Navigation Links
Lumiracoxib Study Showed Significantly Less Impact on Blood,Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled,Hypertension

New data From 741-patient Trial Show Those Treated with Lumiracoxib Experienced Significantly Smaller Impact on Blood Pressure Compared to Ibuprofen

EAST HANOVER, N.J., June 15, 2007 /PRNewswire/ -- Patients with osteoarthritis who also have controlled hypertension experienced a slight decrease in average daily blood pressure when treated with the investigational selective COX-2 inhibitor lumiracoxib compared to a slight increase in those taking ibuprofen, a commonly-used non-steroidal anti-inflammatory drug (NSAID).

These new results, presented today at the Annual European Congress of Rheumatology (EULAR) in Barcelona, are important because around 40% of patients with osteoarthritis also have high blood pressure (or hypertension).

While this study did not assess long-term cardiovascular outcomes, independent research shows that even small elevations in blood pressure can contribute to an increased risk of cardiovascular events. Osteoarthritis is the most common form of arthritis affecting 21 million Americans.

"NSAIDs, including some COX-2s, have been associated with raised blood pressure, and this effect may be in part responsible for the increased risk of cardiovascular disease associated with this class of medications," said Tom MacDonald, Ph.D., Professor of Clinical Pharmacology at the Hypertension Research Centre at Ninewells Hospital & Medical School in Dundee, Scotland. "These data indicate that lumiracoxib may have less impact on blood pressure than the most commonly used NSAID ibuprofen."

In the US, lumiracoxib 100 mg once-daily is under review by the Food and Drug Administration (FDA) for relief of the signs and symptoms of osteoarthritis.

"Evidence from the large-scale TARGET study has shown that lumiracoxib is associated with significantly smaller increases in blood pressure than commonly used NSAIDs," said James Shannon, MD, Global Head of Development at Nov
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
2. Clinical Study Shows Regenecare Relieves Pain and Itching of Skin Rashes Caused by Widely Used Cancer Drugs
3. Cell Therapeutics, Inc. Management to Discuss Todays Announcement of Interim Pixantrone Study Results
4. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
5. Reaction to Avandia Warnings Stronger Among Internists Than Endocrinologists, According to Study by GfK Market Measures
6. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
7. Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis
8. Protox Announces Positive Clinical Data from Prostate Cancer Study
9. International ENDORSE Study Shows That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE prophylaxis
10. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
11. Genzyme Announces Data from First Phase 3 Study of Tolevamer in Patients with C. difficile Associated Diarrhea
Post Your Comments:
(Date:10/20/2014)... VIEW, California , 20 de octubre de ... líder en el campo de la pulmonología intervencional, ... su Estudio RENEW, casi 3 meses antes de ... fundamental de exención de dispositivo de investigación (IDE) ... Medicamentos) para el sistema de espiral de reducción ...
(Date:10/20/2014)... SAN DIEGO , Oct. 20, 2014   BioNano ... the Irys system: the ability to collect human data at ... on a single chip.  This new capability was established and ... for the Irys TM System and will ... next two months. BioNano will be showcasing this advancement at ...
(Date:10/20/2014)...   Mary,s Medicinals today announced that its ... Sponsor of Operation Grow4Vets , a national, nonpartisan ... and services to assist them in living with injuries ... , An ever-increasing number of medical studies ... treatment for pain, Post-traumatic Stress Disorder (PTSD) and Traumatic ...
Breaking Medicine Technology:PneumRx concluye inscripción en prueba fundamental RENEW 2PneumRx concluye inscripción en prueba fundamental RENEW 3BioNano Genomics Announces One Human : One Chip : One Day 2BioNano Genomics Announces One Human : One Chip : One Day 3Mary's Medicinals Announces 4-Star Sponsorship of Operation Grow4Vets 2Mary's Medicinals Announces 4-Star Sponsorship of Operation Grow4Vets 3
... 2011 Reportlinker.com announces that a new market research report ... In Vitro Diagnostics Market http://www.reportlinker.com/p0470752/World-In-Vitro-Diagnostics-Market.html ... through 2014 The Freedonia Group projects world ... annually to nearly $68 billion in 2014. Based on the ...
... Reportlinker.com announces that a new market research report ... European Markets for Patient Monitoring Devices and Equipment ... In 2010, the European patient monitoring ... 2008 and 2009. This mature market is expected ...
Cached Medicine Technology:Reportlinker Adds World In Vitro Diagnostics Market 2Reportlinker Adds World In Vitro Diagnostics Market 3Reportlinker Adds World In Vitro Diagnostics Market 4Reportlinker Adds World In Vitro Diagnostics Market 5Reportlinker Adds World In Vitro Diagnostics Market 6Reportlinker Adds World In Vitro Diagnostics Market 7Reportlinker Adds World In Vitro Diagnostics Market 8Reportlinker Adds World In Vitro Diagnostics Market 9Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 2Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 3Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 4Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 5Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 6Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 7Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 8Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 9Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 10Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 11Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 12Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 13Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 14Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 15Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 16Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 17Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 18Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 19Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 20Reportlinker Adds European Markets for Patient Monitoring Devices and Equipment 2011(15 Countries) 21
(Date:10/20/2014)... T.E.N., a technology and information ... that William H. Murray, renowned author and industry ... Leadership Award winner. Presented annually, the ISE® Luminary ... leader and industry practitioner for his or her ... information security industry. , Formerly with IBM, Murray ...
(Date:10/20/2014)... My Clients Plus ( http://www.MyClientsPlus.com ) today ... new module enables easy administration and routing of follow-up ... , This application allows users such as Therapists to ... to-do item to a specific client, categorize tasks the ... reminders for follow-ups. It's designed to enable easy ...
(Date:10/20/2014)... 20, 2014 Rockynol Retirement Community ... on Oct. 14. The $11 million project will include ... a cooked-to-order kitchen with full-service restaurant style dining. , ... for first class Assisted Living apartments,” said Kara Hanzie, ... the highest quality of care and this investment is ...
(Date:10/20/2014)... California (PRWEB) October 20, 2014 Final Cut ... the release of the Citrus theme for FCPX filmmakers ... would use to describe the Citrus theme” Says Christina Austin, ... easy to look so professional.” , Citrus comes with all ... with the template are: four transitions for added style, a ...
(Date:10/20/2014)... Houston, Texas (PRWEB) October 20, 2014 ... invited to present the key elements of his innovative ... visiting professor to plastic surgery residents and faculty at ... (UTMB) , where he, too, was once a medical ... of the largest private cosmetic plastic surgery practices in ...
Breaking Medicine News(10 mins):Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 2Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 3Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 4Health News:My Clients Plus Announces New Workflow Management Software 2Health News:Rockynol Retirement Community Expands Assisted Living Center 2Health News:Today Pixel Film Studios Announced the Release of the Citrus theme for Final Cut Pro X 2Health News:Plastic Surgeon Patronella Presents Artistically-Inspired Tummy Tuck Method to Future Generation of Plastic Surgeons in Texas 2
... has been forbidden in Sweden since 1999. The Sex Purchase ... a practice that is not acceptable in Sweden. Two years ... the aim of integrating sex sellers into society. Since then ... benefit and pensions in the same way as all other ...
... Blind Persons Return to Work Act of 2009 ... John Lewis (D-GA) has introduced legislation designed to ... (SSDI) to return to work. The Blind ... 886), will eliminate penalties that prevent blind persons ...
... less cell degeneration , , SUNDAY, Feb. 8 (HealthDay ... to slow or stop Alzheimer,s disease in recent studies ... entorhinal cortex, which supports memory, normally produces brain-derived neurotrophic ... Alzheimer,s is present. When researchers injected BDNF in lab ...
... Don,t let your body pay the price in uncertain ... News) -- The economic news is enough to weaken ... stressed, eating poorly and cutting out workouts while trying ... in patients complaining about heart palpitations, anxiety and stress ...
... Genesis,Pharmaceuticals Enterprises, Inc. (OTC Bulletin Board: GNPH) ... with its principal operations in the,People,s Republic ... Arbitration,Association ("AAA") arbitration panel rejected requests by ... $13.8 million and Capital Research Group,Partners, Inc. ...
... Estrogen appears to improve kidneys, ability to shed sodium, ... Hormones and a cell receptor in the kidneys may ... with salt-sensitive hypertension, a new study says. , Salt-sensitive ... than necessary. This drives up blood pressure as the ...
Cached Medicine News:Health News:Is sex work? 2Health News:National Federation of the Blind Praises Bill to Create Work Incentives and Opportunity 2Health News:Brain Protein May Have Potential Against Alzheimer's 2Health News:Healthy Heart Tips for a Bad Economy 2Health News:Genesis Pharmaceuticals Successfully Defends Itself in a Multi-Million Dollar Arbitration, Two Other Arbitration Proceedings Against Genesis are Withdrawn 2Health News:Genesis Pharmaceuticals Successfully Defends Itself in a Multi-Million Dollar Arbitration, Two Other Arbitration Proceedings Against Genesis are Withdrawn 3Health News:Female Hormones Deter Salt-Sensitive Hypertension 2
... Cadwell's custom bars have a ... solid, machined contacts (spaced 3 centimeters ... tear of repeated cleaning. Polarity indicators ... convenient, snap-on handle fits our bar ...
... custom bars have a large body ... contacts (spaced 3 centimeters center-to-center) to ... repeated cleaning. Polarity indicators are molded ... handle fits our bar electrode styles. ...
... first lens of its kind to receive FDA ... elimination of myopia in adults with myopia ranging ... aged 21 and over. With over 18 ... results prove that the Verisyse design is safe ...
... The Plume-inator produces the ... family of smoke evacuators. ... test button, hospital grade plug, ... and dual purpose swing ring ...
Medicine Products: