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Long-Term Pegylated Interferon Alfa-2b Therapy in Stage III,Melanoma Demonstrated Significant and Sustained Impact on,Relapse-Free Survival

een previously treated with interferon alpha and who are at least 18 years of age.


Interferon is a protein produced naturally by white blood cells that stimulates the growth of certain disease-fighting blood cells in the immune system. Pegylated interferon is a longer-acting form of interferon. It is made by attaching an inert molecule called polyethylene glycol, or PEG, to the alpha interferon molecule. This process increases the size of the interferon so it is eliminated from the body more slowly. Pegylation allows for once-weekly dosing rather than the three-times-weekly dosing required for standard interferon.
Schering-Plough Corporation is a global science-based health care company with leading prescription, consumer and animal health products. Through internal research and collaborations with partners, Schering-Plough discovers, develops, manufactures and markets advanced drug therapies to meet important medical needs. Schering-Plough's vision is to earn the trust of the physicians, patients and customers served by its more than 33,500 people around the world. The company's Web site is www.scheringplough.com.
Created in 1962, the European Organisation for Research and Treatment of Cancer (EORTC) is a not-for-profit international cancer research organisation under the Belgian Law. The EORTC has the mission to develop, conduct, coordinate and stimulate laboratory and clinical research in Europe to improve the management of cancer and related problems by increasing survival but also patients’ quality of life. The ultimate goal of the EORTC is to improve the standard of cancer treatment in Europe, through the development of new drugs and other innovative approaches, and to test more effective therapeutic strategies, using drugs which are already commercially available, or surgery or radiotherapy.

The EORTC has the aim to facilitate the passage of expe
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