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Lipitor Provides Unprecedented Cardiovascular Risk Reductions in,Diabetes Patients with Metabolic Syndrome and in Stroke Patients

etabolic Syndrome

Metabolic syndrome was defined in this analysis using the International Diabetes Federation criteria of central obesity and two or more of the following conditions: diabetes, treated hypertension or high blood pressure, high triglyceride and low levels of good cholesterol (HDL).

Nearly 47 million Americans currently live with metabolic syndrome according to the American Heart Association. According to the International Diabetes Foundation, a quarter of the world's adults have metabolic syndrome and people with metabolic syndrome are twice as likely to die from, and three times as likely to have, a heart attack or stroke compared with people without the syndrome.

New Analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) study

A new SPARCL analysis was conducted to evaluate if treatment with Lipitor 80 mg was associated with significant protection from coronary events after a recurrent stroke or mini-stroke. In more than 850 patients who suffered a recurrent stroke or mini-stroke during the trial:

-- Lipitor 80 mg reduced patients' risk of experiencing major coronary events (death from cardiac causes, heart attack, or resuscitation after cardiac arrest) by 53 percent compared with placebo.

The benefits of Lipitor 80 mg in patients with a recurrent stroke or mini-stroke seen in this analysis are consistent with the primary SPARCL results which demonstrated the benefit of Lipitor 80 mg in reducing stroke and coronary events among all patients in the study (n=4,731).

About Stroke

Stroke is the third leading cause of death and the leading cause of adult disability in the United States and industrialized European nations. About 700,000 Americans and 1.1 million Europeans suffer from a stroke or mini-stroke annually.

According to a recent article in the journal Neurology, many patients hospitalized with stroke or mini-stroke, including those with known high ch
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