Navigation Links
Lux Biosciences' Investigational Therapy for Uveitis, LX211, is,Subject of Two Presentations at Key Ophthalmology Meeting, ARVO,2007

JERSEY CITY, N.J.--(BUSINESS WIRE)--May 4, 2007 - Lux Biosciences, Inc., a privately held biotechnology company specialized in the field of ophthalmic diseases, announced today that the company's next-generation calcineurin inhibitor, LX211, is the subject of two presentations at the Association for Research in Vision and Ophthalmology (ARVO) annual meeting, being held May 6-10 in Fort Lauderdale, Florida.

The first, an oral presentation being given on May 5 during a satellite session of the American Uveitis Society by Quan Dong Nguyen, M.D. of the Wilmer Eye Institute, Johns Hopkins University and Hospitals, discusses the design of the ongoing LUMINATE (Lux Uveitis Multicenter Investigation of a New Approach to TrEatment) Phase 2/3 Clinical Trial Program. The three LUMINATE trials represent the first clinical development program aimed at supporting regulatory approval of a corticosteroid-sparing immunosuppressive agent in different types of sight-threatening, non-infectious uveitis.

The second, a poster presentation by Matthew A. Cunningham, senior medical student, senior author Robert Nussenblatt, MD, and collaborators from the National Eye Institute, Lux Biosciences, and Isotechnika, Inc., discusses preclinical data demonstrating the ability of subcutaneous injections of LX211 to prevent and reverse experimental autoimmune uveoretinitis (EAU) in rats. Cunningham commented, "We observed that in this animal model, LX211 could both prevent the onset of disease as well as reverse EAU at doses as low as 10 mg/kg. These preclinical results clearly support our view that LX211 may play an important future role in the treatment of uveitis."

