Late Breaking Data Released at ADA Showed that the Investigational,Use of Januvia and Metformin as Initial Combination Therapy,Provided Significant Glucose Lowering Efficacy over 54 Weeks in,Patients with Type 2 Diabetes
treated with pioglitazone rescue. In combination with metformin JANUVIA provided significantimprovements in A1C FPG and 2-hour PPG compared to placebo withmetformin (Table 3). Rescue glycemic therapy was used in 5% ofpatients treated with JANUVIA 100 mg and 14% of patients treated withplacebo. A similar decrease in body weight was observed for bothtreatment groups.