NEW ORLEANS--(BUSINESS WIRE)--Mar 27, 2007 - Pfizer announced today
that Lipitor(R) (atorvastatin calcium) Tablets (80 mg) lowered
hospitalization costs by significantly reducing the risk of
cardiovascular events in patients with heart disease, according to
two separate economic analyses. The data were presented at the
annual meeting of the American College of Cardiology.
"One of these analyses suggests that even with the availability
of low cost generics, intensive Lipitor therapy is a good economic
value," said Dr. Peter Lindgren, managing director of European
Health Economics in Stockholm, Sweden, and lead investigator of the
economic evaluation of the Incremental Decrease in Endpoints
through Aggressive Lipid Lowering (IDEAL) trial. "The economic
impact of heart attacks and strokes in the U.S. alone totals more
than $400 billion in medical care and lost productivity
annually."
New IDEAL Health Economic Analysis
In a new post-hoc analysis of a subset of patients (n=999) in
the IDEAL study that had acute coronary syndrome (i.e. had a heart
attack less than two months prior to entering the study):
-- Hospitalization costs during the five-year trial were 21
percent lower for Lipitor 80 mg ($6,427 per patient) than for
simvastatin 20 mg--40 mg ($8,179 per patient).
-- This finding was due to the significant 21 percent reduction
in the risk of any cardiovascular event for these patients.
Even in a low cost generic market, treatment of acute coronary
syndrome patients with Lipitor 80 mg is predicted to reduce
cardiovascular events at an acceptable incremental cost over
simvastatin 20 mg-40 mg.
On average in the U.S., coronary heart disease, including heart
attacks, costs $ 96,467 in direct costs per patient, a stroke costs
$59,429 and certain types of heart surgery cost $122,122.
"As physicians, payers and employers come under increasing
pressure to reduce medical h
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