The poster describes the induction of EAU in rats, which were then divided into three groups, designated preventative, therapeutic, and vehicle-control. Animals in the first two groups received daily subcutaneous injections of either cyclosporine A (CsA) at 40 mg/kg
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
2. An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes
3. Late Breaking Data Released at ADA Showed that the Investigational Use of Januvia and Metformin as Initial Combination Therapy Provided Significant Glucose Lowering Efficacy over 54 Weeks in Patients with Type 2 Diabetes
4. Investigational Study Demonstrated a Re-Establishment of Clinical Improvement with Orencia (Abatacept) in Children with Juvenile Idiopathic Arthritis upon Re-Introduction of Therapy
5. Mercks Investigational Migraine Treatment MK-0974 Significantly Improved Migraine Pain on Several Efficacy Measures in a Phase II Study
6. Data Demonstrated Metastatic Melanoma Response to Investigational Immunotherapy Ipilimumab
7. Investigational Drug Cediranib (AZD2171) Shows Promise in Patients With Recurrent Glioblastoma (GBM)
8. Additional New Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at ASCO Annual Meeting
9. Additional New Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at ASCO Annual Meeting
10. Investigational Cancer Drug Pertuzumab Shows Promising Results in Advanced Breast Cancer When Combined with Herceptin
11. Shire Announces Positive Results of Studies With Guanfacine Extended Release, An Investigational Nonstimulant Medication Filed for the Treatment of ADHD in Children and Adolescents
Post Your Comments:
(Date:1/15/2014)... As health officials across the Midwest warn against the ... Michigan will offer free diagnostic testing ... pharmacists to administer tests and, in some cases, fill the ... in the study. The Grand Rapids, ...
(Date:1/15/2014)... , Jan. 15, 2014 Massachusetts General Hospital ... AMGN ) announced today that they have ... validate new therapeutic targets and develop novel therapies ... that affects millions worldwide. The MGH-Broad-Amgen collaboration brings ...
(Date:1/15/2014)...  Manufacturers, suppliers and distributors of innovative medical-related products ... most important business assets, intellectual property (IP). ... Because of the highly-competitive nature of the Medical ... most litigious industry sectors of cases involving IP ...
Breaking Medicine Technology:Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4Intellectual Property Insurance for Medical-related Products and Services 2
... our ability to target experimental cancer treatments ... hand, and more are on the way ... drugs, MILAN, Italy, April 27 , At today,s ... Meeting,of the European Association for the Study of the Liver ...
... Virology Translate Into New Promising Drugs to Combat Hepatitis ... ... Stem Cells of Potential Benefit in Liver ... Liver Diseases, At today,s sessions of the 43rd Annual Meeting of the European,Association ...
Cached Medicine Technology:Molecular Discoveries Shed Light on Liver Cancer -- Hepatocellular Carcinoma (HCC) 2Molecular Discoveries Shed Light on Liver Cancer -- Hepatocellular Carcinoma (HCC) 3Basic Science Discoveries Yield Progress in Hepatology 2Basic Science Discoveries Yield Progress in Hepatology 3Basic Science Discoveries Yield Progress in Hepatology 4
(Date:7/11/2014)... (PRWEB) July 11, 2014 Wearing the school ... their families, facility and staff came together this past Saturday ... the Everest community in the Homer Township Independence Day Parade. ... to Old Glory. , Everest community recognized the ... float in red, white and blue. The blue Everest ...
(Date:7/11/2014)... Wa (PRWEB) July 11, 2014 Growing old was ... back then. However, in recent studies, it was shown that many ... no credence behind them. As it turns out, the elderly can ... , Of course, with all the time in the world, ... allows them to indulge their passions in the twilight of their ...
(Date:7/11/2014)... Newport Beach, CA (PRWEB) July 11, 2014 ... product pure Artichoke Leaf Extract dietary supplements to aid ... flow, an action necessary to facilitate metabolism of fat. ... facilities, Superior Labs Artichoke Leaf Extract is available in ... of pure artichoke extract. , Health Benefits of ...
(Date:7/11/2014)... TX (PRWEB) July 11, 2014 Plasma ... of blood products industry. Although the closure of 16 ... major disruption to domestic blood products market, the total ... 2.8% year on year and total lot release volume ... due to stock consumption, insufficient utilization of new plasma ...
(Date:7/11/2014)... People with physical disabilities and military ... the increasing numbers of people partnered with assistance dogs. ... productive lives. , But are these service dog ... dog an impediment to employment? , In honor ... - 9, 2014, West Virginia University associate professor and ...
Breaking Medicine News(10 mins):Health News:Everest Academy Participates in the Homer Township Independence Day Parade 2Health News:It’s All Free For Seniors Review, How To Take Advantage of What Life Has to Offer In Old Age – Vinamy.com 2Health News:It’s All Free For Seniors Review, How To Take Advantage of What Life Has to Offer In Old Age – Vinamy.com 3Health News:Artichoke Leaf Extract Released by SuperiorLabs Now Available on Amazon.com With 2 Day Prime Shipping 2Health News:Artichoke Leaf Extract Released by SuperiorLabs Now Available on Amazon.com With 2 Day Prime Shipping 3Health News:Chinese Blood Product Industry Report 2014-2017 Focuses Plasma Volume & Stations Says A New Research Available at ChinaMarketResearchReports.com 2Health News:Chinese Blood Product Industry Report 2014-2017 Focuses Plasma Volume & Stations Says A New Research Available at ChinaMarketResearchReports.com 3Health News:Chinese Blood Product Industry Report 2014-2017 Focuses Plasma Volume & Stations Says A New Research Available at ChinaMarketResearchReports.com 4Health News:Will Your Next Employee or Co-Worker Be a Dog? 2Health News:Will Your Next Employee or Co-Worker Be a Dog? 3Health News:Will Your Next Employee or Co-Worker Be a Dog? 4
... Pack Your Bag(TM) Events Bring Educational Outreach to Senior Centers ... , , PHILADELPHIA, June 29 Eight out of ... such as high blood pressure or diabetes. According to ... average of eight or more prescriptions regularly. With increased use ...
... from a single source , , BRIDGEWATER, ... provider of information and business intelligence for students, professionals ... the pharmaceutical industry, today introduced Wolters Kluwer Health ... an array of pharmaceutical forecasting capabilities. inThought was ...
... resource on hospital pharmacy operations, information technology and medication ... Dennis Tribble, PharmD, is now profiled at the ... http://expert411.com/_wsn/page3.html -- for media and professional ... VP Marketing for Baxa Corporation, who says Tribble is ...
... , ATLANTA, June 29 CryoLife, Inc., (NYSE: ... cardiovascular tissue processing company, today announced that, according to ... in more than 500,000 surgical procedures throughout the world ... and in the United States in 2001. BioGlue ...
... similar drugs failed, research finds , MONDAY, June 29 ... in treating rheumatoid arthritis patients who don,t respond to ... from the family of drugs called tumor necrosis factor-a ... in 10 countries who were randomly selected to receive ...
... , Combine to Integrate IBM Cognos BI Data with ... DALLAS, June 29 Vitria Technology, Inc., today announced ... that will enable IBM Cognos users to seamlessly integrate ... into customizable and flexible dashboards generated by Vitria,s Operational ...
Cached Medicine News:Health News:The National Council on Aging and CVS/pharmacy Educate Pennsylvania Seniors on Medication Management and How to Save Money on Prescription Drugs 2Health News:The National Council on Aging and CVS/pharmacy Educate Pennsylvania Seniors on Medication Management and How to Save Money on Prescription Drugs 3Health News:The National Council on Aging and CVS/pharmacy Educate Pennsylvania Seniors on Medication Management and How to Save Money on Prescription Drugs 4Health News:Wolters Kluwer Health's New Forecasting Service Models Pharma's Future 2Health News:Wolters Kluwer Health's New Forecasting Service Models Pharma's Future 3Health News:Baxa Corporation's Dennis Tribble, PharmD, Now Profiled at Expert411.com for Media and Professional Access 2Health News:Baxa Corporation's Dennis Tribble, PharmD, Now Profiled at Expert411.com for Media and Professional Access 3Health News:BioGlue(R) Surgical Adhesive Hits 500,000 Procedure Milestone Worldwide, Company Data Indicates 2Health News:BioGlue(R) Surgical Adhesive Hits 500,000 Procedure Milestone Worldwide, Company Data Indicates 3Health News:BioGlue(R) Surgical Adhesive Hits 500,000 Procedure Milestone Worldwide, Company Data Indicates 4Health News:New Drug Promising Against Rheumatoid Arthritis 2Health News:Motio and Vitria Deliver Unified Dashboard and OI Capabilities to IBM Cognos Users 2Health News:Motio and Vitria Deliver Unified Dashboard and OI Capabilities to IBM Cognos Users 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: