Navigation Links
LifeCycle Pharma Announces Positive Phase I Clinical Results for,its Transplantation Product Candidate, LCP-Tacro

Heads into US Phase II Clinical Trials for Organ Transplantation

HORSHOLM, Denmark, May 31, 2007 /PRNewswire-FirstCall/ -- LifeCycle Pharma announces positive Phase I clinical results for its transplantation product candidate, LCP-Tacro - Heads into US Phase II clinical trials for organ transplantation.

Today LifeCycle Pharma A/S (OMX:LCP) announces positive results from its Phase I clinical trial program of LCP-Tacro, a proprietary, once-daily tacrolimus tablet.

A series of Phase I trials, involving more than 150 healthy volunteers demonstrate that LCP-Tacro:

- Has a once-daily profile.

- Delivers consistently higher bioavailability of about 50% compared to Prograf(R).

- Reduces peak levels (Cmax) and reduces peak (Cmax) / trough (Cmin) fluctuation compared to Prograf(R).

"The once-daily profile and significant increase in bioavailability, compared to Prograf(R), that has been demonstrated for our LCP-Tacro product candidate in an extensive Phase I program is encouraging, and provides the foundation to quickly advance it into Phase II trials for organ transplantation, said Dr. Flemming Ornskov, President and CEO of LifeCycle Pharma". LifeCycle Pharma's long-term strategy is to concentrate on and commit significant resources to the development of a number of product candidates for organ transplantation as it moves towards becoming a fully integrated specialty pharmaceutical company" added Dr. Ornskov.

About the studies:

LifeCycle Pharma has conducted a series of Phase I studies in more than 150 healthy volunteers to demonstrate the profile of LCP-Tacro under single-dose and multi-dose (steady-state) conditions. In addition to this, dose-linearity, food-effect and diurnal pharmacokinetic studies have been completed.

About transplantation:

In order to prevent the patient's immune system from rejecting the transplanted organ, immunosuppression t
'"/>




Page: 1 2 3

Related medicine technology :

1. Sygnis Pharma AG announces date for presentation of clinical results
2. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
3. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
5. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
6. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
7. Sunesis Pharmaceuticals to Present at the C. E. Unterberg, Towbin Emerging Growth Conference
8. EPIX Pharmaceuticals to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
9. Array BioPharma to Present at the C.E Unterbeg, Towbin Emerging Growth Conference
10. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
11. TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment
Post Your Comments:
(Date:3/27/2015)... 27, 2015 A new report from Kalorama Information ... – Chile , Colombia ... targets for IVD firms.  The healthcare research firm said that ... strategies for the Latin American continent with a population of ... supply operations. However, the country,s regional economic clout does not ...
(Date:3/27/2015)... LONDON , March 27, 2015 ... commercial prospects for leading ophthalmic drug companies  ... the pharma ophthalmic industry ? Visiongain,s brand new ... trends, opportunities and prospects there. Our 242-page ... most lucrative areas in the industry and the future ...
(Date:3/27/2015)... , March 27, 2015   Hospira, Inc. ... in biosimilars and the world,s leading provider of ... that support an evaluation of biosimilarity of its ... and Drug Administration (FDA) conditionally approved name of ... (epoetin alfa). These study data were presented at ...
Breaking Medicine Technology:Kalorama: Beyond Brazil, Latin American IVD Market Grows 2Kalorama: Beyond Brazil, Latin American IVD Market Grows 3Kalorama: Beyond Brazil, Latin American IVD Market Grows 4Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 2Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 3Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 4Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 5Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 6Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 7Hospira Clinical Data Shows Proposed Biosimilar, Epoetin Hospira, Demonstrates Pharmacokinetic And Pharmacodynamic Equivalence Compared To Amgen's Epogen 2Hospira Clinical Data Shows Proposed Biosimilar, Epoetin Hospira, Demonstrates Pharmacokinetic And Pharmacodynamic Equivalence Compared To Amgen's Epogen 3
... /PRNewswire-Asia/ -- From the 1st to the 3rd of ... will meet at Vaccine World Summit in New Delhi. ... with DCVMN (Developing Countries Vaccine Manufacturers Network). ... health challenges including appropriate pandemic surveillance programs, low cost ...
... ANGELES, Dec. 7, 2010 Despite unemployment levels being at ... the IT world are experiencing a shortage of trained and ... for these job sectors are proving to be an instrumental ... the job market. As a popular vocational school in ...
Cached Medicine Technology:World Vaccine Leaders to Meet in New Delhi India to Tackle Global Public Health Challenges 2Coast Career Institute's Expedited Training Program for Diagnostic Medical Sonography Helps Students Land the Highly Specialized Jobs They Seek 2
(Date:3/28/2015)... Las Vegas, NV (PRWEB) March 28, 2015 ... stiffness may not be necessary, according to research presented ... ( AOSSM ) Specialty Day. , “Our study compared ... with 25 who underwent an additional glenohumeral joint capsule ... surgery,” commented George Murrell MD, PhD, lead author from ...
(Date:3/28/2015)... Portland, OR (PRWEB) March 28, 2015 ... in the media regarding recent changes and proposals around ... TV , current and former collegiate student-athletes across a ... experiences and reflect on common challenges. The special panel ... the country in sports ranging from football, track and ...
(Date:3/28/2015)... 2015 Designers and Professionals of ... Scratches 5K from Pixel Film Studios. , “Scratches 5K ... media inside Final Cut Pro X” Said Christina Austin, ... and is an effective tool for any FCPX editor.” ... 5K's intuitive grunge overlays. Simply drag title layers into ...
(Date:3/28/2015)... 2015 LTW Cyber is an innovation ... for the purpose of addressing the needs of the ... its own opportunities to grow while seeking collaborative opportunities ... Cyber. , Ventures in LTW Cyber focus on secure ... offerings identifying vulnerabilities and analyzing open source. As ...
(Date:3/27/2015)... 27, 2015 Florida Hospital is excited to ... team’s exclusive health care provider for the 2015 and 2016 ... provides medical care and an athletic trainer for the team ... off its season against the Cleveland Gladiators at Amalie Arena; ... is extremely important to us as it gives us the ...
Breaking Medicine News(10 mins):Health News:No Need to Delay Rotator Cuff Surgery, Study Shows 2Health News:SCI TV Panel of Former College Athletes Discusses Student Athlete Experience 2Health News:SCI TV Panel of Former College Athletes Discusses Student Athlete Experience 3Health News:Pixel Film Studios Unveiled Scratches 5k for Final Cut Pro X Editors 2Health News:Canadian Cybersecurity Ventures Globalize as a Collective 2Health News:Canadian Cybersecurity Ventures Globalize as a Collective 3Health News:Florida Hospital Is Kicking off the 2015 Season as the Exclusive Health Care Provider for the Tampa Bay Storm 2Health News:Florida Hospital Is Kicking off the 2015 Season as the Exclusive Health Care Provider for the Tampa Bay Storm 3
... less likely than non-Hispanic whites to call 9-1-1 and be ... in medical treatment delays according to a new study ... ., For the study, researchers used data from the Brain ... hospital arrival time and use of ambulance or emergency medical ...
... with a coalition of 20 international sites in five ... who have had optical coherence tomography (OCT) of the ... researchers hope will give doctors a better means to ... and sudden cardiac death. When a vulnerable ...
... say , THURSDAY, March 25 (HealthDay News) -- New research ... cancer may actually improve their survival odds, a notion contrary ... finding is significant, given that the death rate from breast ... pregnancy until later in life, the study authors said. , ...
... compared to about three-quarters of whites, Hispanics, CDC says ... the health-boosting powers of breast-feeding aren,t reaching black American ... a new study from the U.S. Centers for Disease ... that while more than 80 percent of Hispanic mothers ...
... how tumors escape the body,s natural immune surveillance has recently ... Switzerland. The study shows how tumors can create a tolerant ... key features of lymph nodes. The discovery, published in ... 25, 2010, underscores the role of the lymphatic system in ...
... ... to Raise Awareness About Malaria Prevention Aboard an Eco-Friendly Bus , ... Atlanta, GA (Vocus) March 25, 2010 -- The United ... in Africa — announced today the launch of its Nothing But Nets Buzz Tour. The ...
Cached Medicine News:Health News:Mexican Americans less likely than whites to call 9-1-1 for stroke 2Health News:Mexican Americans less likely than whites to call 9-1-1 for stroke 3Health News:Mass. General Hospital to create registry for coronary optical coherence tomography 2Health News:Pregnancy May Protect Breast Cancer Survivors 2Health News:Pregnancy May Protect Breast Cancer Survivors 3Health News:Black Women Least Likely to Breast-Feed in U.S. 2Health News:Black Women Least Likely to Breast-Feed in U.S. 3Health News:Tumors hide out from the immune system by mimicking lymph nodes 2Health News:Grassroots Campaign Drives toward Ending Malaria Deaths by 2015 2Health News:Grassroots Campaign Drives toward Ending Malaria Deaths by 2015 3
... If you prefer a standard ... the Volk Iridectomy Lens. Its ... view you're used to but ... Volk's exclusive Double Aspheric design ...
... The re-designed Super Macula® 2.2 offers extremely ... the fovea, while achieving an exceptionally wide ... an excellent choice for critical evaluation of ... stereopsis for detailed views of the macula ...
... is designed for focal laser therapy and ... design presents a realistic contour of the ... of the entire posterior pole extending to ... lens allows dynamic movement on the globe, ...
... The Digital 1.0x Imaging Lens is optimized ... reduce glare and reflections during general diagnosis and ... view of the posterior pole and a sharper ... Digital 1.0 X Imaging Lens is also ideal ...
Medicine Products: