Navigation Links
Lux Biosciences' Investigational Therapy for Uveitis, LX211, is,Subject of Two Presentations at Key Ophthalmology Meeting, ARVO,2007

JERSEY CITY, N.J.--(BUSINESS WIRE)--May 4, 2007 - Lux Biosciences, Inc., a privately held biotechnology company specialized in the field of ophthalmic diseases, announced today that the company's next-generation calcineurin inhibitor, LX211, is the subject of two presentations at the Association for Research in Vision and Ophthalmology (ARVO) annual meeting, being held May 6-10 in Fort Lauderdale, Florida.

The first, an oral presentation being given on May 5 during a satellite session of the American Uveitis Society by Quan Dong Nguyen, M.D. of the Wilmer Eye Institute, Johns Hopkins University and Hospitals, discusses the design of the ongoing LUMINATE (Lux Uveitis Multicenter Investigation of a New Approach to TrEatment) Phase 2/3 Clinical Trial Program. The three LUMINATE trials represent the first clinical development program aimed at supporting regulatory approval of a corticosteroid-sparing immunosuppressive agent in different types of sight-threatening, non-infectious uveitis.

The second, a poster presentation by Matthew A. Cunningham, senior medical student, senior author Robert Nussenblatt, MD, and collaborators from the National Eye Institute, Lux Biosciences, and Isotechnika, Inc., discusses preclinical data demonstrating the ability of subcutaneous injections of LX211 to prevent and reverse experimental autoimmune uveoretinitis (EAU) in rats. Cunningham commented, "We observed that in this animal model, LX211 could both prevent the onset of disease as well as reverse EAU at doses as low as 10 mg/kg. These preclinical results clearly support our view that LX211 may play an important future role in the treatment of uveitis."

The poster describes the induction of EAU in rats, which were then divided into three groups, designated preventative, therapeutic, and vehicle-control. Animals in the first two groups received daily subcutaneous injections of either cyclosporine A (CsA) at 40 mg/kg
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
2. An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes
3. Late Breaking Data Released at ADA Showed that the Investigational Use of Januvia and Metformin as Initial Combination Therapy Provided Significant Glucose Lowering Efficacy over 54 Weeks in Patients with Type 2 Diabetes
4. Investigational Study Demonstrated a Re-Establishment of Clinical Improvement with Orencia (Abatacept) in Children with Juvenile Idiopathic Arthritis upon Re-Introduction of Therapy
5. Mercks Investigational Migraine Treatment MK-0974 Significantly Improved Migraine Pain on Several Efficacy Measures in a Phase II Study
6. Data Demonstrated Metastatic Melanoma Response to Investigational Immunotherapy Ipilimumab
7. Investigational Drug Cediranib (AZD2171) Shows Promise in Patients With Recurrent Glioblastoma (GBM)
8. Additional New Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at ASCO Annual Meeting
9. Additional New Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at ASCO Annual Meeting
10. Investigational Cancer Drug Pertuzumab Shows Promising Results in Advanced Breast Cancer When Combined with Herceptin
11. Shire Announces Positive Results of Studies With Guanfacine Extended Release, An Investigational Nonstimulant Medication Filed for the Treatment of ADHD in Children and Adolescents
Post Your Comments:
(Date:9/18/2014)... YORK , Sept. 18, 2014 This BCC Research ... share of major players, market growth and size, and opportunities ... trends and revenue through 2018. Patent analysis in the report ... as the U.S., Europe and ... to: - Define and discuss the global medical device technologies ...
(Date:9/18/2014)... Sept. 18, 2014   Fruit Street Health ... initial seed round of funding. The ... by a series of individual investors, the majority of ... in the initial round are; Houston Cardiology Consultants ... Urologist Stacy Childs, Rapha Family Medicine Practice Owner ...
(Date:9/18/2014)... 2014  ADM Tronics Unlimited, Inc. (OTCQB: ADMT) ... its corporate Advisory Board for business development. ... Harvard Medical School and Visiting Professor at the ... Masters degree in Electronics Engineering and his Ph.D. ... Bologna. After spending a year as a visiting ...
Breaking Medicine Technology:Medical Devices: Technologies and Global Markets 2Medical Devices: Technologies and Global Markets 3Medical Devices: Technologies and Global Markets 4Fruit Street Health Secures First Round Of Seed Funding Led By Group Of Medical Industry And Technology Leaders 2Fruit Street Health Secures First Round Of Seed Funding Led By Group Of Medical Industry And Technology Leaders 3ADM Tronics Appoints Gianluca DeNovi, Ph.D. To Advisory Board 2ADM Tronics Appoints Gianluca DeNovi, Ph.D. To Advisory Board 3
... ADDISON, Texas, March 11, 2011 U LURUInc.(NYSE ... the development of a portfolio of wound management and oral ... NYSE Amex LLC (the "Exchange") advising ULURU that it is ... continued listing standards under Section 1003 of the Exchange,s Company ...
... (Nasdaq: NVAX ), a clinical-stage vaccine company, announced ... be presenting at the ROTH 23rd Annual OC Growth Stock ... at The Ritz Carlton, Laguna Niguel, CA.  A live audio-only ... Company website at www.novavax.com under Investors/Events, and a ...
Cached Medicine Technology:ULURU Inc. Receives Letter of Non-Compliance From NYSE Amex 2
(Date:9/19/2014)... California (PRWEB) September 19, 2014 Final Cut ... the production of the Float Theme template for Apple's ... and a simplistic template that allows FCPX users to create ... X," said Christina Austin, CEO of Pixel Film Studios, "With ... of the environment with the Float Theme." , Float ...
(Date:9/19/2014)... 2014 There are thousands of older women ... intimacy, and there are thousands of younger men who would ... SeekingCougar.com now provides the world's best collection of ... to older women, and the younger men who would like ... for these people to meet each other and establish those ...
(Date:9/18/2014)... 19, 2014 Reduce bags under the ... just for these issues in a serum. , "Our ... Eyeliss," says Kathy Heshelow, founder of Sublime Beauty®. "Each ... boosting collagen, to improve the eye area." , Today ... for wrinkles, dark circles and bags at Amazon with ...
(Date:9/18/2014)... Kent, WA (PRWEB) September 18, 2014 ... at Lake Meridian Chiropractic are pleased to announce that Dawn ... the 24-year-old clinic. Dr. Saggau looks forward to Ms. ... operational and administrative talents will make her a key contributor. ... unique combination of educational, professional, and personal experiences that ...
(Date:9/18/2014)... 18, 2014 Alexandria, VA — The ... that 10 more communities have joined the growing ranks ... department accreditation. The decisions bring the number of governmental ... PHAB is the non-profit organization that administers the national ... protect the health of the public by advancing the ...
Breaking Medicine News(10 mins):Health News:Pixel Film Studios Releases Float Theme for Final Cut Pro X Users 2Health News:Dating Site "SeekingCougar.com" Now Offering Tips for Younger Men Seeking Older Women 2Health News:The Secret to Improving Under-Eye Skin: 30% Off Sale and Report on Ingredients Ends Tonight on the Face Whisperer® Advanced Eye Gel 2Health News:Lake Meridian Chiropractic of Kent, WA Announces that Dawn Kelly Has Been Promoted to the Position of Office Manager 2Health News:Ten More Communities Reaping Benefits of National Accreditation 2Health News:Ten More Communities Reaping Benefits of National Accreditation 3Health News:Ten More Communities Reaping Benefits of National Accreditation 4
... finds , THURSDAY, June 11 (HealthDay News) -- Mad cow ... somehow goes astray and deprives the healthy brain cells of ... considered a prion disease because it has been found to ... is found on the surface of many cells -- including ...
... ... media age. , ... (Vocus) June 11, 2009 -- From cyberbullying and violent video games to social networking and ... To help parents navigate this new and changing landscape, the Center on Media and ...
... of the crime in cancer are guilty of the initiation and ... disease, a team led by scientists at The University of Texas ... Cancer Cell . "We have a smoking gun" that ... that makes them are abnormally expressed in many types of cancer, ...
... Wii may help treat symptoms of Parkinson,s disease, including ... Parkinson,s disease is a degenerative disease that impairs ... game console, which simulates various sports and activities, could ... found additional benefits as well. "The Wii allows ...
... fifth most common malignancy worldwide and the third leading ... been associated with HCC. However, the relationship between type ... the effects of antidiabetic therapy on HCC risk have ... led by Dr. Valter Donadon from Pordenone Hospital addressed ...
... common cancers in China. Although the association between the ... the relation between smoking, alcohol drinking, family history of ... still remains uncertain. So it is important to investigate ... sporadic colorectal cancer. A research team led by ...
Cached Medicine News:Health News:Protein Branded As Culprit in Mad Cow Disease 2Health News:Center on Media and Child Health Launches "Ask the Mediatrician" 2Health News:Center on Media and Child Health Launches "Ask the Mediatrician" 3Health News:Researchers identify 4 new targets for breast cancer 2Health News:Wii-hab may enhance Parkinson's treatment 2
... test device provides clear, reliable ... results can be determined in ... positive results require only 8 ... sample application will dependably and ...
AccuSign® DOA Series Opiates Test...
Accu-Stat Home Drug Test for Marijuana (THC), Cocaine (COC), Amphetamine (AMP), Methamphetamine (mAMP), Opiates (OPI), and Phencyclidine (PCP)....
... ESR products, SEDIPLAST® is a completely ... to protect laboratory personnel from the ... is a uniquely designed erythrocyte sedimentation ... safety and convenience as well as ...
Medicine Products: