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Liponex Inc. Reports Further Analysis of CRD5 Phase I/II Clinical,Trial Data

which inhibit the secretion of gastric acid and reduce the acidity of the stomach. Patients that took PPI regularly during the trial showed an increased CRD5 efficacy with a mean HDL increase from baseline of 16% at 1 gram (n=4) and 14% at 3 grams (n=3).

"We are very encouraged by these results. We are seeing the best effect in patients that can most benefit from CRD5, at dose levels that are commercially viable," said Bill Dickie, President and CEO of Liponex. "These results, particularly the impact of PPI on CRD5 efficacy, support our ongoing preclinical studies and guide our strategy to optimize the formulation and dosing regimen for CRD5 clinical development."

The company believes that it can resolve CRD5 pH sensitivity and boost the efficacy of CRD5 with well-established enteric coating strategies. Preclinical experimental work is underway to confirm this view and then an additional clinical trial will be undertaken with results expected in the first quarter of 2008. The company has filed a novel formulation patent application to cover these initial findings and to further protect its competitive position.

About Liponex Liponex is a biopharmaceutical company specializing in developing products related to High Density Lipoprotein (HDL), often called "good cholesterol." Its drug candidates relate to the various roles of HDL as a transport vehicle, including removing excess cholesterol from the body, delivering molecules to cells and removing unwanted materials from the body. Liponex is listed on the TSX under the ticker "LPX". For more information on Liponex, visit www.liponex.ca.

Certain of the statements contained in this press release contain forward-looking statements which involve known and unknown risks, uncertainties and other important factors which may cause the actual results, performance or achievements of the Company, or industry results, to be materially different from
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TAG: Liponex Inc Reports Further Analysis CRD5 Phase Clinical Trial Data
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