Track Product Movement from Beginning to End with Frequentz 2
... Reporter , THURSDAY, June 24 (HealthDay News) -- Scientists have succeeded ... of an old one in rats. The researchers, reporting ... day to replicate the feat in humans, giving hope to the ... (COPD) and perhaps even lung cancer. But that could take ...
... trial of a novel radioactive compound readily and safely ... volunteers on brain scans and opens the doors to ... their own radioactive compounds. The results, reported by a ... Nuclear Medicine, could lead to better ways to ...
... study done by researchers at Wake Forest University Baptist Medical ... mean a hospital stay there is another option for ... cases, allows the patient to return home the same day. ... States visit the emergency department (ED) because they are experiencing ...
... 2010) A team of researchers led by NewYork-Presbyterian ... predict post-stroke recovery of language by measuring the initial ... important implications for stroke survivors and their families, as ... are reported online in the journal Stroke . ...
... a world-leading publisher of scientific, technical and medical information ... a pilot project to evaluate the process by which ... VIVO instances. The pilot project, carried out by the ... a Scopus Custom Data dataset and will serve as ...
... College London, is to be the first ever recipient of ... contributions he has made to the field of movement disorders ... his delivery of the inaugural Lord Brain Memorial Lecture; "Brainwashed ... School on June 24, 2010. The Lord Brain Memorial ...
Cached Medicine News:Health News:Scientists Fashion New Lung for Rats 2Health News:Scientists Fashion New Lung for Rats 3Health News:Novel radiotracer shines new light on the brains of Alzheimer's disease patients 2Health News:Cardiac MRI in the ER cuts costs, hospital admissions for chest pain patients 2Health News:Cardiac MRI in the ER cuts costs, hospital admissions for chest pain patients 3Health News:New metric predicts language recovery following stroke 2Health News:VIVO utilizing Scopus custom data 2Health News:Lord Brain Memorial Lecture is launched in recognizing outstanding contribution to neuroscience 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: